Zobrazeno 1 - 10
of 20
pro vyhledávání: '"David C. McFarland"'
Autor:
Heath C. Thomas, Marshall S. Scicchitano, Kendall S. Frazier, David C. McFarland, Dana C. Pietrzak, Roberta A. Thomas
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 60:263-274
Introduction There are currently few widely accepted noninvasive detection methods for drug-induced vascular damage. Circulating endothelial progenitor cell (EPC) enumeration in humans has recently gained attention as a potential biomarker of vascula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb0873604f50fbe8da8703f3becf981e
https://doi.org/10.1016/j.vascn.2009.06.002
https://doi.org/10.1016/j.vascn.2009.06.002
Publikováno v:
Cytometry Part A. :86-94
Background: Flow cytometric analysis and cell-sorting of peripheral blood leukocytes is commonplace; however, platelet contamination is typically ignored during immunophenotypic analysis and sorting of blood-derived cells. Methods: Red blood cells, p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d72a22a3a9b76d83790aded1743c3f9
https://doi.org/10.1002/cyto.a.20207
https://doi.org/10.1002/cyto.a.20207
Autor:
Padma K. Narayanan, Marshall S. Scicchitano, David C. McFarland, Lester W. Schwartz, Lauren A. Tierney
Publikováno v:
Experimental Hematology. 31:760-769
Objective. Erythropoiesis involves proliferation and differentiation of committed erythroid progenitors to mature red blood cells. The objective of this study was to characterize growth characteristics of human CD36 + erythroid progenitors and to pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::736bc33d32673cfde86b134893d6cda1
https://doi.org/10.1016/s0301-472x(03)00185-1
https://doi.org/10.1016/s0301-472x(03)00185-1
Autor:
David C. McFarland, D. Gwyn Morgan, Cindy Zhang, Timothy K. Hart, Padma K. Narayanan, Laura M Hahn, Lester W. Schwartz, Peter J. Bugelski, Fiona Elcock
Publikováno v:
Cytometry. :28-35
Background Troglitazone (TRO), a thiazolidinedione (TZD) peroxisome proliferator-activated receptor γ agonist, was recently withdrawn from the market because of rare but serious hepatotoxicity. Previous studies investigating the cytotoxicity of TRO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dfeb77fa2c65f88c7d126019d4ed059
https://doi.org/10.1002/cyto.a.10011
https://doi.org/10.1002/cyto.a.10011
Autor:
David C. McFarland
Publikováno v:
Emu - Austral Ornithology. 102:315-321
The short-term energetic and long-term reproductive costs and benefits of aggressive social behaviour of New Holland Honeyeaters were examined in an open forest where nectar availability for part of the year was highly unpredictable. Despite the vari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f2376fd15310b8815ba8f7b9c1fbbf1
https://doi.org/10.1071/mu01057
https://doi.org/10.1071/mu01057
Autor:
Hong Ni, Laura M Hahn, Padma K. Narayanan, Kevin T. Morgan, Catherine X. Hu, Mark Tirmenstein, Gina R. Benavides, David C. McFarland, Lawrence W. Yoon, Marilyn Easton, Christine L. Merrill, Heath C. Thomas, Donald R Creech
Publikováno v:
Toxicological Sciences. 68:93-101
Although they are known to be effective antidiabetic agents, little is published about the toxic effects of carnitine palmitoyltransferase-1 (CPT-1) inhibitors, such as etomoxir (ET). These compounds inhibit mitochondrial fatty acid beta-oxidation by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b18f31763eecab43b1b41b5484f91e7
https://doi.org/10.1093/toxsci/68.1.93
https://doi.org/10.1093/toxsci/68.1.93
Autor:
David C. McFarland
Publikováno v:
Emu - Austral Ornithology. 96:181-188
Territorial non-breeding New Holland Honeyeaters Phylidonyris novaehollandiae were studied in an open forest in eastern Australia. During winter, birds maintained priority of access to nectar from Banksia inflorescences but the extent to which this u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1eec471b4a9b5d73b3dfd05115548794
https://doi.org/10.1071/mu9960181
https://doi.org/10.1071/mu9960181
Autor:
David C. McFarland
Publikováno v:
Emu - Austral Ornithology. 94:193-200
New Holland Honeyeaters Phylidonyris novaehollandiae occupying feeding territories during the nonbreeding season were studied in an open forest in northeastern New South Wales. The energy content of these territories fluctuated from day-to-day both n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcab70b2c1789e79b5a282a4d82414ae
https://doi.org/10.1071/mu9940193
https://doi.org/10.1071/mu9940193
Autor:
David C. McFarland, Kristi R. Harkins
Publikováno v:
Flow Cytometry in Drug Discovery and Development
The primary departmental goal of preclinical toxicology (a.k.a. safety assessment) in drug development is to identify and characterize drug-induced toxicity in test animals by using appropriate animal models. This is accomplished through a large numb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cc4588d775b0c04aa697188d2b1699f
https://doi.org/10.1002/9780470910085.ch6
https://doi.org/10.1002/9780470910085.ch6
Autor:
David C. McFarland, Kendall S. Frazier, Lauren A. Tierney, Marshall S. Scicchitano, Heath C. Thomas, Lester W. Schwartz, Rogely W. Boyce
Publikováno v:
Blood cells, moleculesdiseases. 40(3)
This study was designed to evaluate effects of specific p38 MAP kinase inhibition on gene and protein expression of essential hematopoietic cytokines in primary human bone marrow stromal cells (HBMSC) and to identify downstream transcription factors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eabca0dd52e7175d83363087f3401d5f
https://pubmed.ncbi.nlm.nih.gov/18093851
https://pubmed.ncbi.nlm.nih.gov/18093851