Zobrazeno 1 - 10
of 12
pro vyhledávání: '"David C. Litzinger"'
Autor:
Thea Norman, Tsotne Javahishvili, Stuart Bussell, David C. Litzinger, Stephanie Chu, Bruce E. Kimmel, Ricky Lieu, Sami Kaphle, Bee-Cheng Sim, Peter G. Schultz, Thomas L. Daniel, Mike Ong, Anna-Maria A. Hays Putnam, Zhenwei Maio, Ying Buechler, Richard D. DiMarchi, Ho Cho, Andrew R. Hoffman, Guillermo Viramontes, Paola Castiglioni, Douglas W. Axelrod, Becky Gc, Vadim Kraynov, Nick Knudsen
Publikováno v:
Proceedings of the National Academy of Sciences. 108:9060-9065
The ribosomal incorporation of nonnative amino acids into polypeptides in living cells provides the opportunity to endow therapeutic proteins with unique pharmacological properties. We report here the first clinical study of a biosynthetic protein pr
Autor:
Iwona Wala, Collins David S, Stephen Kaufman, Catherine L. Farrell, David C. Litzinger, Jeffrey M. Brown, Gwyneth Y. han
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1281:139-149
The present studies describe the biodistribution of cationic liposomes and cationic liposome/oligonucleotide complex following intravenous injection into mice via the tail vein. (111)In-diethylenetriaminepentaacetic acid stearylamide ((111)In-DTPA-SA
Autor:
Melissa A Woodward, David C. Litzinger, Ralph W. Niven, Wendy Laderach, K Lane Whitcomb, Lloyd D. Ralph, Michael J. Treuheit, Charles M. Ransone
Publikováno v:
Journal of Immunological Methods. 187:151-161
The chelating agent diethylenetriaminepentaacetic acid (DTPA) has been conjugated site-specifically to the N-terminus of recombinant human interleukin-2 (rhIL-2) by reaction with DTPA dianhydride at an initial pH of 6.0, thus demonstrating broader ap
Autor:
Leaf Huang, David C. Litzinger, Wolfgang Schatton, Joachim Bormann, Frauke Lehr, Petra Rudolph, Hans-Joachim Freisleben
Publikováno v:
Journal of Liposome Research. 5:215-223
Toxicity and biodistribution of negatively charged liposomes of the main phospholipid (MPL) from the archaebacterium Thermoplasma acidophilum were tested in mice. MPL liposomes with a diameter of 160–220 nm were prepared by extrusion through polyca
Autor:
David C. Litzinger, Leaf Huang
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1104:179-187
The biodistribution and immunotargetability of liposomes composed primarily of dioleoylphosphatidylethanolamine (DOPE) or dioleoylphosphatidylcholine (DOPC) in mice injected via the tail vein were examined and compared. The ganglioside GM1 (7 mol%) p
Autor:
Scott L. Lauren, Lloyd D. Ralph, Charles M. Ransone, Viswanatham Katta, Michael J. Treuheit, David C. Litzinger
Publikováno v:
Biochemistry. 34(14)
The chelating agent diethylenetriaminepentaacetic acid (DTPA) was conjugated site-specifically to the N-terminus of recombinant human granulocyte-colony-stimulating factor (rhG-CSF) by reaction of the protein with DTPA dianhydride at an initial pH of
Publikováno v:
Biochimica et biophysica acta. 1190(1)
Liposomes containing dioleoyl-N-(monomethoxypoly(ethylene glycol)succinyl)- phosphatidylethanolamine (PEG-PE), and of three characteristic sizes (d > 300 nm, d approximately 150-200 nm, and d < 70 nm), were prepared, injected into mice, and their bio
Autor:
David C. Litzinger, Leaf Huang
Publikováno v:
Biochimica et biophysica acta. 1127(3)
Relatively small liposomes (d less than 200 nm) composed of dioleoylphosphatidylethanolamine (DOPE) and cholesterol (Chol) and containing dioleoyl-N-(monomethoxypoly(ethylene glycol)succinyl)phosphatidylethanolamine (PEG-PE), with PEG of M(r) 5000 (P
Autor:
Leaf Huang, David C. Litzinger
Publikováno v:
Biochimica et biophysica acta. 1113(2)
II. Physical proper t ies of PE and PE l i r~somes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 202 A Polymorphic behavior of PE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Publikováno v:
Biochimica et biophysica acta. 1025(2)
The titratable, double-chain amphiphiles 1,2-dipalmitoyl-sn-3-succinylglycerol (1,2-DPSG), 1,2-dioleoyl-sn-3-succinylglycerol (1,2-DOSG) and 1,3-dipalmitoylsuccinylglycerol (1,3-DPSG) have been used in combination with phosphatidylethanolamine (PE) t