Zobrazeno 1 - 10
of 12
pro vyhledávání: '"David C. L. Jones"'
Publikováno v:
Environmental Health Perspectives
Chloroform is being administered to male Osborne-Mendel rats and to female B6C3F1 mice at concentrations of 0 (negative control), 200, 400, 900 or 1800 ppm in the drinking water. Matched control groups of both species receive a volume of water identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37b6d3c009e24ae78585020a06caaeba
http://europepmc.org/articles/PMC1569021
http://europepmc.org/articles/PMC1569021
Autor:
David C. L. Jones, Paul W. Houghton
Publikováno v:
Gastroenterology. 73:252-254
We have developed a test system for the evaluation of gastric secretion in the rhesus monkey on a chronic basis that does not require the usual restraining techniques. The system is characterized by ease of animal maintenance and handling, reliabilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e54f778062f3c6583fa630abcf903433
https://doi.org/10.1016/s0016-5085(19)32185-7
https://doi.org/10.1016/s0016-5085(19)32185-7
Autor:
David C. L. Jones, Ted A. Jorgenson, Vincent F. Simmon, Michael D. Waters, Ann D. Mitchell, R. Valencia, Shahbeg S. Sandhu, Neil E. Garrett, Kristien Mortelmans
Publikováno v:
Genetic Toxicology ISBN: 9781468443547
With a limited supply of arable land supporting an ever-increasing human population, the threat of crop loss to agricultural pests becomes continually more acute. Thus pesticides have become an essential component of modern agriculture. As competing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d0062d0805c2cb004d8e6042e5cc3bd
https://doi.org/10.1007/978-1-4684-4352-3_23
https://doi.org/10.1007/978-1-4684-4352-3_23
Publikováno v:
International journal of cancer. 27(2)
Dipentylnitrosamine (DPN), administered in the diet at a concentration of 2,000 ppm to Fischer-344 rats, produced hepatomas in 27% of both males and females within 8 weeks. Bile-duct carcinomas were also produced. All animals also showed liver nodula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cb630724367f467ab3f323e13ab7b95
https://pubmed.ncbi.nlm.nih.gov/7287219
https://pubmed.ncbi.nlm.nih.gov/7287219
Autor:
John S. Krebs, David C. L. Jones
The relationships between dose rate and radiation response were studied in sheep and in mice. For sheep, the LD 50/60 varies inversely with dose rate, even when the dose rate is several hundreds of R/hr. An initial exposure to as little as 10 R (midl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c95ef755c6de25bf857ffbd73069321
https://doi.org/10.21236/ada015187
https://doi.org/10.21236/ada015187
Publikováno v:
Toxicology. 2(3)
Hexachlorophene (HCP) was fed singly or paired with either aflatoxin B1 (AF), Aroclor 1254 (AR), or dieldrin (D) to Fischer-344 rats for 8 weeks beginning at 5 weeks of age. For HCP fed singly, there was no mortality at 400 ppm or less, 80% mortality
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92dcec6949b6e8dee351527cb609d483
https://pubmed.ncbi.nlm.nih.gov/4212172
https://pubmed.ncbi.nlm.nih.gov/4212172
Autor:
Frank Stack, Kristien Mortelmans, Ted A. Jorgenson, Shahbeg S. Sandhu, Vincent F. Simmon, Michael D. Waters, Ann D. Mitchell, David C. L. Jones, R. Valencia
Publikováno v:
Basic and Applied Mutagenesis ISBN: 9781468449785
The mutagenicity of fifteen insecticides, five fungicides, four herbicides, and an acaricide commonly used in Pakistan was evaluated by employing thirteen short-term bioassays. The genetic endpoints used included point or gene mutation, primary DNA d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f25e9766d6d9b48a35ec8a64a651bc1
https://doi.org/10.1007/978-1-4684-4976-1_14
https://doi.org/10.1007/978-1-4684-4976-1_14
Autor:
John S. Krebs, David C. L. Jones
Publikováno v:
Journal of Toxicology and Environmental Health. 3:1021-1021
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf2eea0cf517ec8c1e14561a3f3145ae
https://doi.org/10.1080/15287397709529636
https://doi.org/10.1080/15287397709529636
Publikováno v:
Radiation Research. 34:637
In a duration-of-life study, male Sprague-Dawley rats were exposed to 220 rads of fast neutrons as juveniles (1 month of age), young adults (3 months), middle-aged adults (10, 15 months), or old adults (21 months) and compared with their sham-irradia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25c457ff59a58ceb0b2396264710545d
https://doi.org/10.2307/3572508
https://doi.org/10.2307/3572508
Autor:
David C. L. Jones, John S. Krebs
Publikováno v:
Radiation Research. 51:374
Mice were exposed to gamma radiation from60 Co sources at 1750 R/h and at 190 R/h. The 30 day LD50 was 873 R at 1750 R/h and 1359 R at 190 R/h. Survival curves of bone-marrow colony-forming cells measured between 100 and 500 R had values of D0 of 90.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::845000d5828e375dbb5f1ce3507c90f2
https://doi.org/10.2307/3573616
https://doi.org/10.2307/3573616