Zobrazeno 1 - 10
of 14
pro vyhledávání: '"David C. J. Carpentier"'
Autor:
Janet E. Deane, william nd Gao, David C. J. Carpentier, Stephen C. Graham, Chen Gao, Geoffrey L. Smith
The morphogenesis of vaccinia virus (VACV, family Poxviridae), the smallpox vaccine, is a complex process involving multiple distinct cellular membranes and resulting in multiple different forms of infectious virion. Efficient release of enveloped vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18e580ddb9380a2ac4782bd75b874e12
https://www.repository.cam.ac.uk/handle/1810/331153
https://www.repository.cam.ac.uk/handle/1810/331153
Publikováno v:
PLoS Pathogens, Vol 11, Iss 3, p e1004723 (2015)
During vaccinia virus morphogenesis, intracellular mature virus (IMV) particles are wrapped by a double lipid bilayer to form triple enveloped virions called intracellular enveloped virus (IEV). IEV are then transported to the cell surface where the
Externí odkaz:
https://doaj.org/article/f72232468e924d2e9a847e32796e0552
Autor:
Gareth W Morgan, Michael Hollinshead, Brian J Ferguson, Brendan J Murphy, David C J Carpentier, Geoffrey L Smith
Publikováno v:
PLoS Pathogens, Vol 6, Iss 2, p e1000785 (2010)
Vaccinia virus (VACV) uses microtubules for export of virions to the cell surface and this process requires the viral protein F12. Here we show that F12 has structural similarity to kinesin light chain (KLC), a subunit of the kinesin-1 motor that bin
Externí odkaz:
https://doaj.org/article/0f8252ab83c347159bcb82075b3cb84e
Autor:
David C J, Carpentier, Michael S, Hollinshead, Helen A, Ewles, Stacey-Ann, Lee, Geoffrey L, Smith
Publikováno v:
The Journal of General Virology
Vaccinia virus produces two distinct infectious virions; the single-enveloped intracellular mature virus (IMV), which remains in the cell until cell lysis, and the double-enveloped extracellular enveloped virus (EEV), which mediates virus spread. The
Autor:
Brendan J. Murphy, Brian J. Ferguson, Gareth W. Morgan, David C. J. Carpentier, Michael Hollinshead, Geoffrey L. Smith
Publikováno v:
PLoS Pathogens
e1000785
PLoS Pathogens, Vol 6, Iss 2, p e1000785 (2010)
e1000785
PLoS Pathogens, Vol 6, Iss 2, p e1000785 (2010)
Vaccinia virus (VACV) uses microtubules for export of virions to the cell surface and this process requires the viral protein F12. Here we show that F12 has structural similarity to kinesin light chain (KLC), a subunit of the kinesin-1 motor that bin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::459e467e46b628850b8b5c1b6f005426
Publikováno v:
The Journal of General Virology
Egress of vaccinia virus from its host cell is mediated by the microtubule-associated motor kinesin-1, and three viral proteins, A36 and the F12/E2 complex, have been implicated in this process. Deletion of F12 expression causes a more severe reducti
Publikováno v:
The Journal of General Virology
Vaccinia virus (VACV) has two infectious forms called intracellular mature virus and extracellular enveloped virus (EEV). Two of the seven viral proteins in the EEV outer envelope, A33 and A34, are type II membrane glycoproteins that each interact wi
Autor:
Linda A. King, David C. J. Carpentier
Publikováno v:
Virologica Sinica. 24:227-242
The baculovirus P10 protein has always represented a mystery in the field of insect virology. Like the baculovirus polyhedrin protein it is expressed at high levels very late in infection. Homologues of the Autographa californica nucleopolyhedrovirus
Publikováno v:
Virology. 371(2):278-291
The role of the microtubule-associated P10 protein of baculoviruses is not yet understood. P10 has previously been linked with the formation of a number of cytoskeletal-like or cytoskeleton-associated structures in the nucleus and cytoplasm, thought
Autor:
James N. Hislop, Michael D.J. Parkinson, Nicholas D. Mazarakis, David C. J. Carpentier, Ioanna Eleftheriadou, Tarin A. Islam, Antonio Trabalza, Giampietro Schiavo
Publikováno v:
Journal of Biological Chemistry
Rabies pseudotyped lentiviral vectors have great potential in gene therapy, not least because of their ability to transduce neurons following their distal axonal application. However, very little is known about the molecular processes that underlie t