Zobrazeno 1 - 10
of 15
pro vyhledávání: '"David C. Eustice"'
Autor:
James W. Darrow, Aaron Bourret, Robert Desimone, Jin-Ming Xiong, Patricia Maciejewski, Seung H. Lee, David C. Eustice, Mihaela Diana Danca, Douglas A. Pippin, David R. Brittelli, Kropf Jeffrey E, Peter Blomgren, Melissa Hill-Drzewi, Kevin S. Currie, Lisa Elkin, Steven L. Gallion, Scott A. Mitchell
Publikováno v:
Bioorganicmedicinal chemistry letters. 19(24)
Inhibition of receptor tyrosine kinases (RTKs) such as vascular endothelial growth factor receptors (VEGFRs) and platelet-derived growth factor receptors (PDGFRs) has been validated by recently launched small molecules Sutent® and Nexavar®, both of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7202d556fa080f4e12292f4943f66c5
https://pubmed.ncbi.nlm.nih.gov/19879134
https://pubmed.ncbi.nlm.nih.gov/19879134
Publikováno v:
Mammalian genome : official journal of the International Mammalian Genome Society. 10(4)
Osteotesticular phosphatase (OST-PTPase) is a class III receptor-type tyrosine phosphatase (RPTPase). It has 10 tandem fibronectin III-like (FN-III) repeats in the extracellular region and two phosphatase domains in the intracellular region. The expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef0949b1ee1d8a6a5e1d07fa719b7b34
https://pubmed.ncbi.nlm.nih.gov/10087294
https://pubmed.ncbi.nlm.nih.gov/10087294
Autor:
Carl P. Ciosek, John R. Wetterau, Richard E. Gregg, Ying Chen, Scott A. Biller, Ching-Hsuen Chu, Thomas Harrity, Jamil Haris, David C. Eustice, Beverly Ricci, David A. Gordon, Cindy M. Brooks, John K. Dickson
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 93(21)
The microsomal triglyceride (TG) transfer protein (MTP) is a heterodimeric lipid transfer protein that catalyzes the transport of triglyceride, cholesteryl ester, and phosphatidylcholine between membranes. Previous studies showing that the proximal c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c853bd1f83b610470c878e92cf42b760
https://pubmed.ncbi.nlm.nih.gov/8876250
https://pubmed.ncbi.nlm.nih.gov/8876250
Autor:
Gordon King, Juergen Bajorath, Richard P. Darveau, Diane Hollenbaugh, William E. Harte, David C. Eustice, Alejandro Aruffo
Publikováno v:
Biochemistry. 33(6)
P-Selectin (CD62/GMP140/PADGEM) is an inducible cell-surface glycoprotein expressed by endothelial cells and platelets following stimulation by inflammatory mediators such as thrombin, histamine, or peroxides. P-Selectin mediates the binding of leuko
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6235e74aeb2502faaf9d39331454c1d8
https://pubmed.ncbi.nlm.nih.gov/7508745
https://pubmed.ncbi.nlm.nih.gov/7508745
Publikováno v:
Biochemical and Biophysical Research Communications. 150:965-971
Pulse labeling studies with Bacillus subtilis showed that DuP 721 inhibited protein synthesis. The IC50 of DuP 721 for protein synthesis was 0.25 micrograms/ml but it was greater than 32 micrograms/ml for RNA and DNA synthesis. In cell-free systems,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d80e6aa05a67bef2cd47dd291c46d0d
https://doi.org/10.1016/0006-291x(88)90723-1
https://doi.org/10.1016/0006-291x(88)90723-1
Autor:
David C. Eustice, James M. Wilhelm
Publikováno v:
Biochemistry. 23:1462-1467
A homologous in vitro method was developed from Tetrahymena for ribosomal A-site binding of aminoacyl-tRNA to poly(uridylic acid)-programmed ribosomes with very low error frequency. The reaction mixture pH was the crucial factor in the stable A-site
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5904567f2b4958fa46f8a35d71b6e56
https://doi.org/10.1021/bi00302a019
https://doi.org/10.1021/bi00302a019
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 161:143-154
One objective of this study was to determine the effects of N-hydroxy-2-acetylaminofluorene (N-OH-AAF) treatment on DNA synthesis in regenerating rat liver. Rats were subjected to a two-thirds hepatectomy followed 20 h later by i.p. injection of N-OH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ae2c81689f2a92a5ea6ab84ef2bda19
https://doi.org/10.1016/0027-5107(86)90005-9
https://doi.org/10.1016/0027-5107(86)90005-9
Publikováno v:
Plant Physiology. 67:1054-1058
Selenomethionine and methionine were compared as substrates for in vitro aminoacylation, ribosome binding, and peptide bond formation with preparations from wheat germ. Selenomethionine paralleled methionine in all steps of the translation process ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5601296a13e05d552afe99f59d0da3b4
https://doi.org/10.1104/pp.67.5.1054
https://doi.org/10.1104/pp.67.5.1054
Publikováno v:
Plant Physiology. 66:182-186
Vigna radiata polysomes efficiently incorporated [(75)Se]selenomethionine, [(14)C]methionine, and [(14)C]leucine in vitro. The optimal conditions for translation were determined to be 4.8 millimolar Mg(2+), 182 millimolar K(+), and pH 7.4. The rates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a21388b93a03543352c0ff0a7df5331
https://doi.org/10.1104/pp.66.1.182
https://doi.org/10.1104/pp.66.1.182
Publikováno v:
Journal of molecular biology. 188(2)
The five suppressors SUP35, SUP43, SUP44, SUP45 and SUP46, each mapping at a different chromosomal locus in the yeast Saccharomyces cerevisiae, suppress a wide range of mutations, including representatives of all three types of nonsense mutations, UA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11985953a85871b4e81bcaa9819b4e70
https://pubmed.ncbi.nlm.nih.gov/3522920
https://pubmed.ncbi.nlm.nih.gov/3522920