Zobrazeno 1 - 10
of 46
pro vyhledávání: '"David C. Binder"'
Autor:
Lijie Zhai, Erik Ladomersky, Kristen L. Lauing, Meijing Wu, Denise M. Scholtens, Rohan Savoor, Bin Zhang, Jennifer D. Wu, Craig Horbinski, Rimas V. Lukas, David C. Binder, Derek A. Wainwright
Publikováno v:
OncoImmunology, Vol 8, Iss 3 (2019)
Preclinical modeling and gene expression analyses have yielded distinct observations for the role of immune checkpoint, IDO1, in glioblastoma (GBM). Accordingly, our recent work differs with Garg et al. (2017) with respect to IDO1 among preclinical a
Externí odkaz:
https://doaj.org/article/4f3c72e704db4a8ca010fd1b67d431de
Autor:
Hans Schreiber, Donald A. Rowley, David H. Munn, Robert M. Hoffman, Ming Zhao, Christian Idel, Byron Burnette, Theodore Karrison, Yang-Xin Fu, James M. Slauch, Ping Yu, Ainhoa Arina, Boris Engels, David C. Binder
Immunogenic tumors grow progressively even when heavily infiltrated by CD8+ T cells. We investigated how to rescue CD8+ T-cell function in long-established immunogenic melanomas that contained a high percentage of endogenous PD-1+ tumor-specific CD8+
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b7aea1d18fbbfd533cd3b004403fce6
https://doi.org/10.1158/2326-6066.c.6548200.v1
https://doi.org/10.1158/2326-6066.c.6548200.v1
Autor:
Hans Schreiber, Donald A. Rowley, David H. Munn, Robert M. Hoffman, Ming Zhao, Christian Idel, Byron Burnette, Theodore Karrison, Yang-Xin Fu, James M. Slauch, Ping Yu, Ainhoa Arina, Boris Engels, David C. Binder
PDF file - 122K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8be637d9b1a0ae102719cd23ed33bc0
https://doi.org/10.1158/2326-6066.22536658
https://doi.org/10.1158/2326-6066.22536658
Autor:
Hans Schreiber, Donald A. Rowley, David H. Munn, Robert M. Hoffman, Ming Zhao, Christian Idel, Byron Burnette, Theodore Karrison, Yang-Xin Fu, James M. Slauch, Ping Yu, Ainhoa Arina, Boris Engels, David C. Binder
PDF file - 291K, Figure S1. A1-R SIINF preferentially accumulates in established B16-OVA tumors. Figure S2. A1-R SIINF induces systemic SIINF-specific CD8+ T cell proliferation. Figure S3. Weekly A1-R SIINF treatment leads to rejection of established
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55b0d63c84519fc855ff8f969b7d8d4d
https://doi.org/10.1158/2326-6066.22536661
https://doi.org/10.1158/2326-6066.22536661
Autor:
Derek A. Wainwright, David C. Binder, Rimas V. Lukas, Roger Stupp, C. David James, Leonidas C. Platanias, Ricky Patel, Tristin Tang, Beibei Jiang, Yong Liu, Wenfeng Gong, Fenglong Yu, Ye Liu, Xuebing Sun, Galina Gritsina, Denise M. Scholtens, Jun Qian, Kristen L. Lauing, Alicia Lenzen, Lijie Zhai, Erik Ladomersky
Purpose: Glioblastoma is the most aggressive primary brain tumor in adults with a median survival of 15–20 months. Numerous approaches and novel therapeutics for treating glioblastoma have been investigated in the setting of phase III clinical tria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fef54233c0af7b23ea9c8492872989d
https://doi.org/10.1158/1078-0432.c.6527303.v1
https://doi.org/10.1158/1078-0432.c.6527303.v1
Autor:
Derek A. Wainwright, Roger Stupp, Craig Horbinski, Charles D. James, Francis J. Giles, Jeffrey A. Sosman, David C. Binder, Priscilla K. Brastianos, Balázs Győrffy, Galina Gritsina, Matthew Genet, Meijing Wu, Kristen L. Lauing, Erik Ladomersky, Lijie Zhai
Description of Materials and Methods used to generate the novel IDO1-overexpressing U87 cell line, Western blotting, RT-PCR, cancer genome atlas analysis, as well as high performance liquid chromatography.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0519b7327be62db20559b6b56c112e0f
https://doi.org/10.1158/1078-0432.22469213
https://doi.org/10.1158/1078-0432.22469213
Autor:
Derek A. Wainwright, David C. Binder, Rimas V. Lukas, Roger Stupp, C. David James, Leonidas C. Platanias, Ricky Patel, Tristin Tang, Beibei Jiang, Yong Liu, Wenfeng Gong, Fenglong Yu, Ye Liu, Xuebing Sun, Galina Gritsina, Denise M. Scholtens, Jun Qian, Kristen L. Lauing, Alicia Lenzen, Lijie Zhai, Erik Ladomersky
Supplementary figures and associated legends Supplementary Figure 1. In vitro GBM cell IDO1 metabolism with or without treatment of interferon-gamma (IFNï�§ï€©ï€ and/or IDO1 enzyme inhibitor, BGB-5777. Supplemental Figure 2. Mouse and huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e1ed1eef1597d73c3fe3a56cc558799
https://doi.org/10.1158/1078-0432.22469624
https://doi.org/10.1158/1078-0432.22469624
Autor:
Derek A. Wainwright, Roger Stupp, Craig Horbinski, Charles D. James, Francis J. Giles, Jeffrey A. Sosman, David C. Binder, Priscilla K. Brastianos, Balázs Győrffy, Galina Gritsina, Matthew Genet, Meijing Wu, Kristen L. Lauing, Erik Ladomersky, Lijie Zhai
Description of Supplementary Tables 1-5 that support the expression and clinical relevance of IDO1 in grades II and III glioma, as well as GBM.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2332c3e7bebf670aea764df91787fc24
https://doi.org/10.1158/1078-0432.22469210.v1
https://doi.org/10.1158/1078-0432.22469210.v1
Autor:
Derek A. Wainwright, Roger Stupp, Craig Horbinski, Charles D. James, Francis J. Giles, Jeffrey A. Sosman, David C. Binder, Priscilla K. Brastianos, Balázs Győrffy, Galina Gritsina, Matthew Genet, Meijing Wu, Kristen L. Lauing, Erik Ladomersky, Lijie Zhai
Description of Supplementary Figures 1-9 that support the expression and clinical relevance of IDO1 in human GBM.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14e865efa6e1324fa537eb8f53dc7a4e
https://doi.org/10.1158/1078-0432.22469216
https://doi.org/10.1158/1078-0432.22469216
Autor:
Derek A. Wainwright, David C. Binder, Rimas V. Lukas, Roger Stupp, C. David James, Leonidas C. Platanias, Ricky Patel, Tristin Tang, Beibei Jiang, Yong Liu, Wenfeng Gong, Fenglong Yu, Ye Liu, Xuebing Sun, Galina Gritsina, Denise M. Scholtens, Jun Qian, Kristen L. Lauing, Alicia Lenzen, Lijie Zhai, Erik Ladomersky
Supplementary tables and associated legends Supplementary Table 1. Antibodies utilized for flow cytometry. Supplementary Table 2. Primers utilized for RT-PCR analysis Supplementary Table 3. Survival after treatment with BGB-5777, radiotherapy and/or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24cca7bf77c820591fd599d6dc750f7e
https://doi.org/10.1158/1078-0432.22469621.v1
https://doi.org/10.1158/1078-0432.22469621.v1