Zobrazeno 1 - 10
of 18
pro vyhledávání: '"David C. Whritenour"'
Autor:
Abhijit S. Bhat, David Tumelty, Javier Magano, Douglas Farrand, Jeffrey P. Haase, John J. Teixeira, John D. Rizzo, Mark T. Maloney, David C. Whritenour, Michael Lovdahl, Mark John Pozzo, Curt W. Bradshaw
Publikováno v:
Tetrahedron Letters. 53:1385-1389
An optimized and scalable synthesis of a novel analytical reagent for the determination of the number of active sites available for conjugation on a catalytic aldolase monoclonal antibody (mAb) is described. The original conditions suffered from lack
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7151c94699e92d250be592b396b2851b
https://doi.org/10.1016/j.tetlet.2012.01.016
https://doi.org/10.1016/j.tetlet.2012.01.016
Autor:
Dwight A Trieber, Jeffery G Saven, Ffrancon Williams, David C Whritenour, Paola Cimino, Saba M Mattar, Vincenzo Barone, Guo-Fei Chen, Paul H. Scudder
Publikováno v:
The Journal of Physical Chemistry B. 113:9026-9034
An integrated experimental and computational approach was used to compare the properties of representative molecules containing intrabridgehead nitrogen atoms with those of the corresponding radical cations issuing from one-electron oxidation with th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6e327cef52bffa01e6281ba036e99bf
https://doi.org/10.1021/jp902493e
https://doi.org/10.1021/jp902493e
Publikováno v:
Organic Process Research & Development. 13:324-330
Several synthetic approaches to a corticotropin-releasing factor (CRF) antagonist containing a tetrasubstituted pyridine were evaluated. In particular, nucleophilic aromatic substitutions on 2,4-dichloropyridine derivatives were attempted using 2,6-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae13385a437c0bf3e186be42afce71fc
https://doi.org/10.1021/op800266x
https://doi.org/10.1021/op800266x
Publikováno v:
Organic Process Research & Development. 11:1141-1146
The potential hazards from cyclopentadiene storage and use on kilogram scale are studied under adiabatic conditions. Cyclopentadiene, a reagent commonly used in organic synthesis, is known to spontaneously dimerize exothermically and thus should be s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ef3defe29e512f061c36cfadbb65a91
https://doi.org/10.1021/op6002727
https://doi.org/10.1021/op6002727
Autor:
Kathleen S. Zandi, William Kissel, Brian M. Andresen, Chiu Charles K, John Charles Kath, David C. Whritenour, Matthew Frank Brown, Tung Le, Z. Jane Li, Eric Dias, Richard A. Buzon, Michel Couturier, Bryan Li, John L. Tucker, V. John Jasys, Joanna Teresa Negri, Poss Christopher Stanley, Frank J. Urban
Publikováno v:
Organic Process Research & Development. 9:466-471
Process development for the synthesis of 2-quinoxalinecarboxamide, N-[(1S,2S,4R)-4-(aminocarbonyl)-1-[(3-fluorophenyl)methyl]-2,7-dihydroxy-7-methyloctyl] is described. An optimized and streamlined process starting from lactone 2 was developed: Lacto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2bfdf67bd0fea0a89f37efcd9381a33b
https://doi.org/10.1021/op050059w
https://doi.org/10.1021/op050059w
Autor:
Michael C. Wirtz, David C. Whritenour, Karl Ng, Robert A. Singer, Michael G. Vetelino, Jotham Wadsworth Coe, Enrique Vazquez, Paige Roanne Palmer Brooks, Stephane Caron, Harry H. Watson
Publikováno v:
Synthesis. 2004:1755-1758
Preparations of 2,3,4,5-tetrahydro-1,5-methano-1H-3-benzazepine (5) from benzonorbornadiene (1) by oxidative cleavage and reductive amination sequences were investigated. Osmium-mediated dihydroxylation of 1 followed by NaIO 4 cleavage, reductive ami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7ff1bf4325e7c104f5a9ca259eec29c
https://doi.org/10.1055/s-2004-829135
https://doi.org/10.1055/s-2004-829135
Publikováno v:
Journal of Chemical Research. 2006:478-480
A streamlined process for the synthesis of 3-amino-1-benzhydrylazetidine is described. Commercially available 1-benzhydrylazetidin-3-ol was reacted with methanesulfonyl chloride in the presence of triethylamine in acetonitrile, upon quench with water
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02a899c11398a4feef397322ff72500b
https://doi.org/10.3184/030823406777980583
https://doi.org/10.3184/030823406777980583
Publikováno v:
Organic Process Research & Development. 5:539-541
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1148750e3ee6873ce91fa394dd692756
https://doi.org/10.1021/op0100089
https://doi.org/10.1021/op0100089
Autor:
Peter Somfai, David C. Whritenour, John C. Roberts, Michael H. Nantz, Tadashi Tamura, Satoru Masamune, Masanori Kageyama
Publikováno v:
ChemInform. 22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aebbda06d0ae4e12b733303c8305b346
https://doi.org/10.1002/chin.199102369
https://doi.org/10.1002/chin.199102369
Publikováno v:
ChemInform. 25
Novel bridged phthalein dyes substituted with a diisopropylamide ortho to the bridge are stable at high pH; with a chromogenically active auxochrome ortho to the meso carbon, a hypsochromic shift, band narrowing, and an increased molar absorptivity o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::608bc129bf180f18bcacc7b9aaf472c1
https://doi.org/10.1002/chin.199430194
https://doi.org/10.1002/chin.199430194