Zobrazeno 1 - 10
of 21
pro vyhledávání: '"David C. Rishikof"'
Publikováno v:
Histochemistry and Cell Biology. 125:527-534
The repair of alveolar structures following endotracheal administration of porcine pancreatic elastase (PPE) to mice involves the coordinated deposition of new matrix elements. We determined the induction of the myofibroblast phenotype following elas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbcd020033488c72527c408422745c2f
https://doi.org/10.1007/s00418-005-0109-6
https://doi.org/10.1007/s00418-005-0109-6
Autor:
Ronald H. Goldstein, Edgar C. Lucey, David C. Rishikof, Donald E. Humphries, Daniel Bronsnick, Ping-Ping Kuang
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 33:371-377
Interstitial fibroblasts are an integral component of the alveolar wall. These cells produce matrix proteins that maintain the extracellular scaffold of alveolar structures. Emphysema is characterized by airspace enlargement resulting from the loss o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d6038f2d3704af7f8e4f76111dba0c5
https://doi.org/10.1165/rcmb.2004-0319oc
https://doi.org/10.1165/rcmb.2004-0319oc
Autor:
Xinfang Li, Lucy Liaw, Anthony W. O'Regan, David M. Serlin, David C. Rishikof, Margaret Goetschkes, Dennis A. Ricupero, J. A. Hayes, Geoffrey Whitley, Jeffrey S. Berman
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 286:L1311-L1318
Osteopontin is a multifunctional matricellular protein abundantly expressed during inflammation and repair. Osteopontin deficiency is associated with abnormal wound repair characterized by aberrant collagen fibrillogenesis in the heart and skin. Rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afbdcc08fdffdf11aa5a5da5a54a3e27
https://doi.org/10.1152/ajplung.00394.2003
https://doi.org/10.1152/ajplung.00394.2003
Publikováno v:
Journal of Cellular Biochemistry. 91:740-748
Fibrotic lung diseases are characterized by excess extracellular matrix production, in particular type I collagen. Phenylbutyrate (PB) is a non-toxic pharmacological compound that functions as a weak histone deacetylase inhibitor. In hepatic stellate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ec4d8d0c1278027e3a1ce31191a96d5
https://doi.org/10.1002/jcb.10742
https://doi.org/10.1002/jcb.10742
Publikováno v:
Journal of Cellular Biochemistry. 85:496-504
Transforming growth factor-β (TGF-β) and interleukin-4 (IL-4) have fibrogenic properties and induce extracellular matrix production in a variety of lung diseases. Connective tissue growth factor (CTGF) is a matrix signaling molecule stimulated by T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7692394f0a91f8bb13349b420dda3ebd
https://doi.org/10.1002/jcb.10144
https://doi.org/10.1002/jcb.10144
Autor:
Dennis A. Ricupero, Ronald H. Goldstein, Ping-Ping Kuang, David C. Rishikof, Christine F. Poliks
Publikováno v:
FEBS Letters. 506:15-21
We investigated the effect of the dietary flavonoid apigenin on myofibroblast function. We report that in myofibroblasts treated with apigenin, proliferation and basal levels of alpha1(I) collagen and alpha-smooth muscle actin mRNAs were markedly red
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0535241b7368bdf7dfccc9b9c483fd75
https://doi.org/10.1016/s0014-5793(01)02737-5
https://doi.org/10.1016/s0014-5793(01)02737-5
Autor:
David C. Rishikof, Ping-Ping Kuang, Ronald H. Goldstein, Kelly A. Cuttle, Dennis A. Ricupero, Christine F. Poliks
Publikováno v:
American Journal of Physiology-Cell Physiology. 281:C99-C105
We investigated the role of phosphatidylinositol 3-kinase (PI3K) in the expression of α1(I) collagen mRNA. We report that the basal level of α1(I) collagen mRNA was reduced when PI3K activity was inhibited by either LY-294002 or wortmannin. These P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f94fac5e4ddac04dfc93bd37212ae74
https://doi.org/10.1152/ajpcell.2001.281.1.c99
https://doi.org/10.1152/ajpcell.2001.281.1.c99
Autor:
Joseph Loscalzo, Samuel I. Hammerman, Gilbert R. Upchurch, Katherine Hendra, Elizabeth S. Klings, Harrison W. Farber, David C. Rishikof
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 277:H1579-H1592
Acute chest syndrome (ACS) is the most common form of acute pulmonary disease associated with sickle cell disease. To investigate the possibility that alterations in endothelial cell (EC) production and metabolism of nitric oxide (NO) products might
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c66f18cbb230c9efad072dc2a1118a0a
https://doi.org/10.1152/ajpheart.1999.277.4.h1579
https://doi.org/10.1152/ajpheart.1999.277.4.h1579
Publikováno v:
Journal of Cellular Biochemistry. 75:130-137
Fibrotic lung diseases are characterized by excessive deposition of type I collagen. Amino acid availability regulates type I collagen mRNA levels in quiescent human lung fibroblasts. In these studies, the effect of amino acid availability on type I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4acaa0a7d69204df9412e9b358ae570b
https://doi.org/10.1002/(sici)1097-4644(19991001)75:1<130::aid-jcb13>3.0.co
https://doi.org/10.1002/(sici)1097-4644(19991001)75:1<130::aid-jcb13>3.0.co
Publikováno v:
Texas Heart Institute journal. 40(4)
In patients who present with pulmonary embolism, right-heart thrombus is a rare condition that is associated with increased mortality rates, compared with pulmonary embolism alone. Thrombolytic therapy has been associated with a survival benefit in p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bcc34a1a4737d41e1f8caa40cf664060
https://pubmed.ncbi.nlm.nih.gov/24082387
https://pubmed.ncbi.nlm.nih.gov/24082387