Zobrazeno 1 - 6
of 6
pro vyhledávání: '"David C.‐Y. Lu"'
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Red cells from LK sheep represent an important paradigm for control of KCl cotransport activity, as well as being important to sheep erythroid function. A previous report (Godart et al., 1997) suggested that autologous plasma markedly inhibits red ce
Externí odkaz:
https://doaj.org/article/bc71a55879c74ff283db34029dc89857
Autor:
David C.-Y. Lu, Rasiqh Wadud, Anke Hannemann, David C. Rees, John N. Brewin, John Stanley Gibson
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Red cells from patients with sickle cell anaemia (SCA) contain the abnormal haemoglobin HbS. Under hypoxic conditions, HbS polymerises and causes red cell sickling, a rise in intracellular Ca2+ and exposure of phosphatidylserine (PS). These changes m
Externí odkaz:
https://doaj.org/article/ebe75d5e74ca4d73a1ce09566d93a87d
Autor:
Halima Al Balushi, Kobina Dufu, David C. Rees, John N. Brewin, Anke Hannemann, Donna Oksenberg, David C.‐Y. Lu, John S. Gibson
Publikováno v:
Physiological Reports, Vol 7, Iss 6, Pp n/a-n/a (2019)
Abstract Sickle cell anemia (SCA) is one of the commonest severe inherited disorders. Nevertheless, effective treatments remain inadequate and novel ones are avidly sought. A promising advance has been the design of novel compounds which react with h
Externí odkaz:
https://doaj.org/article/9c3d3183d1f64aec9f3a922b887157e1
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Frontiers in Physiology
Frontiers in Physiology
Red cells from patients with sickle cell anaemia (SCA) contain the abnormal haemoglobin HbS. Under hypoxic conditions, HbS polymerises and causes red cell sickling, a rise in intracellular Ca2+ and exposure of phosphatidylserine (PS). These changes m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29d819691c4eaf9af195d22ab9c53435
Autor:
John S. Gibson, Anke Hannemann, Rasiqh Wadud, David C. Rees, David C.-Y. Lu, John N. Brewin, Philip S. Low
Publikováno v:
Pflugers Archiv
Abnormal activity of red cell KCl cotransport (KCC) is involved in pathogenesis of sickle cell anaemia (SCA). KCC-mediated solute loss causes shrinkage, concentrates HbS, and promotes HbS polymerisation. Red cell KCC also responds to various stimuli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04dc52fd818626a922f33e9c3987a921
Autor:
John N. Brewin, Kobina Dufu, David C. Rees, David C.-Y. Lu, Anke Hannemann, Halima Al Balushi, Donna Oksenberg, John S. Gibson
Publikováno v:
Physiological Reports, Vol 7, Iss 6, Pp n/a-n/a (2019)
Physiological Reports
Physiological Reports
Sickle cell anemia (SCA) is one of the commonest severe inherited disorders. Nevertheless, effective treatments remain inadequate and novel ones are avidly sought. A promising advance has been the design of novel compounds which react with hemoglobin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c61cca9a08ae56919ea574805bcffc8
https://doi.org/10.14814/phy2.14027
https://doi.org/10.14814/phy2.14027