Zobrazeno 1 - 10
of 41
pro vyhledávání: '"David C Rinker"'
Autor:
David C. Rinker, Thomas J. C. Sauters, Karin Steffen, Adiyantara Gumilang, Huzefa A. Raja, Manuel Rangel-Grimaldo, Camila Figueiredo Pinzan, Patrícia Alves de Castro, Thaila Fernanda dos Reis, Endrews Delbaje, Jos Houbraken, Gustavo H. Goldman, Nicholas H. Oberlies, Antonis Rokas
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-16 (2024)
Abstract Fungal pathogens exhibit extensive strain heterogeneity, including variation in virulence. Whether closely related non-pathogenic species also exhibit strain heterogeneity remains unknown. Here, we comprehensively characterized the pathogeni
Externí odkaz:
https://doaj.org/article/c85380d1268244839d8888e033552685
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28774 (2011)
BackgroundInsect odorant receptors (ORs) function as odorant-gated ion channels consisting of a conventional, odorant-binding OR and the Orco coreceptor. While Orco can function as a homomeric ion channel, the role(s) of the conventional OR in hetero
Externí odkaz:
https://doaj.org/article/74ef5fd23ceb4e3b9cf240e2ea6cae9b
Autor:
Souhrid Mukherjee, Thomas A. Cassini, Ningning Hu, Tao Yang, Bian Li, Wangzhen Shen, Christopher W. Moth, David C. Rinker, Jonathan H. Sheehan, Joy D. Cogan, John H. Newman, Rizwan Hamid, Robert L. Macdonald, Dan M. Roden, Jens Meiler, Georg Kuenze, John A. Phillips, John A. Capra
Publikováno v:
HGG Advances, Vol 3, Iss 4, Pp 100131- (2022)
Summary: Whole-exome sequencing (WES) in the clinic has identified several rare monogenic developmental and epileptic encephalopathies (DEE) caused by ion channel variants. However, WES often fails to provide actionable insight for rare diseases, suc
Externí odkaz:
https://doaj.org/article/80f15d97adae43d6b743ecd6b1a9570f
Autor:
Yan Yan, Leah T. Sigle, David C. Rinker, Tania Y. Estévez-Lao, John A. Capra, Julián F. Hillyer
Publikováno v:
Open Biology, Vol 12, Iss 9 (2022)
The immune and circulatory systems of animals are functionally integrated. In mammals, the spleen and lymph nodes filter and destroy microbes circulating in the blood and lymph, respectively. In insects, immune cells that surround the heart valves (o
Externí odkaz:
https://doaj.org/article/b96bac3478e84ecab7ca82a3ac8016eb
Autor:
John G. Gibbons, Paolo D’Avino, Shu Zhao, Grace W. Cox, David C. Rinker, Jarrod R. Fortwendel, Jean-Paul Latge
Publikováno v:
Frontiers in Fungal Biology, Vol 3 (2022)
Aspergillus fumigatus is a potentially deadly opportunistic human pathogen. A. fumigatus has evolved a variety of mechanisms to evade detection by the immune system. For example, the conidium surface is covered in a layer of 1,8-dihydroxynaphthalene
Externí odkaz:
https://doaj.org/article/097dab6717fb417bbfd2d2de798b7ae4
Autor:
Shu Zhao, Adela Martin-Vicente, Ana Cristina Colabardini, Lilian Pereira Silva, David C. Rinker, Jarrod R. Fortwendel, Gustavo Henrique Goldman, John G. Gibbons
Publikováno v:
Microbiology Spectrum. 10
This is one of the first studies to apply genomewide association (GWA) analysis to identify genes involved in an Aspergillus fumigatus phenotype. A. fumigatus is an opportunistic fungal pathogen that causes hundreds of thousands of infections and ~10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72d34d82bc63a01203deceb1c8aa0a85
https://doi.org/10.1128/spectrum.00519-22
https://doi.org/10.1128/spectrum.00519-22
Autor:
null Yan Yan, null Leah T. Sigle, null David C. Rinker, null Tania Y. Estévez-Lao, null John A. Capra, null Julián F. Hillyer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1273385fa76beeea949f42766607e6c4
https://doi.org/10.1098/rsob.220111/v3/response1
https://doi.org/10.1098/rsob.220111/v3/response1
Autor:
Rory J. Tinker, Tiffany Guess, David C. Rinker, Jonathan H. Sheehan, Daniel Lubarsky, Binu Porath, Mackenzie Mosera, Ping Mayo, Emily Solem, Laura A. Lee, Asha Sarma, Jennifer Brault
Publikováno v:
Molecular geneticsgenomic medicine. 10(12)
A de novo, pathogenic, missense variant in UBTF, c.628GA p.Glu210Lys, has been described as the cause of an emerging neurodegenerative disorder, Childhood-Onset Neurodegeneration with Brain Atrophy (CONDBA). The p.Glu210Lys alteration yields a positi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06376d365dfa3701c7140600701c4b36
https://pubmed.ncbi.nlm.nih.gov/36106513
https://pubmed.ncbi.nlm.nih.gov/36106513
Autor:
David C. Rinker, Evonne McArthur, Emily Hodges, Douglas Shaw, Corinne N. Simonti, John A. Capra
Publikováno v:
Nature ecology & evolution
Neanderthal ancestry remains across modern Eurasian genomes, and introgressed sequences influence diverse phenotypes. Here we demonstrate that introgressed sequences reintroduced thousands of ancestral alleles that were lost in Eurasian populations p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df442c4edea57c41da245cee542596ef
https://doi.org/10.1038/s41559-020-1261-z
https://doi.org/10.1038/s41559-020-1261-z
Publikováno v:
BMC Biology, Vol 18, Iss 1, Pp 1-21 (2020)
BMC Biology
BMC Biology
Background Neural circuits are initially assembled during development when neurons synapse with potential partners and later refined as appropriate connections stabilize into mature synapses while inappropriate contacts are eliminated. Disruptions to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46c600749e0eea0bacf9cc9410d2add2
http://link.springer.com/article/10.1186/s12915-020-00817-0
http://link.springer.com/article/10.1186/s12915-020-00817-0