Zobrazeno 1 - 4
of 4
pro vyhledávání: '"David C Rawling"'
Publikováno v:
eLife, Vol 4 (2015)
Retinoic acid-inducible gene I (RIG-I) initiates a rapid innate immune response upon detection and binding to viral ribonucleic acid (RNA). This signal activation occurs only when pathogenic RNA is identified, despite the ability of RIG-I to bind end
Externí odkaz:
https://doaj.org/article/fd873084b8de407980eb3f33e4a8b35b
Publikováno v:
Clinical Chemistry. 68:550-560
Background Early and accurate diagnosis of acute infections can help minimize the overprescription of antibiotics and improve patient outcomes. Discrimination between bacterial and viral etiologies in acute infection based on changes in host gene exp
Autor:
Simone A Thair, Yudong He, Yehudit Hasin-Brumshtein, Suraj Sakaram, Rushika R Pandya, Jiaying Toh, David C Rawling, Melissa Remmel, Sabrina Coyle, George Dalekos, Ioannis Koutsodimitropoulos, Glykeria Vlachogianni, Eleni Gkeka, Eleni Karakike, Georgia Damoraki, Nikolaos Antonakos, Medical Degree, Purvesh Khatri, Evangelos J Giamarellos, Timothy Sweeney
Publikováno v:
Open Forum Infectious Diseases
Background COVID-19 is a pandemic caused by the SARS-CoV-2 virus that shares and differs in clinical characteristics of known viral infections. Methods We obtained RNAseq profiles of 62 prospectively enrolled COVID-19 patients and 24 healthy controls
Autor:
ljubomir Buturovic, Purvesh Khatri, Benjamin Tang, Kevin Lai, Win Sen Kuan, Mark Gillett, Rahul Santram, Maryam Shojaei, Raquel Almansa, Jose Nieto, Sonsoles Muñoz, Carmen Herrero, Nikolaos Antonakos, Medical Degree, Panayiotis Koufargyris, Marina Kontogiorgi, Georgia Damoraki, Oliver Liesenfeld, James Wacker, Uros Midic, Roland Luethy, David C Rawling, Melissa Remmel, Sabrina Coyle, Evangelos J Giamarellos, Timothy Sweeney
Publikováno v:
Open Forum Infectious Diseases
Background While major progress has been made to establish diagnostic tools for the diagnosis of SARS-CoV-2 infection, determining the severity of COVID-19 remains an unmet medical need. With limited hospital resources, gauging severity would allow f