Zobrazeno 1 - 10
of 42
pro vyhledávání: '"David C A, Gaboriau"'
Autor:
Richard J. Hewitt, Franz Puttur, David C. A. Gaboriau, Frédéric Fercoq, Maryline Fresquet, William J. Traves, Laura L. Yates, Simone A. Walker, Philip L. Molyneaux, Samuel V. Kemp, Andrew G. Nicholson, Alexandra Rice, Edward Roberts, Rachel Lennon, Leo M. Carlin, Adam J. Byrne, Toby M. Maher, Clare M. Lloyd
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Aberrant expansion of KRT5+ basal cells in the distal lung accompanies progressive alveolar epithelial cell loss and tissue remodelling during fibrogenesis in idiopathic pulmonary fibrosis (IPF). The mechanisms determining activity of KRT5+
Externí odkaz:
https://doaj.org/article/c6117e8de91842c6bbf2409cf0b50247
Autor:
Nupur Kohli, Konstantinos Theodoridis, Thomas A. G. Hall, Inigo Sanz-Pena, David C. A. Gaboriau, Richard J. van Arkel
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Introduction: Preclinical assessment of bone remodelling onto, into or around novel implant technologies is underpinned by a large live animal testing burden. The aim of this study was to explore whether a lab-based bioreactor model could provide sim
Externí odkaz:
https://doaj.org/article/bf1a8fee1d874b25805cd90e9134ffa6
Autor:
Olivier Mercey, Corinne Kostic, Eloïse Bertiaux, Alexia Giroud, Yashar Sadian, David C A Gaboriau, Ciaran G Morrison, Ning Chang, Yvan Arsenijevic, Paul Guichard, Virginie Hamel
Publikováno v:
PLoS Biology, Vol 20, Iss 6, p e3001649 (2022)
Inherited retinal degeneration due to loss of photoreceptor cells is a leading cause of human blindness. These cells possess a photosensitive outer segment linked to the cell body through the connecting cilium (CC). While structural defects of the CC
Externí odkaz:
https://doaj.org/article/324b3bd946084b33b93c62af5b632046
Autor:
Sabrina Yahiya, Sarah Jordan, Holly X Smith, David C A Gaboriau, Mufuliat T Famodimu, Farah A Dahalan, Alisje Churchyard, George W Ashdown, Jake Baum
Publikováno v:
PLoS Pathogens, Vol 18, Iss 2, p e1010276 (2022)
Formation of gametes in the malaria parasite occurs in the midgut of the mosquito and is critical to onward parasite transmission. Transformation of the male gametocyte into microgametes, called microgametogenesis, is an explosive cellular event and
Externí odkaz:
https://doaj.org/article/1515374a49094d58be725d3231734c25
Autor:
Khondoker M. Akram, Laura L. Yates, Róisín Mongey, Stephen Rothery, David C. A. Gaboriau, Jeremy Sanderson, Matthew Hind, Mark Griffiths, Charlotte H. Dean
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
The process of alveologenesis is incompletely understood, partly due to the lack of applicable real-time imaging methods. Here the authors describe the process of alveologenesis and the behaviour of epithelial cells in real-time, using widefield micr
Externí odkaz:
https://doaj.org/article/24ffe26043ce43fea34a19872584d905
Autor:
Sek-Shir Cheong, Khondoker M. Akram, Carlos Matellan, Sally Yunsun Kim, David C. A. Gaboriau, Matthew Hind, Armando E. del Río Hernández, Mark Griffiths, Charlotte H. Dean
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
VANGL2 is a component of the planar cell polarity (PCP) pathway, which regulates tissue polarity and patterning. The Vangl2Lp mutation causes lung branching defects due to dysfunctional actomyosin-driven morphogenesis. Since the actomyosin network re
Externí odkaz:
https://doaj.org/article/07c66229bd7e4222afdaf63adbfcebd6
Autor:
Anna P. Constantinou, Valeria Nele, James J. Doutch, Joana S. Correia, Roman V. Moiseev, Martina Cihova, David C. A. Gaboriau, Jonathan Krell, Vitaliy V. Khutoryanskiy, Molly M. Stevens, Theoni K. Georgiou
Publikováno v:
Macromolecules. 55:1783-1799
Thermoresponsive polymers with the appropriate structure form physical networks upon changes in temperature, and they find utility in formulation science, tissue engineering, and drug delivery. Here, we report a cost-effective biocompatible alternati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4098e7ab0543b6e84d447d126bb39efa
https://doi.org/10.1021/acs.macromol.1c02123
https://doi.org/10.1021/acs.macromol.1c02123
Autor:
Richard J. Hewitt, Franz Puttur, David C. A. Gaboriau, Frédéric Fercoq, Maryline Fresquet, William J. Traves, Laura L. Yates, Simone A. Walker, Philip L. Molyneaux, Samuel V. Kemp, Andrew G. Nicholson, Alexandra Rice, Rachel Lennon, Leo M. Carlin, Adam J. Byrne, Toby M. Maher, Clare M. Lloyd
Aberrant expansion of KRT5+basal cells in the distal lung accompanies progressive alveolar epithelial cell loss and tissue remodelling during fibrogenesis in idiopathic pulmonary fibrosis (IPF). The mechanisms determining activity of KRT5+cells in IP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb459570fb19996ca83f848dc3537ed1
https://doi.org/10.1101/2022.12.16.520808
https://doi.org/10.1101/2022.12.16.520808
Autor:
Patrik R. Jones, Jacob G. Bundy, David C. A. Gaboriau, Giorgio Perin, Virag Sagi-Kiss, Tyler Fletcher, Mathew R. Carey
Publikováno v:
Plant, Cell & Environment. 44:1885-1907
Nitrogen sources are all converted into ammonium/ia as a first step of assimilation. It is reasonable to expect that molecular components involved in the transport of ammonium/ia across biological membranes connect with the regulation of both nitroge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f041f167dee9b9dafcb825efed32d753
https://doi.org/10.1111/pce.14034
https://doi.org/10.1111/pce.14034
Autor:
Martin Priessner, Jonathan R. Chubb, Arlo Sheridan, Ramon Vilar, Tchern Lenn, Uri Manor, David C. A. Gaboriau, Romain F. Laine
The development of high-resolution microscopes has made it possible to investigate cellular processes in 4D (3D over time). However, observing fast cellular dynamics remains challenging as a consequence of photobleaching and phototoxicity. These issu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6520d02267d71da1a5a3418ce4feda22
https://doi.org/10.1101/2021.11.02.466664
https://doi.org/10.1101/2021.11.02.466664