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of 9
pro vyhledávání: '"David C, Whitacre"'
Autor:
David C Whitacre, Diego A Espinosa, Cory J Peters, Joyce E Jones, Amy E Tucker, Darrell L Peterson, Fidel P Zavala, David R Milich
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0124856 (2015)
In order to design P. falciparum preerythrocytic vaccine candidates, a library of circumsporozoite (CS) T and B cell epitopes displayed on the woodchuck hepatitis virus core antigen (WHcAg) VLP platform was produced. To test the protective efficacy o
Externí odkaz:
https://doaj.org/article/25cb1a6c7c5a458393e2df575523d2d4
Autor:
Lars Frelin, Janice Hughes, Byung O. Lee, David R. Milich, Won-Keun Kim, Cory J. Peters, David C. Whitacre, Joyce E. Jones
Publikováno v:
Immunology. 134:434-447
Regulatory T (Treg) cells represent one of the main mechanisms of regulating self-reactive immune cells. Treg cells are thought to play a role in down-regulating immune responses to self or allogeneic antigens in the periphery. Although the function
Autor:
Gary Van Nest, Darrell L. Peterson, David R. Milich, Roderick Tang, Joyce E. Jones, Michael P. McCarthy, Heather Lawlor, Jasmine Kaur, David C. Whitacre, Jeanne H. Schickli, Cory J. Peters
Publikováno v:
The Journal of clinical investigation. 125(4)
Respiratory syncytial virus (RSV) is the most common cause of serious viral bronchiolitis in infants, young children, and the elderly. Currently, there is not an FDA-approved vaccine available for RSV, though the mAb palivizumab is licensed to reduce
Publikováno v:
Expert review of vaccines. 8(11)
The first virus-like particle to be tested for use as a vaccine carrier was based on the hepatitis B virus nucleocapsid protein. This viral subunit, while not infectious on its own, is a 36-nm particle that is highly immunogenic during a natural infe
Autor:
Joyce E. Jones, Byung O. Lee, David R. Milich, David C. Whitacre, Lars Frelin, Bryan Darsow, Janice Hughes, Darrell L. Peterson, Matti Sällberg, Amy E. Tucker, Cory J. Peters
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 182(11)
Previous studies demonstrated that the primary APCs for the hepatitis B core Ag (HBcAg) were B cells and not dendritic cells (DC). We now report that splenic B1a and B1b cells more efficiently present soluble HBcAg to naive CD4+ T cells than splenic
Autor:
David C. Whitacre, Jean-Noel Billaud, Therese Wahlström, Lars Frelin, Amy E. Tucker, Byung O. Lee, Joyce E. Jones, David R. Milich, Darrell L. Peterson, Janice Hughes, Cory J. Peters
Publikováno v:
Journal of virology. 83(3)
Hepatitis B virus (HBV) expresses two structural forms of the nucleoprotein, the intracellular nucleocapsid (hepatitis core antigen [HBcAg]) and the secreted nonparticulate form (hepatitis e antigen [HBeAg]). The aim of this study was to evaluate the
Autor:
David C, Whitacre, Sanjay, Chauhan, Tracy, Davis, Debra, Gordon, Anne E, Cress, Roger L, Miesfeld
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 13(1)
To better understand androgen action in normal prostate cells, we characterized the androgen growth response of an immortalized nontumorigenic rat prostate cell line called CA25 that had been stably transfected with androgen receptor (AR) cDNA. Surpr
Publikováno v:
Endocrine. 15(1)
Androgen receptor (AR) and glucocorticoid receptor (GR) influence distinct physiologic responses in steroid-responsive cells despite their shared ability to selectively bind in vitro to the same canonical DNA sequence (TGTTCT). While the DNA-binding
Autor:
David Whitacre, Tony R. Reid, Farah Hedjran, Charles E. Prussak, Thomas J. Kipps, Ingo G.H. Schmidt-Wolf, David C. Whitacre
Publikováno v:
Blood. 106:2109-2109
Adenovirus (Ad) vectors have been used to introduce genetic material into mammalian cells for gene-expression studies and/or gene therapy. Ad serotypes 2 and 5, the most widely used Ad virus vectors, belong to the group C adenoviruses, which bind to