Zobrazeno 1 - 10 of 87 pro vyhledávání: '"David C, Montrose"'
1
Akademický článek
Metabolic regulation of the mitochondrial immune checkpoint
Autor: David C. Montrose, Suchandrima Saha, Lorenzo Galluzzi
Publikováno v: OncoImmunology, Vol 13, Iss 1 (2024)
Disrupting mitochondrial function in malignant cells is a promising strategy to enhance anticancer immunity. We have recently demonstrated that depriving colorectal cancer cells of serine results in mitochondrial dysfunction coupled with the cytosoli
Externí odkaz: https://doaj.org/article/c995b12760714975a41da1f30fab3e05
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2
Akademický článek
Anti-tumor effects of an ID antagonist with no observed acquired resistance
Autor: Paulina M. Wojnarowicz, Marta Garcia Escolano, Yun-Han Huang, Bina Desai, Yvette Chin, Riddhi Shah, Sijia Xu, Saurabh Yadav, Sergey Yaklichkin, Ouathek Ouerfelli, Rajesh Kumar Soni, John Philip, David C. Montrose, John H. Healey, Vinagolu K. Rajasekhar, William A. Garland, Jeremy Ratiu, Yuan Zhuang, Larry Norton, Neal Rosen, Ronald C. Hendrickson, Xi Kathy Zhou, Antonio Iavarone, Joan Massague, Andrew J. Dannenberg, Anna Lasorella, Robert Benezra
Publikováno v: npj Breast Cancer, Vol 7, Iss 1, Pp 1-17 (2021)
Abstract ID proteins are helix-loop-helix (HLH) transcriptional regulators frequently overexpressed in cancer. ID proteins inhibit basic-HLH transcription factors often blocking differentiation and sustaining proliferation. A small-molecule, AGX51, t
Externí odkaz: https://doaj.org/article/fcc94ce778e043e9991e8da7d30777e4
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5
Supplementary Figure 2 from Metabolic Profiling, a Noninvasive Approach for the Detection of Experimental Colorectal Neoplasia
Autor: Andrew J. Dannenberg, Kotha Subbaramaiah, Edward D. Karoly, Rhonda K. Yantiss, Levy Kopelovich, Xi Kathy Zhou, David C. Montrose
muPDF file - 102K, Supplementary Figure 2. Canonical pathways affected in tumor tissue. Metabolites that were altered in tumor tissue vs. normal mucosa were analyzed by IPA and significantly affected canonical pathways are shown.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b741a1ebcf2a6e87a842c2be61a752d
https://doi.org/10.1158/1940-6207.22524723.v1
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6
Data from Celecoxib Alters the Intestinal Microbiota and Metabolome in Association with Reducing Polyp Burden
Autor: Andrew J. Dannenberg, Eric G. Pamer, Robert Benezra, Lilan Ling, Chen S. Suen, Edward D. Karoly, Nitai D. Leve, Steven S. Gross, Rhonda K. Yantiss, Erika Sue, Erin M. McNally, Xi Kathy Zhou, David C. Montrose
Treatment with celecoxib, a selective COX-2 inhibitor, reduces formation of premalignant adenomatous polyps in the gastrointestinal tracts of humans and mice. In addition to its chemopreventive activity, celecoxib can exhibit antimicrobial activity.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ae7ff1d318327c29025450d37c74f90a
https://doi.org/10.1158/1940-6207.c.6547562.v1
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8
Supplementary Table 2 from Metabolic Profiling, a Noninvasive Approach for the Detection of Experimental Colorectal Neoplasia
Autor: Andrew J. Dannenberg, Kotha Subbaramaiah, Edward D. Karoly, Rhonda K. Yantiss, Levy Kopelovich, Xi Kathy Zhou, David C. Montrose
PDF file - 68K, The identity and effect size of changes (AOM vs. saline-treated mice) based on log transformed data are shown for biochemicals whose changes are significant in feces and colorectum, plasma and colorectum and all 3 matrices, 7 weeks af
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70e8e0c8f9bf78971f8ca461c7e0296a
https://doi.org/10.1158/1940-6207.22524714
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