Zobrazeno 1 - 7
of 7
pro vyhledávání: '"David Burgenson"'
Autor:
James F, Zawada, David, Burgenson, Gang, Yin, Trevor J, Hallam, James R, Swartz, Robert D, Kiss
Publikováno v:
Current Opinion in Biotechnology. 76:102719
Cell-free protein synthesis (CFPS) technologies have grown from lab-scale research tools to biopharmaceutical production at the Good Manufacturing Practice manufacturing scale. Multiple human clinical trials are in progress with CFPS-based products.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb7076dfbff961d7cb9365abae095b11
https://doi.org/10.1016/j.copbio.2022.102719
https://doi.org/10.1016/j.copbio.2022.102719
Autor:
Gregory L. Szeto, Govind Rao, Xudong Ge, Yordan Kostov, David Burgenson, Leah Tolosa, Jonathan Linton
Publikováno v:
ACS synthetic biology. 9(8)
Historically, some of the first cell-free protein expression systems studied in vitro translation in various human blood cells. However, because of limited knowledge of eukaryotic translation and the advancement of cell line development, interest in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d89c4ce8824d2877a9c235498764c8c7
https://pubmed.ncbi.nlm.nih.gov/32698572
https://pubmed.ncbi.nlm.nih.gov/32698572
Autor:
Lynn Wong, Sevda Deldari, Douglas D. Frey, Benjamin Punshon-Smith, Abhay Andar, Antonio Moreira, Mathangi Gopalakrishnan, Joseph Piegols, Shayan Borhani, Xudong Ge, Isabel L. Jackson, Govind Rao, Leah Tolosa, Erick Gutierrez, Rajani Adiga, Chandrasekhar Gurramkonda, Chelsea Wagner, Mike Tolosa, Diana Newman, Andrew Zodda, Yordan Kostov, Yang Liu, David Burgenson, Zeljko Vujaskovic
Publikováno v:
Biotechnology Progress. 36
Protein therapeutics, also known as biologics, are currently manufactured at centralized facilities according to rigorous protocols. The manufacturing process takes months and the delivery of the biological products needs a cold chain. This makes it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a9acd3dbaa40232e491246fb02e7d0d
https://doi.org/10.1002/btpr.2970
https://doi.org/10.1002/btpr.2970
Autor:
Abhay Andar, Md-Sadique Hasan, Venkatesh Srinivasan, Mustafa Al-Adhami, Erick Gutierrez, David Burgenson, Xudong Ge, Leah Tolosa, Yordan Kostov, Govind Rao
Publikováno v:
Analytical chemistry. 91(17)
As nonbiodegradable plastics continue to pollute our land and oceans, countries are starting to ban the use of single-use plastics. In this paper, we demonstrated the fabrication of wood-based microfluidic devices and their adaptability for single-us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28cefe6e940166a56612314b9761d125
https://pubmed.ncbi.nlm.nih.gov/31361950
https://pubmed.ncbi.nlm.nih.gov/31361950
Autor:
Manohar Pilli, Yordan Kostov, Leah Tolosa, Govind Rao, Xudong Ge, Abhay Andar, Chandrasekhar Gurramkonda, David Burgenson
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-7 (2018)
Scientific Reports
Scientific Reports
Several groups have recently reported on the utility of cell-free expression systems to make therapeutic proteins, most of them employing CHO or E. coli cell-free extracts. Here, we propose an alternative that uses human blood derived leukocyte cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50771a82610820a207ac3170e24b6fe1
Autor:
Erick Gutierrez, David Burgenson, Sevda Deldari, Govind Rao, Chandrasekhar Gurramkonda, Abhay Andar, Douglas D. Frey, Mustafa Al-Adhami, Leah Tolosa, Yordan Kostov
Publikováno v:
Biotechnology and bioengineering. 116(4)
Biopharmaceutical separations require tremendous amounts of optimization to achieve acceptable product purity. Typically, large volumes of reagents and biological materials are needed for testing different parameters, thus adding to the expense of bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::749716d1738f654a070834b2a9abc4ad
https://pubmed.ncbi.nlm.nih.gov/30450616
https://pubmed.ncbi.nlm.nih.gov/30450616
Autor:
Joshua A. Wilhide, Douglas D. Frey, Adil Zuber, Yordan Kostov, Merideth A. Cooper, Mustafa Al-Adhami, Manohar Pilli, David W. Wood, Antonio Moreira, Chandrasekhar Gurramkonda, Sergei I. Snovida, Sheniqua Brown, Xudong Ge, Yang Liu, David Burgenson, KarunaSri Mupparapu, Abhay Andar, Michael Tolosa, Penny Jensen, Brandon Wagner, Chariz Peñalber-Johnstone, Sudha Veeraraghavan, Krishna Vattem, Benjamin Punshon-Smith, Kanika Taurani, Hui Guo, Sevda Deldari, Aniruddha Rao, Rajani Adiga, Kevin Tran, Leah Tolosa, William R. LaCourse, Dagmawi Tilahun, Priyanka Rauniyar, Govind Rao, Shayan Borhani
Publikováno v:
Nature biomedical engineering. 2(9)
Manufacturing technologies for biologics rely on large, centralized, good-manufacturing-practice (GMP) production facilities and on a cumbersome product-distribution network. Here, we report the development of an automated and portable medicines-on-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a95fbf6f9c979339db02390d8737bd4
https://pubmed.ncbi.nlm.nih.gov/31015674
https://pubmed.ncbi.nlm.nih.gov/31015674