Zobrazeno 1 - 10 of 23 pro vyhledávání: '"David Boocock"'
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Akademický článek
Xylo-oligosaccharide-based prebiotics upregulate the proteins of the Sus-like system in caecal Bacteroidetes of the chicken: evidence of stimbiotic mechanism
Autor: Saba E. Amir, M. Naeem, David Boocock, Clare Coveney, H.M. O'Neill, M.R. Bedford, E.J. Burton
Publikováno v: Poultry Science, Vol 102, Iss 12, Pp 103113- (2023)
ABSTRACT: The present study was conducted to investigate the stimbiotic mechanism of xylo-oligosaccharide (XOS) in degrading the complex polysaccharides by the caecal bacteria of the chicken, by applying a proteomic approach. A total of 800 as-hatche
Externí odkaz: https://doaj.org/article/c96151b2c4374801b48ddf11cc564af8
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2
Akademický článek
Homocitrullination of lysine residues mediated by myeloid-derived suppressor cells in the tumor environment is a target for cancer immunotherapy
Autor: Wei Xue, Victoria A Brentville, Suha Atabani, Peter Symonds, Katherine W Cook, Poonam Vaghela, Lindy G Durrant, David Boocock, Clare Coveney, Amanda K Miles, Sabaria Shah, Daisy Weston
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 9, Iss 7 (2021)
Background Homocitrullination is the post-translational modification of lysine that is recognized by T cells.Methods This study identified homocitrullinated peptides from aldolase, enolase, cytokeratin and binding immunoglobulin protein and used huma
Externí odkaz: https://doaj.org/article/8304c7bef9614211b835d19438adf38c
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3
PARP1 mediated PARylation contributes to myogenic progression and glucocorticoid transcriptional response
Autor: Arnold Tan, Awais Younis, Jade Creighton, Alexander Evans, Clare Coveney, David Boocock, Craig Sale, Gareth Lavery, Amanda Coutts, Craig Doig
Poly-(ADP-ribose)polymerase 1 (PARP1) enzymatically generates and applies the post-translational modification, as mono (MAR) or poly (PAR) ADP-Ribose (ADPR) chains. PARP1 roles in genome maintenance are well described, but recent work highlight roles
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::613df06c3c60ee035bc4f205b9680257
https://doi.org/10.21203/rs.3.rs-2227540/v1
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6
OR07-5 PARP1 Contributes to the Glucocorticoid Receptor Transcriptional Response And Influences the Skeletal Muscle Phenotype
Autor: David Boocock, Clare Coveney, Jade Creighton, Craig Doig, Craig Sale, Nick Weir, Awais Younis, Arnold Tan
Publikováno v: Journal of the Endocrine Society. 6:A724-A724
Background NAD+-dependent PARP1 (Poly-(ADP-ribosyl)polymerase 1) generates the post-translational modification ADP-Ribosylation (ADPR). Given PARP1-ADPR determines cellular NAD+ availability, which in turn impacts a range of hormonally governed actio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::816228444f958f3f540e79633cab8eb5
https://doi.org/10.1210/jendso/bvac150.1492
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8
Effect of cyanidin-3-glucoside and an anthocyanin mixture from bilberry on adenoma development in the ApcMin mouse model of intestinal carcinogenesis--relationship with tissue anthocyanin levels
Autor: Darren, Cooke, Michael, Schwarz, David, Boocock, Peter, Winterhalter, William P, Steward, Andreas J, Gescher, Timothy H, Marczylo
Publikováno v: International journal of cancer. 119(9)
Anthocyanins are dietary flavonoids, which can prevent carcinogen-induced colorectal cancer in rats. Here, the hypotheses were tested that Mirtoselect, an anthocyanin mixture from bilberry, or isolated cyanidin-3-glucoside (C3G), the most abundant an
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::09f2196f007c1299d4371d1115a106b7
https://pubmed.ncbi.nlm.nih.gov/16823841
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