Zobrazeno 1 - 8
of 8
pro vyhledávání: '"David Bohr"'
Autor:
Patrick H. Lizotte, Paul Paik, Liviu Niculescu, Seng-Lai H. Tan, David Bohr, Elham Gharakhani, Ralf Reiners, Rachel Salazar, Avanish Varshney, Shiv Ram Krishn, Pradip Nair, Cloud Paweletz
Publikováno v:
Cancer Research. 83:6677-6677
Background: BCA101 is a bispecific antibody targeting EGFR and TGF-β. TGF-β pathway activation is a hallmark of human immune-excluded tumors, and TGF-β expression is associated with resistance to anti-PD-1 blockade. Neutralization of TGF-β remove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62c24a265630ececd3d4825fc2b2e0be
https://doi.org/10.1158/1538-7445.am2023-6677
https://doi.org/10.1158/1538-7445.am2023-6677
Autor:
Philippe L. Bedard, Alberto Hernando-Calvo, Richard D. Carvajal, Van K. Morris, Paul K. Paik, Dan Paul Zandberg, John M. Kaczmar, Liviu Niculescu, David Bohr, Ralf Reiners, Elham Gharakhani, Rachel Salazar, Sanela Bilic, Glenn J. Hanna
Publikováno v:
Journal of Clinical Oncology. 40:2513-2513
2513 Background: BCA101 is a first-in-class bifunctional fusion protein consisting of an anti-EGFR monoclonal antibody (mAb) and TGFβ receptor 2 extracellular domain (TGFβRII-ECD). Herein, we report the safety, pharmacokinetic (PK), pharmacodynamic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74e72edbf48c418e46a14ab748e38f81
https://doi.org/10.1200/jco.2022.40.16_suppl.2513
https://doi.org/10.1200/jco.2022.40.16_suppl.2513
Autor:
Glenn J. Hanna, Jennifer J. Wheler, Filip Janku, Paul K. Paik, Philippe L. Bedard, David Bohr, Ralf Reiners, Alberto Hernando-Calvo, Richard D. Carvajal, Siqing Fu, Maura L. Gillison, Seng-Lai Tan, Sanela Bilic
Publikováno v:
Journal of Clinical Oncology. 39:3074-3074
3074 Background: Therapeutic targeting of EGFR has demonstrated efficacy in common advanced malignancies such as colorectal cancer (CRC), squamous cell of the head and neck (SCCHN), and non-small cell lung cancer (NSCLC). TGFβ has pro-tumorigenic ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6bf0269708baa3cfdd645adbcc015e31
https://doi.org/10.1200/jco.2021.39.15_suppl.3074
https://doi.org/10.1200/jco.2021.39.15_suppl.3074
Autor:
David Bohr
In a robust and engaging manner, David Bohr offers us a thorough review and timely reanalysis of the Catholic diocesan priesthood. Biblical, historical, and sacramental voices dialogue with the relevant documents of the Second Vatican Council, other
Autor:
Joanne F. Chou, Daniel Paucar, Ruth Ann Roman, Gary K. Schwartz, Katherine S. Panageas, Jedd D. Wolchok, Brian P. Marr, Mark J. Bluth, Mary Montefusco, Richard D. Carvajal, Mark A. Dickson, Anne Fusco, Sandra P. D'Angelo, David Bohr, Paul B. Chapman, David H. Abramson, L. Austin Doyle, Grazia Ambrosini
Publikováno v:
Journal of Clinical Oncology. 30:8598-8598
8598 Background: Functionally activating mutations (mut) in Gnaq or Gna11, genes that encode for widely expressed G-protein alpha subunits, are early oncogenic events in uveal melanoma (UM) development and result in activation of the MAPK pathway. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17dff360235d0fb1d4f67f8fe3cdbb1a
https://doi.org/10.1200/jco.2012.30.15_suppl.8598
https://doi.org/10.1200/jco.2012.30.15_suppl.8598
Autor:
Christoph Mark, Thomas J Grundy, Pamela L Strissel, David Böhringer, Nadine Grummel, Richard Gerum, Julian Steinwachs, Carolin C Hack, Matthias W Beckmann, Markus Eckstein, Reiner Strick, Geraldine M O'Neill, Ben Fabry
Publikováno v:
eLife, Vol 9 (2020)
Externí odkaz:
https://doaj.org/article/0ec86de194b7479ebb7bb33449e96200
Autor:
Christoph Mark, Thomas J Grundy, Pamela L Strissel, David Böhringer, Nadine Grummel, Richard Gerum, Julian Steinwachs, Carolin C Hack, Matthias W Beckmann, Markus Eckstein, Reiner Strick, Geraldine M O'Neill, Ben Fabry
Publikováno v:
eLife, Vol 9 (2020)
We describe a method for quantifying the contractile forces that tumor spheroids collectively exert on highly nonlinear three-dimensional collagen networks. While three-dimensional traction force microscopy for single cells in a nonlinear matrix is c
Externí odkaz:
https://doaj.org/article/445809e39596411894c241e66afcfafe
Autor:
Gregor Peters, Olaf Wendler, David Böhringer, Antoniu-Oreste Gostian, Sarina K. Müller, Herbert Canziani, Nicolas Hesse, Marion Semmler, David A. Berry, Stefan Kniesburges, Wolfgang Peukert, Michael Döllinger
Publikováno v:
Applied Sciences, Vol 11, Iss 7, p 3011 (2021)
Mucus consistency affects voice physiology and is connected to voice disorders. Nevertheless, the rheological characteristics of human laryngeal mucus from the vocal folds remain unknown. Knowledge about mucus viscoelasticity enables fabrication of a
Externí odkaz:
https://doaj.org/article/442b1819402345128287a444a6366367