Zobrazeno 1 - 6
of 6
pro vyhledávání: '"David Bernson"'
Publikováno v:
Biomolecules, Vol 10, Iss 6, p 924 (2020)
Plaque deposits composed of amyloid-β (Aβ) fibrils are pathological hallmarks of Alzheimer’s disease (AD). Although copper ion dyshomeostasis is apparent in AD brains and copper ions are found co-deposited with Aβ peptides in patients’ plaques
Externí odkaz:
https://doaj.org/article/335b8cd9a24e4aa592546e1f04ebddb2
Autor:
Alexandra Paul, David Bernson, Xiaolu Zhang, Emelie Wesén, Ranjeet Kumar, Elin K. Esbjörner, Audrey Gallud, Pernilla Wittung-Stafshede
Publikováno v:
ACS Chemical Neuroscience. 11:233-241
Aggregation and intracellular deposition of the protein α-synuclein is an underlying characteristic of Parkinson's disease. α-Synuclein assemblies also undergo cell-cell spreading, facilitating propagation of their cellular pathology. Understanding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dafb90cb5ab2fd9e0939a0d2ffa13cd
https://doi.org/10.1021/acschemneuro.9b00562
https://doi.org/10.1021/acschemneuro.9b00562
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Amyloid fibrils are generally related to neurodegenerative diseases, but they can also be part of normal protein function. Amyloid formation involves numerous steps and intermediate species. In this study, we investigated a fish protein,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad03b34b8e1179df7ffb0a3978dd4c51
https://pubmed.ncbi.nlm.nih.gov/33093204
https://pubmed.ncbi.nlm.nih.gov/33093204
Graphene oxide sheets and quantum dots inhibit α-synuclein amyloid formation by different mechanisms
Publikováno v:
Nanoscale. 12(37)
Aggregation and amyloid formation of the 140-residue presynaptic and intrinsically disordered protein α-synuclein (α-syn) is a pathological hallmark of Parkinson's disease (PD). Understanding how α-syn forms amyloid fibrils, and investigations of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b9847634390c0519f109a79c7edf0d9
https://pubmed.ncbi.nlm.nih.gov/32959853
https://pubmed.ncbi.nlm.nih.gov/32959853
Autor:
István T. Horváth, David Bernson, Elin K. Esbjörner, Nima Sasanian, Pernilla Wittung-Stafshede
Publikováno v:
Biomolecules, Vol 10, Iss 924, p 924 (2020)
Biomolecules
Volume 10
Issue 6
Biomolecules
Volume 10
Issue 6
Plaque deposits composed of amyloid-&beta
(A&beta
) fibrils are pathological hallmarks of Alzheimer&rsquo
s disease (AD). Although copper ion dyshomeostasis is apparent in AD brains and copper ions are found co-deposited with A&beta
(A&beta
) fibrils are pathological hallmarks of Alzheimer&rsquo
s disease (AD). Although copper ion dyshomeostasis is apparent in AD brains and copper ions are found co-deposited with A&beta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc0f2673fb2208f2beede566ce9edb75
https://www.mdpi.com/2218-273X/10/6/924
https://www.mdpi.com/2218-273X/10/6/924
Autor:
David Bernson, Fredrik Limé, Magnus Palmlöf, Almedina Mecinovic, Per Jageland, Elin K. Esbjörner, Tuhin Abed
Publikováno v:
European Biophysics Journal
Protein aggregation and amyloid formation are associated with multiple human diseases, but are also a problem in protein production. Understanding how aggregation can be modulated is therefore of importance in both medical and industrial contexts. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47984d46be9fce2775ce4065aa8f92e4
https://pubmed.ncbi.nlm.nih.gov/31901953
https://pubmed.ncbi.nlm.nih.gov/31901953