Zobrazeno 1 - 10
of 14
pro vyhledávání: '"David Benziger"'
Publikováno v:
Pediatric Infectious Disease Journal. 33:936-939
Daptomycin is approved for treatment of complicated skin/skin structure infections and Staphylococcus aureus bloodstream infections (bacteremia) in adults. This study was undertaken to determine the pharmacokinetics of daptomycin in pediatric patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3249bebf6367e454e0e69a9bc2163557
https://doi.org/10.1097/inf.0000000000000318
https://doi.org/10.1097/inf.0000000000000318
Autor:
David Benziger, John S. Bradley, Julie Donovan, Richard F. Jacobs, Gurudatt Chandorkar, Ronda L. Akins, Susan M. Abdel-Rahman
Publikováno v:
Pediatric Infectious Disease Journal. 30:712-714
A pharmacokinetic analysis was performed for single intravenous doses of daptomycin 8 or 10 mg/kg in subjects aged 2 to 6 years. Proportional increases in maximum plasma concentration (68.4 μg/mL, 79.2 μg/mL) and area under the curve (429.1 μg ·
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::642942a10630e1b223f970c9cd42be9a
https://doi.org/10.1097/inf.0b013e31820fc8e1
https://doi.org/10.1097/inf.0b013e31820fc8e1
Publikováno v:
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists. 71(13)
Purpose A case series in which a novel dosing strategy for managing mild, asymptomatic creatine kinase (CK) increases associated with daptomycin therapy is presented. Summary Eight patients received a mean daptomycin dosage of 7.75 mg/kg/day for a me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b55d675c7cc7e2a79eba41935c8c297a
https://pubmed.ncbi.nlm.nih.gov/24939500
https://pubmed.ncbi.nlm.nih.gov/24939500
Publikováno v:
The Journal of antimicrobial chemotherapy. 69(1)
Objectives:TosupportdaptomycindosingrecommendationsinpatientswithStaphylococcusaureusbacteraemia (SAB) and severe renal impairment using simulations from a population pharmacokinetic model for daptomycin. Methods: A population pharmacokinetic model w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f3d99a69dbec02ef16c536b0f8ff8b8
https://pubmed.ncbi.nlm.nih.gov/24030545
https://pubmed.ncbi.nlm.nih.gov/24030545
The pharmacokinetics and safety of ceftolozane, a novel cephalosporin, and tazobactam, a β-lactamase inhibitor, alone and in combination as a 2:1 ratio in single doses of up to 2,000 and 1,000 mg of ceftolozane and tazobactam, respectively, and mult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2af1c078864c54f8442a50a745bb06e1
https://europepmc.org/articles/PMC3370713/
https://europepmc.org/articles/PMC3370713/
Autor:
Erica Fischer Hong, Susan M. Abdel-Rahman, David Benziger, Hasan S. Jafri, Richard F. Jacobs, Gregory L. Kearns
Publikováno v:
The Pediatric infectious disease journal. 27(4)
New antimicrobials such as daptomycin fill a void in the growing need for antibiotics effective against resistant Gram-positive pathogens. Although the pharmacokinetics of daptomycin have been well characterized in adults, no studies have evaluated t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ea1a3e1c1d8b0b3587698aaaee695f6
https://pubmed.ncbi.nlm.nih.gov/18316988
https://pubmed.ncbi.nlm.nih.gov/18316988
Publikováno v:
Antimicrobial agents and chemotherapy. 50(10)
Daptomycin, a novel lipopeptide, is bactericidal against a broad range of gram-positive strains, including methicillin- (MRSA) and vancomycin-resistant Staphylococcus aureus . Daptomycin is approved at 4 mg/kg of body weight given intravenously once
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4226e137d2fd5dcbf7bd51507cc4d9cc
https://pubmed.ncbi.nlm.nih.gov/17005801
https://pubmed.ncbi.nlm.nih.gov/17005801
Autor:
Nicholas J. Patronas, Timothy O'Toole, Peter C. Adamson, Mahendra C. Patel, Alberta A. Aikin, Katherine E. Warren, David Benziger, Madeleine Libucha, Brigitte C. Widemann, Rachel B. Neuwirth, Kathleen Ford, Roger J. Packer, Frank M. Balis
Publikováno v:
Cancer chemotherapy and pharmacology. 48(4)
Purpose: To determine the maximum tolerated dose (MTD), the incidence and severity of toxicities, and the pharmacokinetics of lobradimil administered intravenously over 10 min in combination with carboplatin in children with refractory brain tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a101b9185a396b30f21d6da0dcc084b5
https://pubmed.ncbi.nlm.nih.gov/11710627
https://pubmed.ncbi.nlm.nih.gov/11710627
Publikováno v:
Anesthesiology. 89(4)
Background Previous work from the authors' group characterized a prolonged percutaneous blockade of the sciatic nerve in rats using bupivacaine-dexamethasone microspheres. The goals of the current study are to examine the (1) efficacy of bupivacaine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3a3d35a69c0dde617695b7f2072adbc
https://pubmed.ncbi.nlm.nih.gov/9778015
https://pubmed.ncbi.nlm.nih.gov/9778015
Publikováno v:
Comparative Biochemistry and Physiology Part C: Comparative Pharmacology. 51:111-115
1. 1. The addition of either epinephrine or glucagon to incubating liver pieces prevents the decay of glycogen phosphorylase activity seen in controls. 2. 2. The degree to which these hormones stimulate phosphorylase activity after 30 min of incubati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fd7307185ca08684fe810aca83480af
https://doi.org/10.1016/0306-4492(75)90047-7
https://doi.org/10.1016/0306-4492(75)90047-7