Zobrazeno 1 - 10
of 43
pro vyhledávání: '"David Bending"'
Autor:
Juan F Quintana, Matthew C Sinton, Praveena Chandrasegaran, Lalit Kumar Dubey, John Ogunsola, Moumen Al Samman, Michael Haley, Gail McConnell, Nono-Raymond Kuispond Swar, Dieudonné Mumba Ngoyi, David Bending, Luis de Lecea, Annette MacLeod, Neil A Mabbott
Publikováno v:
PLoS Biology, Vol 21, Iss 11, p e3002389 (2023)
The meningeal space is a critical brain structure providing immunosurveillance for the central nervous system (CNS), but the impact of infections on the meningeal immune landscape is far from being fully understood. The extracellular protozoan parasi
Externí odkaz:
https://doaj.org/article/253eccf81f604fb09b7c9c3cff71ce65
Autor:
Lozan Sheriff, David Bending
Publikováno v:
STAR Protocols, Vol 3, Iss 1, Pp 101161- (2022)
Summary: This protocol uses the Tg4 Nr4a3-Tocky mouse model to recalibrate T cell activation thresholds and reveals the role that immune checkpoints play in controlling T cell activation. The example approach here uses flow cytometry to characterize
Externí odkaz:
https://doaj.org/article/11f48dc8928b48fa913f166de2c859ad
Publikováno v:
STAR Protocols, Vol 2, Iss 1, Pp 100284- (2021)
Summary: This protocol uses Nr4a1-GFP Nr4a3-Tocky mice to study T cell receptor (TCR) signaling using flow cytometry. It identifies the optimal mouse transgenic status and fluorochromes compatible with the dual reporter. This protocol has application
Externí odkaz:
https://doaj.org/article/522f6c739abd4cc2b2353f7b18c64a89
Autor:
Emma Jennings, Thomas A.E. Elliot, Natasha Thawait, Shivani Kanabar, Juan Carlos Yam-Puc, Masahiro Ono, Kai-Michael Toellner, David C. Wraith, Graham Anderson, David Bending
Publikováno v:
Cell Reports, Vol 33, Iss 5, Pp 108328- (2020)
Summary: Nr4a receptors are activated by T cell receptor (TCR) signaling and play key roles in T cell differentiation. Which TCR signaling pathways regulate Nr4a receptors and their sensitivities to TCR signal strength and duration remains unclear. U
Externí odkaz:
https://doaj.org/article/2a8552a3db8b42ca9b7d30801fa9df36
Autor:
Alastair Copland, David Bending
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Since the identification of the regulatory T-cell (Treg)-associated transcription factor Foxp3, there have been intensive research efforts to understand its biology and roles in maintaining immune homeostasis. It is well established that thymic selec
Externí odkaz:
https://doaj.org/article/c60b122c07104d538090e3d86730ac36
Autor:
Alastair Copland, Gillian M. Mackie, Lisa Scarfe, David A.J. Lecky, Nancy Gudgeon, Riahne McQuade, Masahiro Ono, Manja Barthel, Wolf-Dietrich Hardt, Hiroshi Ohno, Sarah Dimeloe, David Bending, Kendle M. Maslowski
SummaryBacterial cancer therapy (BCT) is a promising therapeutic for solid tumours.Salmonella entericaTyphimurium (STm) is well-studied amongst bacterial vectors due to advantages in genetic modification and metabolic adaptation. A longstanding parad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cdef840a53f9760c119927240987e121
https://doi.org/10.1101/2023.01.12.523780
https://doi.org/10.1101/2023.01.12.523780
Autor:
Carly E. Whyte, Kailash Singh, Oliver T. Burton, Meryem Aloulou, Lubna Kouser, Rafael Valente Veiga, Amy Dashwood, Hanneke Okkenhaug, Samira Benadda, Alena Moudra, Orian Bricard, Stephanie Lienart, Pascal Bielefeld, Carlos P. Roca, Francisco José Naranjo-Galindo, Félix Lombard-Vadnais, Steffie Junius, David Bending, Masahiro Ono, Tino Hochepied, Timotheus Y.F. Halim, Susan Schlenner, Sylvie Lesage, James Dooley, Adrian Liston
Publikováno v:
Journal of Experimental Medicine. 219
Autor:
Carly E. Whyte, Kailash Singh, Oliver T. Burton, Meryem Aloulou, Lubna Kouser, Rafael Valente Veiga, Amy Dashwood, Hanneke Okkenhaug, Samira Benadda, Alena Moudra, Orian Bricard, Stephanie Lienart, Pascal Bielefeld, Carlos P. Roca, Francisco José Naranjo-Galindo, Félix Lombard-Vadnais, Steffie Junius, David Bending, Masahiro Ono, Tino Hochepied, Timotheus Y.F. Halim, Susan Schlenner, Sylvie Lesage, James Dooley, Adrian Liston
Publikováno v:
JOURNAL OF EXPERIMENTAL MEDICINE
Funder: Fondation pour l'Aide à la Recherche sur la Sclérose en Plaques
Funder: Alzheimer's Association
Funder: European Research Council
Funder: Fondation pour l’Aide à la Recherche sur la Sclérose en Plaques
Funder: Vetens
Funder: Alzheimer's Association
Funder: European Research Council
Funder: Fondation pour l’Aide à la Recherche sur la Sclérose en Plaques
Funder: Vetens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff38c09def949c44dafdb80179d4c709
https://doi.org/10.1084/jem.20212391
https://doi.org/10.1084/jem.20212391
Autor:
David Bending, Julie Zikherman
Publikováno v:
Current Opinion in Immunology. 81:102285
Publikováno v:
Cell Reports Medicine. 4:100989