Zobrazeno 1 - 10
of 51
pro vyhledávání: '"David Balgoma"'
Autor:
Maria Kopsida, Ada Lerma Clavero, Jaafar Khaled, David Balgoma, Clara Luna-Marco, Azazul Chowdhury, Sofi Sennefelt Nyman, Fredrik Rorsman, Charlotte Ebeling Barbier, Peter Bergsten, Hans Lennernäs, Mikael Hedeland, Femke Heindryckx
Publikováno v:
Molecular Metabolism, Vol 79, Iss , Pp 101846- (2024)
Hepatocellular carcinoma (HCC) is characterized by a low and variable response to chemotherapeutic treatments. One contributing factor to the overall pharmacodynamics is the activation of endoplasmic reticulum (ER) stress pathways. This is a cellular
Externí odkaz:
https://doaj.org/article/a28070bb6a72401c97ac140010fab73d
Autor:
Vasiliki Koutsouveli, David Balgoma, Antonio Checa, Mikael Hedeland, Ana Riesgo, Paco Cárdenas
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-20 (2022)
Abstract Sponges contain an astounding diversity of lipids that serve in several biological functions, including yolk formation in their oocytes and embryos. The study of lipid metabolism during reproduction can provide information on food-web dynami
Externí odkaz:
https://doaj.org/article/bf4e388a55484d0bb627cd45bce2de58
Autor:
David Balgoma, Fredrik Kullenberg, Karsten Peters, David Dahlgren, Femke Heindryckx, Hans Lennernäs, Mikael Hedeland
Publikováno v:
Metabolites, Vol 12, Iss 9, p 866 (2022)
Ad libitum feeding of experimental animals is preferred because of medical relevance together with technical and practical considerations. In addition, ethical committees may require ad libitum feeding. However, feeding affects the metabolism so ad l
Externí odkaz:
https://doaj.org/article/b796cac483c148ec8ada85f1173c28ac
Publikováno v:
Metabolites, Vol 12, Iss 5, p 452 (2022)
Correct assessment of the fatty acyl at the glycerol sn-2 position in triacylglycerol (TAG) analysis by liquid chromatography and mass spectrometry (LC-MS) is challenging. Ammonium hydroxide (NH4OH) is the preferred choice for the solvent additive fo
Externí odkaz:
https://doaj.org/article/ec3e06f5101545a99e9db2f3f77f33d2
Autor:
Kristian Pirttilä, David Balgoma, Johannes Rainer, Curt Pettersson, Mikael Hedeland, Carl Brunius
Publikováno v:
Metabolites, Vol 12, Iss 2, p 137 (2022)
LC–MS-based untargeted metabolomics is heavily dependent on algorithms for automated peak detection and data preprocessing due to the complexity and size of the raw data generated. These algorithms are generally designed to be as inclusive as possi
Externí odkaz:
https://doaj.org/article/f2d23150f812470b8d52e54504d46a25
Autor:
Fredrik Kullenberg, Oliver Degerstedt, Carlemi Calitz, Nataša Pavlović, David Balgoma, Johan Gråsjö, Erik Sjögren, Mikael Hedeland, Femke Heindryckx, Hans Lennernäs
Publikováno v:
Cells, Vol 10, Iss 7, p 1717 (2021)
Cytostatic effects of doxorubicin in clinically applied doses are often inadequate and limited by systemic toxicity. The main objective of this in vitro study was to determine the anti-tumoral effect (IC50) and intracellular accumulation of free and
Externí odkaz:
https://doaj.org/article/0957576a8afc4411ac977d7f636e642b
Autor:
David Balgoma, Fredrik Kullenberg, Carlemi Calitz, Maria Kopsida, Femke Heindryckx, Hans Lennernäs, Mikael Hedeland
Publikováno v:
Cells, Vol 10, Iss 5, p 1163 (2021)
Metabolic and personalized interventions in cancer treatment require a better understanding of the relationship between the induction of cell death and metabolism. Consequently, we treated three primary liver cancer cell lines with two anthracyclins
Externí odkaz:
https://doaj.org/article/6a0ea0d915bc4537b4110c7deff952c5
Autor:
Jérémy Marchand, Yann Guitton, Estelle Martineau, Anne-Lise Royer, David Balgoma, Bruno Le Bizec, Patrick Giraudeau, Gaud Dervilly
Publikováno v:
Foods, Vol 10, Iss 6, p 1218 (2021)
From a general public health perspective, a strategy combining non-targeted and targeted lipidomics MS-based approaches is proposed to identify disrupted patterns in serum lipidome upon growth promoter treatment in pigs. Evaluating the relative contr
Externí odkaz:
https://doaj.org/article/0ff7992ed5b24838943451aea548864b
Publikováno v:
Metabolites, Vol 10, Iss 9, p 356 (2020)
The pathogenic mechanisms underlying the Biology and Biochemistry of viral infections are known to depend on the lipid metabolism of infected cells. From a lipidomics viewpoint, there are a variety of mechanisms involving virus infection that encompa
Externí odkaz:
https://doaj.org/article/1ff4c4be600d47e6b749e113cb0c10ab
Publikováno v:
Metabolites, Vol 10, Iss 8, p 332 (2020)
While immunotherapies for diverse types of cancer are effective in many cases, relapse is still a lingering problem. Like tumor cells, activated immune cells have an anabolic metabolic profile, relying on glycolysis and the increased uptake and synth
Externí odkaz:
https://doaj.org/article/9efbb62f9db64d99abbe34f87d579a5f