Zobrazeno 1 - 10
of 37
pro vyhledávání: '"David B. Lukatsky"'
Publikováno v:
iScience, Vol 2, Iss , Pp 141-147 (2018)
Summary: Primases are key enzymes involved in DNA replication. They act on single-stranded DNA and catalyze the synthesis of short RNA primers used by DNA polymerases. Here, we investigate the DNA binding and activity of the bacteriophage T7 primase
Externí odkaz:
https://doaj.org/article/a69b4104d3494e6cada3a66d4dcc8890
Autor:
Masahiko Imashimizu, Yuji Tokunaga, Ariel Afek, Hiroki Takahashi, Nobuo Shimamoto, David B. Lukatsky
Publikováno v:
Biomolecules, Vol 10, Iss 9, p 1299 (2020)
In the process of transcription initiation by RNA polymerase, promoter DNA sequences affect multiple reaction pathways determining the productivity of transcription. However, the question of how the molecular mechanism of transcription initiation dep
Externí odkaz:
https://doaj.org/article/3c0b6fc2bb6046b39b93029889027212
Autor:
Shiran Lacham-Hartman, Yulia Shmidov, Evette S Radisky, Ronit Bitton, David B Lukatsky, Niv Papo
Publikováno v:
PLoS ONE, Vol 16, Iss 11, p e0249616 (2021)
Although myriad protein-protein interactions in nature use polyvalent binding, in which multiple ligands on one entity bind to multiple receptors on another, to date an affinity advantage of polyvalent binding has been demonstrated experimentally onl
Externí odkaz:
https://doaj.org/article/85fd5f0416b848ddb4bd776b3283d717
Autor:
Meir Mellul, Shlomtzion Lahav, Masahiko Imashimizu, Yuji Tokunaga, David B. Lukatsky, Oren Ram
Publikováno v:
Biophysical journal. 121(16)
Transcription factor (TF) binding to genomic DNA elements constitutes one of the key mechanisms that regulates gene expression program in cells. Both consensus and nonconsensus DNA sequence elements influence the recognition specificity of TFs. Based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cee5fb2152ae5de8776e4b398ae10ef
https://pubmed.ncbi.nlm.nih.gov/35810331
https://pubmed.ncbi.nlm.nih.gov/35810331
Autor:
Nobuo Shimamoto, David B. Lukatsky, Ariel Afek, Masahiko Imashimizu, Yuji Tokunaga, Hiroki Takahashi
Publikováno v:
Biomolecules, Vol 10, Iss 1299, p 1299 (2020)
Biomolecules
Volume 10
Issue 9
Biomolecules
Volume 10
Issue 9
In the process of transcription initiation by RNA polymerase, promoter DNA sequences affect multiple reaction pathways determining the productivity of transcription. However, the question of how the molecular mechanism of transcription initiation dep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac9d0b9642fb8d59df046e22155e38a3
https://www.mdpi.com/2218-273X/10/9/1299
https://www.mdpi.com/2218-273X/10/9/1299
Autor:
David B. Lukatsky
Publikováno v:
Biophys J
Protein diffusion in lower-dimensional spaces is used for various cellular functions. For example, sliding on DNA is essential for proteins searching for their target sites, and protein diffusion on microtubules is important for proper cell division
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57202603fbe721323cc767ff4207a389
https://europepmc.org/articles/PMC7300304/
https://europepmc.org/articles/PMC7300304/
Autor:
Niv Papo, Evette S. Radisky, Yulia Shmidov, Shiran Lacham-Hartman, Ronit Bitton, David B. Lukatsky
Publikováno v:
PLoS ONE, Vol 16, Iss 11, p e0249616 (2021)
PLoS ONE
PLoS ONE
Although myriad protein–protein interactions in nature use polyvalent binding, in which multiple ligands on one entity bind to multiple receptors on another, to date an affinity advantage of polyvalent binding has been demonstrated experimentally o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b02409e4eef329f522e83ec9f7cbf5a7
https://doi.org/10.1371/journal.pone.0249616
https://doi.org/10.1371/journal.pone.0249616
Autor:
David B. Lukatsky, Masahiko Imashimizu
Publikováno v:
Transcription
Transcription of DNA by RNA polymerase (RNAP) takes place in a cell environment dominated by thermal fluctuations. How are transcription reactions including initiation, elongation, and termination on genomic DNA so well-controlled during such fluctua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52a5f9210f5bab0006f8ed9fd9975bc5
https://doi.org/10.1080/21541264.2017.1393492
https://doi.org/10.1080/21541264.2017.1393492
Publikováno v:
Journal of Visualized Experiments.
DNA primase synthesizes short RNA primers that initiate DNA synthesis of Okazaki fragments on the lagging strand by DNA polymerase during DNA replication. The binding of prokaryotic DnaG-like primases to DNA occurs at a specific trinucleotide recogni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::909db1ad1a1ea0d5cbe26bec12853925
https://doi.org/10.3791/59737
https://doi.org/10.3791/59737
Autor:
Goldshtein M, David B. Lukatsky
We analyze design principles of transcription factor (TF) recognition by genomic DNA in differentiating human embryonic stem cells for 36 TFs and five histone modifications in four developmental layers, using the data recently measured by Tsankov et
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4583f834506ae2b7ef23117925c769ce