Zobrazeno 1 - 10
of 18
pro vyhledávání: '"David B. Casey"'
Publikováno v:
Cardiovascular Revascularization Medicine. 17:102-105
Background The use of simulator-based teaching in cardiology has unfortunately lagged behind other procedural specialties. This study investigates the utility of a simulator-based training program for fellows in cardiovascular disease with no prior e
Publikováno v:
Clinical Case Reports
Key Clinical Message This case demonstrates two important points about Brugada syndrome unmasking: electrocardiograph abnormality severity may correspond to lithium levels and unmasking may occur in the therapeutic range of lithium. Also, the correla
Autor:
Subramanyam N. Murthy, Philip J. Kadowitz, Satvika Uppu, Adeleke R. Badejo, Edward A. Pankey, Bobby D. Nossaman, David B. Casey
Publikováno v:
Nitric Oxide. 26:223-228
Responses to glyceryl trinitrate/nitroglycerin (GTN), S-nitrosoglutathione (GSNO), and sodium nitrite were compared in the intact chest rat. The iv injections of GTN, sodium nitrite, and GSNO produced dose-dependent decreases in pulmonary and systemi
Autor:
Adeleke M. Badejo, Bobby D. Nossaman, Edward A. Pankey, Manish Bhartiya, Philip J. Kadowitz, David B. Casey, Franklin R. Bueno, Subramanyam N. Murthy, Rao M. Uppu
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 90:485-500
Peroxynitrite (PN) worsens pathological conditions associated with oxidative stress. However, beneficial effects have also been reported. PN has been shown to demonstrate vasodilator as well as vasoconstrictor properties that are dependent upon the e
Autor:
Albert L. Hyman, David B. Casey, Jasdeep S. Dhaliwal, Philip J. Kadowitz, Edward A. Pankey, Chris M Hodnette, Subramanyam N. Murthy, Bobby D. Nossaman, Adeleke M. Badejo
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 299:H819-H826
It has been reported that mitochondrial aldehyde dehydrogenase (ALDH2) catalyzes the formation of glyceryl dinitrate and inorganic nitrite from glyceryl trinitrate (GTN), leading to an increase in cGMP and vasodilation in the coronary and systemic va
Autor:
Subramanyam N. Murthy, Philip J. Kadowitz, Adeleke M. Badejo, James L Sikora, Alex Fokin, Jasdeep S. Dhaliwal, Bobby D. Nossaman, Neel H Golwala, Albert L. Hyman, David B. Casey, Anthony J. Greco
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 299:H184-H192
Responses to the Rho kinase inhibitor Y-27632 were investigated in the anesthetized rat. Under baseline conditions intravenous injections of Y-27632 decreased pulmonary and systemic arterial pressures and increased cardiac output. The decreases in pu
Autor:
Jennifer McGee, Vivian Fonseca, David B. Casey, Subramanyam N. Murthy, Rose-Claire St. Hilaire, Adeleke M. Badejo, Dennis B. McNamara, Philip J. Kadowitz
Publikováno v:
Diabetes and Vascular Disease Research. 7:138-144
We studied the effect of a synthetic GLP-1 receptor agonist, exenatide, a drug approved for the treatment of type 2 diabetes, on the recovery from vascular injury in Zucker (non-diabetic) fatty rats. Exenatide 5.0 µg/kg per day or saline was adminis
Autor:
Philip J. Kadowitz, Anthony J. Greco, David B. Casey, Adeleke M. Badejo, Jasdeep S. Dhaliwal, Thomas B. Gallen
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 295:L828-L836
The small GTP-binding protein Rho and its downstream effector, Rho-kinase, are important regulators of vasoconstrictor tone. Rho-kinase is upregulated in experimental models of pulmonary hypertension, and Rho-kinase inhibitors decrease pulmonary arte
Autor:
Edward A. Pankey, Subramanyam N. Murthy, George F. Lasker, Bobby D. Nossaman, Adeleke M. Badejo, Philip J. Kadowitz, David B. Casey, Russel A. Riehl
Publikováno v:
Nitric oxide : biology and chemistry. 27(1)
Pulmonary hypertension (PH) is a rare disorder that without treatment is progressive and often fatal within 3 years. The treatment of PH involves the use of a diverse group of drugs and lung transplantation. Although nitrite was once thought to be an
Autor:
David B. Casey, Adeleke M. Badejo, Dennis B. McNamara, Subramanyam N. Murthy, Cyrus Desouza, Jasdeep S. Dhaliwal, Jennifer McGee, Vivian Fonseca, Philip J. Kadowitz, Rose-Claire St. Hilaire, Neal W. Bost
Publikováno v:
Diabetes
OBJECTIVE Salsalate is a dimeric form of salicylic acid that has been shown to have anti-inflammatory activity and to reduce glucose levels, insulin resistance, and cytokine expression. However, the effect of salsalate on vascular injury has not been