Zobrazeno 1 - 10
of 227 239
pro vyhledávání: '"David B."'
Autor:
James K. Tsuruta, Patrick R. Sears, Meghan E. Rebuli, Andrew S. Weitz, Phillip G. Durham, Phillip W. Clapp, David B. Hill, Lawrence E. Ostrowski, Paul A. Dayton, Melissa C. Caughey
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Impaired mucociliary transport is a distinguishing sign of cystic fibrosis, but current methods of evaluation are invasive or expose young patients to ionizing radiation. Contrast-enhanced ultrasound imaging may provide a feasible alternativ
Externí odkaz:
https://doaj.org/article/60ce91fbc5ba4d92ba6957a17f0512a4
Autor:
Suryadipto Sarkar, Anna Möller, Anne Hartebrodt, Michael Erdmann, Christian Ostalecki, Andreas Baur, David B. Blumenthal
Publikováno v:
npj Systems Biology and Applications, Vol 10, Iss 1, Pp 1-9 (2024)
Abstract Cutaneous T-cell lymphomas (CTCLs) are non-Hodgkin lymphomas caused by malignant T cells which migrate to the skin and lead to rash-like lesions which can be difficult to distinguish from inflammatory skin conditions like atopic dermatitis (
Externí odkaz:
https://doaj.org/article/37bffc93f3fb44d4ad37d283e76e356c
Autor:
Katrina M. Jackson, Thomas J. Y. Kono, Jovany J. Betancourt, Yina Wang, Kisakye D. Kabbale, Minna Ding, Perry Kezh, Grace Ha, J. Marina Yoder, Sophie R. Fulton, Liliane Mukaremera, Peter Tiffin, Asiya Gusa, David B. Meya, R. Blake Billmyre, Chaoyang Xue, Kirsten Nielsen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Studies across various pathogens highlight the importance of pathogen genetic differences in disease manifestation. In the human fungal pathogen Cryptococcus neoformans, sequence type (ST) associates with patient outcome. We performed a meta
Externí odkaz:
https://doaj.org/article/17b9163ef9544640b277c3f479a1ed66
Autor:
Curtis P. Langlotz, MD, PhD, Johanna Kim, MPH, MBA, Nigam Shah, MBBS, PhD, Matthew P. Lungren, MD, MPH, David B. Larson, MD, MBA, Somalee Datta, PhD, Fei Fei Li, PhD, Ruth O’Hara, PhD, Thomas J. Montine, MD, PhD, Robert A. Harrington, MD, Garry E. Gold, MD, MS
Publikováno v:
Mayo Clinic Proceedings: Digital Health, Vol 2, Iss 4, Pp 677-686 (2024)
Artificial intelligence (AI) and machine learning (ML) are driving innovation in biosciences and are already affecting key elements of medical scholarship and clinical care. Many schools of medicine are capitalizing on the promise of these new techno
Externí odkaz:
https://doaj.org/article/eeb9f517049d40de890f847bbe5e3302
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 3506-3513 (2024)
Nucleotide-binding oligomerization domain, leucine rich repeat containing X1 (NLRX1) is a negative regulator of the nuclear factor kappa-light-chain-enhancer of activated B cells (NFκB) pathway, with a significant role in the context of inflammation
Externí odkaz:
https://doaj.org/article/93168126483d4c7e9002d63c0b41ef6a
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 3030-3039 (2024)
Current medical research has been demonstrating the roles of miRNAs in a variety of cellular mechanisms, lending credence to the association between miRNA dysregulation and multiple diseases. Understanding the mechanisms of miRNA is critical for deve
Externí odkaz:
https://doaj.org/article/3eca48283a8d4b4786dfaf8899d008ab
Autor:
Katherine Huang, Alex G. C. de Sá, Natalie Thomas, Robert D. Phair, Paul R. Gooley, David B. Ascher, Christopher W. Armstrong
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-14 (2024)
Abstract Background Diagnosing complex illnesses like Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is complicated due to the diverse symptomology and presence of comorbid conditions. ME/CFS patients often present with multiple health i
Externí odkaz:
https://doaj.org/article/5fab4358b9b24c208c476f3b0b588a37
Autor:
Vaseem M. Khatri, Mariella A. Mestres-Villanueva, Sreenija Yarlagadda, Ajay Doniparthi, David B. Smith, Justyn Y. Nakashima, John M. Bryant, Dekuang Zhao, Rituraj Upadhyay, Matthew N. Mills, Daniel E. Oliver, Hsiang-Hsuan Michael Yu, Joshua D. Palmer, Nicole O. Williams, Reshma L. Mahtani, Manmeet S. Ahluwalia, Hatem H. Soliman, Hyo S. Han, Aixa E. Soyano, Youngchul Kim, Rupesh Kotecha, Sasha J. Beyer, Kamran A. Ahmed
Publikováno v:
npj Breast Cancer, Vol 10, Iss 1, Pp 1-7 (2024)
Abstract Trastuzumab-deruxtecan (T-DXd) has demonstrated intracranial efficacy; however, safety and efficacy data remains limited with stereotactic radiosurgery (SRS). A multi-institutional review was performed with HER2+ or HER2-low metastatic breas
Externí odkaz:
https://doaj.org/article/00dfc0b23c294633bf4cfe25f01822be
Autor:
Surbhi Sidana, Andriyana K. Bankova, Hitomi Hosoya, Shaji K. Kumar, Tyson H. Holmes, John Tamaresis, Anne Le, Lori S. Muffly, Sofia Maysel-Auslender, Laura Johnston, Sally Arai, Robert Lowsky, Everett Meyer, Andrew Rezvani, Wen-Kai Weng, Matthew J. Frank, Parveen Shiraz, Holden T. Maecker, Ying Lu, David B. Miklos, Judith A. Shizuru
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract MGTA-145 or GROβT, a CXCR2 agonist, has shown promising activity for hematopoietic stem cell (HSC) mobilization with plerixafor in pre-clinical studies and healthy volunteers. Twenty-five patients with multiple myeloma enrolled in a phase 2
Externí odkaz:
https://doaj.org/article/c4ea76784f8e439895fbf960f62bde47
Autor:
Abdulwasiu B. Tiamiyu, Olutunde A. Adegbite, Olivia Freides, Seth Frndak, Samirah Sani Mohammed, Erica Broach, Kara Lombardi, Victor Anyebe, Roseline Akiga, Ndubuisi C. Okeke, Jegede E. Feyisayo, Oscar Ugwuezumba, Cassandra Akinde, Anthonia Osuji, Norah Agu, Tope Analogbei, Chinelo Ekweremadu, Danielle Bartolanzo, Petra Prins, Ying Fan, Doris Emekaili, Felicia Abah, Vincent Chiwetelu, Paul Dike, Esther Isaiah, Miriam Ayogu, Eunice Ogunkelu, Uzoamaka C. Agbaim, Adelekun Bukunmi, Yakubu Adamu, Tsedal Mebrahtu, Anastasia Zuppe, Matthew Johnston, Kayvon Modjarrad, Helina Meri, Zahra Parker, Edward Akinwale, Melanie D. McCauley, Glenna Schluck, David B. King, Leigh Anne Eller, Nathan Okeji, Ojor R. Ayemoba, Natalie D. Collins, Michael O. Iroezindu, Shilpa Hakre, EID023 Lassa study team
Publikováno v:
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-18 (2024)
Abstract Background Understanding the level of exposure to Lassa virus (LASV) in at-risk communities allows for the administration of effective preventive interventions to mitigate epidemics of Lassa fever. We assessed the seroprevalence of LASV anti
Externí odkaz:
https://doaj.org/article/d67feb47383449ba9f13dedd28fe3606