Zobrazeno 1 - 10
of 38
pro vyhledávání: '"David B Pilgrim"'
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0224206 (2019)
The structure and function of the sarcomere of striated muscle is well studied but the steps of sarcomere assembly and maintenance remain under-characterized. With the aid of chaperones and factors of the protein quality control system, muscle protei
Externí odkaz:
https://doaj.org/article/c6e429ada4964485b687d26996696d8d
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0148027 (2016)
Externí odkaz:
https://doaj.org/article/698dc154d0af4999a096cfa6586eefdd
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142528 (2015)
The vertebrate sarcomere is a complex and highly organized contractile structure whose assembly and function requires the coordination of hundreds of proteins. Proteins require proper folding and incorporation into the sarcomere by assembly factors,
Externí odkaz:
https://doaj.org/article/0ad267fc09e54f51ac43e0df9cf9583f
Autor:
Suey van Baarle, Ordan J. Lehmann, Paul W. Chrystal, Serhiy Havrylov, Curtis R. French, David B. Pilgrim, Andrew J. Waskiewicz, Ann-Marie Peturson, J. Gage Crump, Pengfei Xu, Francesca Jean
Normal body situs requires precise spatiotemporal expression of theNodal-Lefty-Pitx2cascade in the lateral plate mesoderm. The ultimate output of this patterning is establishment of the left-right axis, which provides vital cues for correct organ for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07a9c8684ed92c80921d6554c38c4284
https://doi.org/10.1101/2020.05.28.120915
https://doi.org/10.1101/2020.05.28.120915
Publikováno v:
The FASEB Journal. 33
In order to maintain homeostasis, defective proteins must be identified, removed, and replaced. In skeletal muscle, failures in this process can lead to a variety of incurable muscle diseases (myop...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04ac9e81e49610f737f8632c38466369
https://doi.org/10.1096/fasebj.2019.33.1_supplement.868.15
https://doi.org/10.1096/fasebj.2019.33.1_supplement.868.15
Autor:
Francesca Jean, David B. Pilgrim
Publikováno v:
Gene expression patterns : GEP. 33
UNC119 proteins are required for ciliary trafficking in a process called lipidated protein intraflagellar targeting (LIFT) or through vesicle transport. However, although unc119 has been studied in a variety of contexts, either organismal constraints
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1506763a7c76e15bf1d451f0eecfa707
https://pubmed.ncbi.nlm.nih.gov/31055152
https://pubmed.ncbi.nlm.nih.gov/31055152
Autor:
Francesca Jean, Curtis R. French, J. Gage Crump, Suey van Baarle, Pengfei Xu, Andrew J. Waskiewicz, Serhiy Havrylov, David B. Pilgrim, Ordan J. Lehmann, Paul W. Chrystal, Ann-Marie Peturson
Publikováno v:
Genes
Volume 12
Issue 2
Genes, Vol 12, Iss 170, p 170 (2021)
Volume 12
Issue 2
Genes, Vol 12, Iss 170, p 170 (2021)
Precise spatiotemporal expression of the Nodal-Lefty-Pitx2 cascade in the lateral plate mesoderm establishes the left&ndash
right axis, which provides vital cues for correct organ formation and function. Mutations of one cascade constituent PITX
right axis, which provides vital cues for correct organ formation and function. Mutations of one cascade constituent PITX
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad67cab269bd714d4b564be22788ebbf
https://doi.org/10.3390/genes12020170
https://doi.org/10.3390/genes12020170
Publikováno v:
Biophysical Journal. 111:2202-2213
Contractile rings play critical roles in a number of biological processes, including oogenesis, wound healing, and cytokinesis. In many cases, the activity of motor proteins such as nonmuscle myosins is required for appropriate constriction of these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::824386ba390ec0773b7104b9ab762351
https://doi.org/10.1016/j.bpj.2016.10.011
https://doi.org/10.1016/j.bpj.2016.10.011
Autor:
David B. Pilgrim, Francesca Jean
Publikováno v:
European journal of cell biology. 96(7)
Constructing the distinct subcellular environment of the cilium relies in a large part upon intraflagellar transport (IFT) proteins, which traffic cargo both to and within the cilium. However, evidence from the last 10 years suggests that IFT alone i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a7fc7d41a86424b640da6c356d15810
https://pubmed.ncbi.nlm.nih.gov/28935136
https://pubmed.ncbi.nlm.nih.gov/28935136
Autor:
J. Layne Myhre, David B. Pilgrim
Publikováno v:
The Anatomical Record. 297:1604-1614
The sarcomeres of striated muscle are among the most elaborate and dynamic eukaryotic cellular protein machinery, and the mechanisms by which these semicrystalline filament networks are initially patterned and assembled remain contentious. In additio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f280691ec5fad05ddee3d089865a2a8b
https://doi.org/10.1002/ar.22987
https://doi.org/10.1002/ar.22987