Zobrazeno 1 - 10
of 79
pro vyhledávání: '"David B Pearse"'
Publikováno v:
Canadian Respiratory Journal, Vol 21, Iss 6, Pp 337-340 (2014)
Given that Churg-Strauss syndrome is a systemic small-vessel vasculitis, it is not usually considered in patients who present with massive hemoptysis, which is typically caused by bronchiectasis, cancer or, in some cases, aberrant bronchial arteries.
Externí odkaz:
https://doaj.org/article/66a8cd797e3642e9aebb85614cd9ab7c
Autor:
Ifeanyi U Anidi, Laura E Servinsky, Otgonchimeg Rentsendorj, R Scott Stephens, Alan L Scott, David B Pearse
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71010 (2013)
Severe malaria can trigger acute lung injury characterized by pulmonary edema resulting from increased endothelial permeability. However, the mechanism through which lung fluid conductance is altered during malaria remains unclear. To define the role
Externí odkaz:
https://doaj.org/article/12b69bb1112444feb318dec8c3658663
Autor:
Varodom Charoensawan, Kelly S. Schweitzer, Lucas A. Gillenwater, Constance A. Griffin, Irina Bronova, David B. Pearse, Raluca Yonescu, Irina Petrache, Natalia I. Rush, Russel P. Bowler, Sonia M. Leach, Kevin Ni, Evgeny Berdyshev, Natini Jinawath
Publikováno v:
JCI Insight
Cigarette smoking (CS) and genetic susceptibility determine the risk for development, progression, and severity of chronic obstructive pulmonary diseases (COPD). We posited that an incidental balanced reciprocal chromosomal translocation was linked t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3447171943464b1ef966e36e0023c8b9
https://pubmed.ncbi.nlm.nih.gov/32573489
https://pubmed.ncbi.nlm.nih.gov/32573489
Autor:
Jeffrey M. Dodd-o, Alan L. Scott, Joel Zaldumbide, Clark Undem, David B. Pearse, Otgonchimeg Rentsendorj, Jose Reyes, Laura Servinsky, Sruti Modekurty, Karthik Suresh, Larissa A. Shimoda
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 312:L143-L153
Elevated levels of reactive oxygen species and intracellular Ca2+ play a key role in endothelial barrier dysfunction in acute lung injury. We previously showed that H2O2-induced increases in intracellular calcium concentrations ([Ca2+]i) in lung micr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40c5e15ffba323ad8c497672e76fd312
https://doi.org/10.1152/ajplung.00361.2016
https://doi.org/10.1152/ajplung.00361.2016
Autor:
Nicholas Ladikos, Renee Blanding, Panagis Galiatsatos, David B. Pearse, David M. Yousem, S. Sonia Qasba, Jo Ellen Harris, Morgan J. Katz, Trish M. Perl, Noya Galai, Geeta Sood, Mark Landrum, Amy M. Knight, Christina Wilson, Richard Bennett, Saranya Seetharaman
Publikováno v:
The American journal of medicine. 132(7)
Purpose The objective of this study was to assess whether earlier antibiotic administration in patients with systemic inflammatory response syndrome (SIRS) and evidence of organ dysfunction identified through electronic alerts improves patient mortal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::926210888f94792b7b82f824fe4b227b
https://pubmed.ncbi.nlm.nih.gov/31606064
https://pubmed.ncbi.nlm.nih.gov/31606064
Autor:
Laura E. Servinsky, David B. Pearse, Syeda Baksh, Michael J. Caterina, Karthik Suresh, Clark Undem, Larissa A. Shimoda, Jose Reyes
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 309:L1467-L1477
In acute respiratory distress syndrome, both reactive oxygen species (ROS) and increased intracellular calcium ([Ca2+]i) are thought to play important roles in promoting endothelial paracellular permeability, but the mechanisms linking ROS and [Ca2+]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcb363dcdc9ebefba42a56be61bdf2ec
https://doi.org/10.1152/ajplung.00275.2015
https://doi.org/10.1152/ajplung.00275.2015
Publikováno v:
Journal of Leukocyte Biology. 96:907-915
PDE2A is a dual-function PDE that is stimulated by cGMP to hydrolyze cAMP preferentially. In a two-hit model of ALI, we found previously that PDE2A decreased lung cAMP, up-regulated lung iNOS, and exacerbated ALI. Recent data suggest that macrophage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee809be6bfbdb11314120e53cd4015de
https://doi.org/10.1189/jlb.3a0314-152r
https://doi.org/10.1189/jlb.3a0314-152r
Autor:
Kevin J. Psoter, Albert Agbanlog, Paul Ortiz, Cyrus Mazidi, Jacob Sama, Seema Nayak, Jillian Irwin, Hardin Pantle, Mary Masterson, Robert Jurao, Sam Stern, Jennifer Townsend, Victoria Adams-Sommer, Michael Melgar, Elsen Jacob, Robin McKenzie, David B. Pearse, Flora Kisuule, Panagis Galiatsatos, Catherine Kiruthi
Publikováno v:
Open Forum Infectious Diseases
Background European trials using procalcitonin (PCT)-guided antibiotic therapy for patients with lower respiratory tract infections (LRTI) have resulted in significant reductions in antibiotic use without increasing adverse outcomes. Few prospective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11e08e410db3a429ad0d8297acd44b80
https://doi.org/10.1093/ofid/ofy210.1624
https://doi.org/10.1093/ofid/ofy210.1624
Publikováno v:
Canadian Respiratory Journal, Vol 21, Iss 6, Pp 337-340 (2014)
Given that Churg-Strauss syndrome is a systemic small-vessel vasculitis, it is not usually considered in patients who present with massive hemoptysis, which is typically caused by bronchiectasis, cancer or, in some cases, aberrant bronchial arteries.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba2fac7baa26d57dba9829658709980d
https://doaj.org/article/66a8cd797e3642e9aebb85614cd9ab7c
https://doaj.org/article/66a8cd797e3642e9aebb85614cd9ab7c
Publikováno v:
Chest. 144:1964-1968
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f199c810d1141df61baa730e680b05ef
https://doi.org/10.1378/chest.13-0902
https://doi.org/10.1378/chest.13-0902