Zobrazeno 1 - 10
of 32
pro vyhledávání: '"David B Kastner"'
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 11, p e1006560 (2018)
To transmit information efficiently in a changing environment, the retina adapts to visual contrast by adjusting its gain, latency and mean response. Additionally, the temporal frequency selectivity, or bandwidth changes to encode the absolute intens
Externí odkaz:
https://doaj.org/article/18eca5bd598948838ca78afc9c1010b0
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 8, p e1006291 (2018)
A central challenge in sensory neuroscience involves understanding how neural circuits shape computations across cascaded cell layers. Here we attempt to reconstruct the response properties of experimentally unobserved neurons in the interior of a mu
Externí odkaz:
https://doaj.org/article/77bfc50ae8204262b7b178d74520ec81
Autor:
David B. Kastner, Eric A. Miller, Zhuonan Yang, Demetris K. Roumis, Daniel F. Liu, Loren M. Frank, Peter Dayan
Publikováno v:
Cell Reports
Cell reports, vol 39, iss 3
Cell reports, vol 39, iss 3
Understanding the complexities of behavior is necessary to interpret neurophysiological data and establish animal models of neuropsychiatric disease. This understanding requires knowledge of the underlying information-processing structure-something o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4b71745e565bd6863ab4beca54ddafe
https://hdl.handle.net/21.11116/0000-0007-49D3-9
https://hdl.handle.net/21.11116/0000-0007-49D3-9
Autor:
Aron M. Geurts, David B. Kastner, Melinda R. Dwinell, Loren M. Frank, Michael Grzybowski, Eric A. Miller
Publikováno v:
Molecular Psychiatry
Molecular psychiatry, vol 26, iss 6
Molecular psychiatry, vol 26, iss 6
Measuring animal behavior in the context of experimental manipulation is critical for modeling, and understanding neuropsychiatric disease. Prepulse inhibition of the acoustic startle response (PPI) is a behavioral phenomenon studied extensively for
Publikováno v:
Cell reports, vol 38, iss 5
Neural circuits function in the face of changing inputs, either caused by normal variation in stimuli or by cell death. To maintain their ability to perform essential computations with partial inputs, neural circuits make modifications. Here, we stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::985763b1c87556c36ce029cfe4b22703
https://escholarship.org/uc/item/0fm75301
https://escholarship.org/uc/item/0fm75301
Publikováno v:
CISS
The retina provides an excellent system for understanding the trade-offs that influence distributed information processing across multiple neuron types. We focus here on the problem faced by the visual system of allocating a limited number neurons to
Autor:
Loren M. Frank, Michael E. Coulter, David B. Kastner, Daniela A. Astudillo Maya, Daniel F. Liu, Demetris K. Roumis, Uri T. Eden, Anna K. Gillespie, Eric L. Denovellis
Executing memory-guided behavior requires both the storage of information about experience and the later recall of that information to inform choices. Awake hippocampal replay, when hippocampal neural ensembles briefly reactivate a representation rel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fc940359a85907e64b0366c17d5a2d6
https://doi.org/10.1101/2021.03.09.434621
https://doi.org/10.1101/2021.03.09.434621
Autor:
Rhino Nevers, Clay Smyth, Zhounan Yang, Dilworth Y. Parkinson, Loren M. Frank, Viktor Kharazia, Daniela A Astudillo-Maya, Cristofer M Holobetz, David B. Kastner, Luca Della Santina, Greer M Williams
Publikováno v:
Scientific reports, vol 10, iss 1
Scientific Reports
Scientific Reports
Anatomic evaluation is an important aspect of many studies in neuroscience; however, it often lacks information about the three-dimensional structure of the brain. Micro-CT imaging provides an excellent, nondestructive, method for the evaluation of b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dcb4f309256838f5ea97bd1fe8b109c
https://escholarship.org/uc/item/2gb2v67p
https://escholarship.org/uc/item/2gb2v67p
Autor:
Yien-Ming Kuo, Ivan A. Anastassov, Felice A. Dunn, David B. Kastner, Rachel A. Care, Luca Della Santina
Publikováno v:
Cell reports, vol 31, iss 10
Cell reports
Cell reports
SUMMARY Loss of primary neuronal inputs inevitably strikes every neural circuit. The deafferented circuit could propagate, amplify, or mitigate input loss, thus affecting the circuit’s output. How the deafferented circuit contributes to the effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93f187d8314cb74f2cb5045daaca4b35
https://escholarship.org/uc/item/0j51h1k6
https://escholarship.org/uc/item/0j51h1k6
Publikováno v:
The Journal of Neuroscience
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 40, iss 38
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 40, iss 38
Animal behavior provides context for understanding disease models and physiology. However, that behavior is often characterized subjectively, creating opportunity for misinterpretation and misunderstanding. For example, spatial alternation tasks are