Zobrazeno 1 - 10
of 129
pro vyhledávání: '"David B Berkowitz"'
Autor:
Stephany M. Ramos de Dios, Jared L. Hass, Danielle L. Graham, Nivesh Kumar, Aina E. Antony, Martha D. Morton, David B. Berkowitz
Publikováno v:
Journal of the American Chemical Society. 145:3158-3174
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18bc78a6a8cc3a92f16a24a516babcee
https://doi.org/10.1021/jacs.2c12774
https://doi.org/10.1021/jacs.2c12774
Publikováno v:
Frontiers in Molecular Biosciences, Vol 6 (2019)
Serine racemase (SR) is the first racemase enzyme to be identified in human biology and converts L-serine to D-serine, an important neuronal signaling molecule that serves as a co-agonist of the NMDA (N-methyl-D-aspartate) receptor. This overview des
Externí odkaz:
https://doaj.org/article/90b0dd63e5c441dda4ace24b804a43e3
Autor:
Robert Moore, Bhanwar Lal Puniya, Robert Powers, Chittibabu Guda, Kenneth W. Bayles, David B. Berkowitz, Tomáš Helikar
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-1 (2021)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/5178e14d927c4301946de209cb861658
Autor:
Christopher D. McCune, Su Jing Chan, Matthew L. Beio, Weijun Shen, Woo Jin Chung, Laura M. Szczesniak, Chou Chai, Shu Qing Koh, Peter T.-H. Wong, David B. Berkowitz
Publikováno v:
ACS Central Science, Vol 2, Iss 4, Pp 242-252 (2016)
Externí odkaz:
https://doaj.org/article/88b26ca81d394fe68cad2b321cdd807f
Autor:
Stephany M. Ramos De Dios, Virendra K. Tiwari, Christopher D. McCune, Ranjeet A. Dhokale, David B. Berkowitz
Publikováno v:
Chemical reviews. 122(16)
Reaction discovery and catalyst screening lie at the heart of synthetic organic chemistry. While there are efforts at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6fe6d8579ed66e4b2092fbb4b32a257
https://pubmed.ncbi.nlm.nih.gov/35904776
https://pubmed.ncbi.nlm.nih.gov/35904776
Publikováno v:
Synlett. 31:237-247
Described is a physical organic study of the reduction of three sets of carbonyl compounds by the NADPH-dependent enzyme Clostridium acetobutylicum alcohol dehydrogenase (CaADH). Previous studies in our group have shown this enzyme to display broad s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::271d368743d551fc67e2f0fb3f0ec4f7
https://doi.org/10.1055/s-0039-1691576
https://doi.org/10.1055/s-0039-1691576
Autor:
Sushil K. Shakyawar, Nitish K. Mishra, Neetha N. Vellichirammal, Lynnette Cary, Tomáš Helikar, Robert Powers, Rebecca E. Oberley-Deegan, David B. Berkowitz, Kenneth W. Bayles, Vijay K. Singh, Chittibabu Guda
Publikováno v:
Radiat Res
Increasing utilization of nuclear power enhances the risks associated with industrial accidents, occupational hazards, and the threat of nuclear terrorism. Exposure to ionizing radiation interferes with genomic stability and gene expression resulting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c3eea5a434c4697e28657b57d330ad5
https://pubmed.ncbi.nlm.nih.gov/36368026
https://pubmed.ncbi.nlm.nih.gov/36368026
Autor:
Medhanjali Dasgupta, Dominik Budday, Saulo H.P. de Oliveira, Peter Madzelan, Darya Marchany-Rivera, Javier Seravalli, Brandon Hayes, Raymond G. Sierra, Sebastian Boutet, Mark Hunter, Roberto Alonso-Mori, Alexander Batyuk, Jennifer Wierman, Artem Lyubimov, Aaron S. Brewster, Nicholas K. Sauter, Gregory A. Applegate, Virendra K. Tiwari, David B. Berkowitz, Michael C. Thompson, Aina Cohen, James S. Fraser, Michael E. Wall, Henry van den Bedem, Mark A. Wilson
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 116, iss 51
Proc Natl Acad Sci U S A
Proc Natl Acad Sci U S A
Summary ParagraphProtein dynamics play an important role in enzyme catalysis1-4. Many enzymes form covalent catalytic intermediates that can alter enzyme structure and conformational dynamics5,6. How these changes in enzyme structure and dynamics fac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b7d06cdb8d8ec5a5bf846475f95d325
https://doi.org/10.1073/pnas.1901864116
https://doi.org/10.1073/pnas.1901864116
Publikováno v:
Organic Letters. 21:9846-9851
A convenient synthetic route to α,α-difluoroalkylphosphonates is described. Structurally diverse aldehydes are condensed with LiF2CP(O)(OCH2CH═CH2)2. The resultant alcohols are captured as the pentafluorophenyl thionocarbonates and efficiently de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d2c950ff2e274a412d8215c67ff8147
https://doi.org/10.1021/acs.orglett.9b03707
https://doi.org/10.1021/acs.orglett.9b03707
Publikováno v:
Journal of Organic Chemistry
Journal of Organic Chemistry, American Chemical Society, 2021, 86 (9), pp.6494-6503. ⟨10.1021/acs.joc.1c00326⟩
Journal of Organic Chemistry, American Chemical Society, 2021, 86 (9), pp.6494-6503. ⟨10.1021/acs.joc.1c00326⟩
International audience; A formal synthesis of the antiviral drug (−)-oseltamivir (Tamiflu) has been accomplished starting from m-anisic acid via a dissolving metal or electrochemical Birch reduction. The correct absolute stereochemistry is efficien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e37b28cc907d559e99cdff3b9cb963e
https://pubmed.ncbi.nlm.nih.gov/33857378
https://pubmed.ncbi.nlm.nih.gov/33857378