Výsledky vyhledávání - "David B Agus"

Akademický článek

The Long-Term Benefits of Increased Aspirin Use by At-Risk Americans Aged 50 and Older.

Autor: David B Agus, Étienne Gaudette, Dana P Goldman, Andrew Messali

Publikováno v: PLoS ONE, Vol 11, Iss 11, p e0166103 (2016)

The usefulness of aspirin to defend against cardiovascular disease in both primary and secondary settings is well recognized by the medical profession. Multiple studies also have found that daily aspirin significantly reduces cancer incidence and mor

Externí odkaz: https://doaj.org/article/c03f0caa6bb5477abb8631a7196f5b25

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Akademický článek

Impact of protein stability, cellular localization, and abundance on proteomic detection of tumor-derived proteins in plasma.

Autor: Qiaojun Fang, Kian Kani, Vitor M Faca, Wenxuan Zhang, Qing Zhang, Anjali Jain, Sam Hanash, David B Agus, Martin W McIntosh, Parag Mallick

Publikováno v: PLoS ONE, Vol 6, Iss 7, p e23090 (2011)

Tumor-derived, circulating proteins are potentially useful as biomarkers for detection of cancer, for monitoring of disease progression, regression and recurrence, and for assessment of therapeutic response. Here we interrogated how a protein's stabi

Externí odkaz: https://doaj.org/article/525cffbce3a746359bd7ba210a490e69

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Akademický článek

Deep learning-enabled breast cancer hormonal receptor status determination from base-level H&E stains

Autor: Nikhil Naik, Ali Madani, Andre Esteva, Nitish Shirish Keskar, Michael F. Press, Daniel Ruderman, David B. Agus, Richard Socher

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)

Determination of estrogen receptor status (ERS) in breast cancer tissue requires immunohistochemistry, which is sensitive to the vagaries of sample processing and the subjectivity of pathologists. Here the authors present a deep learning model that d

Externí odkaz: https://doaj.org/article/169f3fde02b44f04a44160ad8fb94419

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Akademický článek

Monitoring dynamic cytotoxic chemotherapy response in castration-resistant prostate cancer using plasma cell-free DNA (cfDNA)

Autor: Katherin Patsch, Naim Matasci, Anjana Soundararajan, Patricia Diaz, David B. Agus, Daniel Ruderman, Mitchell E. Gross

Publikováno v: BMC Research Notes, Vol 12, Iss 1, Pp 1-7 (2019)

Abstract Objective Cell-free DNA (cfDNA) is an attractive cancer biomarker, as it is thought to reflect a component of the underlying genetic makeup of the tumor and is readily accessible in serial fashion. Because chemotherapy regimens are expected

Externí odkaz: https://doaj.org/article/b6b28c1fefbe4213905ffdd9b4b4e7d9

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