Zobrazeno 1 - 10
of 13
pro vyhledávání: '"David Aguilar-Recarte"'
Autor:
Mona Peyman, Anna Babin-Ebell, Rosalía Rodríguez-Rodríguez, Matilde Rigon, David Aguilar-Recarte, Joan Villarroya, Anna Planavila, Francesc Villarroya, Xavier Palomer, Emma Barroso, Manuel Vázquez-Carrera
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-11 (2024)
Abstract Background Endoplasmic reticulum (ER) stress-mediated increases in the hepatic levels of the very low-density lipoprotein (VLDL) receptor (VLDLR) promote hepatic steatosis by increasing the delivery of triglyceride-rich lipoproteins to the l
Externí odkaz:
https://doaj.org/article/aa50fcc0fdab48139a2c97688557bd98
Autor:
Meijian Zhang, Emma Barroso, Maria Ruart, Lucía Peña, Mona Peyman, David Aguilar-Recarte, Marta Montori-Grau, Patricia Rada, Clara Cugat, Carla Montironi, Mohammad Zarei, Javier Jurado-Aguilar, Antoni Camins, Jesús Balsinde, Ángela M. Valverde, Walter Wahli, Xavier Palomer, Manuel Vázquez-Carrera
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 167, Iss , Pp 115623- (2023)
Elafibranor is a dual peroxisome proliferator-activated receptor (PPAR)α and β/δ agonist that has reached a phase III clinical trial for the treatment of metabolic dysfunction-associated steatotic liver disease (MASLD). Here, we examined the effec
Externí odkaz:
https://doaj.org/article/482a0be0b5064142a7d350a00b86da03
Autor:
Marta Montori-Grau, David Aguilar-Recarte, Mohammad Zarei, Javier Pizarro-Delgado, Xavier Palomer, Manuel Vázquez-Carrera
Publikováno v:
Cell Communication and Signaling, Vol 20, Iss 1, Pp 1-14 (2022)
Abstract Background Peroxisome proliferator-activated receptor γ (PPARγ) coactivator 1α (PGC-1α) downregulation in skeletal muscle contributes to insulin resistance and type 2 diabetes mellitus. Here, we examined the effects of endoplasmic reticu
Externí odkaz:
https://doaj.org/article/451a5ea643dc4a84b44b5ac0d9421f14
Autor:
David Aguilar-Recarte, Emma Barroso, Anna Gumà, Javier Pizarro-Delgado, Lucía Peña, Maria Ruart, Xavier Palomer, Walter Wahli, Manuel Vázquez-Carrera
Publikováno v:
Cell Reports, Vol 36, Iss 6, Pp 109501- (2021)
Summary: Peroxisome proliferator-activated receptor β/δ (PPARβ/δ) activates AMP-activated protein kinase (AMPK) and plays a crucial role in glucose and lipid metabolism. Here, we examine whether PPARβ/δ activation effects depend on growth diffe
Externí odkaz:
https://doaj.org/article/b6f0fb8048d340e8be15dc85700ffd26
Publikováno v:
Trends in Endocrinology & Metabolism. 33:741-754
Although a large number of drugs are available for the treatment of type 2 diabetes mellitus (T2DM), many patients do not achieve adequate disease control despite adhering to medication. Recent findings indicate that the pharmacological modulation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::467196f960febc4eb58f4ae37fb0a526
https://doi.org/10.1016/j.tem.2022.08.004
https://doi.org/10.1016/j.tem.2022.08.004
Autor:
Manuel Vázquez-Carrera, Raquel García, David Aguilar-Recarte, J. Francisco Nistal, Xavier Palomer
Publikováno v:
Trends in Molecular Medicine. 27:554-571
Diabetic cardiomyopathy is the leading cause of death among people with diabetes. Despite its severity and poor prognosis, there are currently no approved specific drugs to prevent or even treat diabetic cardiomyopathy. There is a need to understand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a573440146d81e35fc25992352b8af02
https://doi.org/10.1016/j.molmed.2021.03.004
https://doi.org/10.1016/j.molmed.2021.03.004
Autor:
David Aguilar-Recarte, Emma Barroso, Meijian Zhang, Patricia Rada, Javier Pizarro-Delgado, Lucía Peña, Xavier Palomer, Ángela M. Valverde, Walter Wahli, Manuel Vázquez-Carrera
Publikováno v:
Pharmacological research. 187
Metformin, the most prescribed drug for the treatment of type 2 diabetes mellitus, has been recently reported to promote weight loss by upregulating the anorectic cytokine growth differentiation factor 15 (GDF15). Since the antidiabetic effects of me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9bb1482b85c796ccca40ee3d794f9e4
https://pubmed.ncbi.nlm.nih.gov/36435271
https://pubmed.ncbi.nlm.nih.gov/36435271
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, MDPI, 2021, 22 (16), pp.8555. ⟨10.3390/ijms22168555⟩
Dipòsit Digital de la UB
Universidad de Barcelona
International Journal of Molecular Sciences, Vol 22, Iss 8555, p 8555 (2021)
International Journal of Molecular Sciences, MDPI, 2021, 22 (16), pp.8555. ⟨10.3390/ijms22168555⟩
Dipòsit Digital de la UB
Universidad de Barcelona
International Journal of Molecular Sciences, Vol 22, Iss 8555, p 8555 (2021)
International audience; The current treatment options for type 2 diabetes mellitus do not adequately control the disease in many patients. Consequently, there is a need for new drugs to prevent and treat type 2 diabetes mellitus. Among the new potent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::228348759ce0944f9a4b3c79acc11c8b
http://hdl.handle.net/2445/183848
http://hdl.handle.net/2445/183848
Autor:
David Aguilar-Recarte, Emma Barroso, Javier Pizarro-Delgado, Lucía Peña, Maria Ruart, Xavier Palomer, Walter Wahli, Manuel Vázquez-Carrera
Peroxisome proliferator-activated receptor β/δ(PPARβ/δ) activates AMP-activated protein kinase (AMPK) and plays a crucial role in glucose and lipid metabolism. Here, we examined whether the beneficial effects of PPARβ/δ activation depended on g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68c20f8ac1f1b1ee299ff0dcf158f951
https://doi.org/10.21203/rs.3.rs-58957/v1
https://doi.org/10.21203/rs.3.rs-58957/v1
Publikováno v:
Clinica e investigacion en arteriosclerosis : publicacion oficial de la Sociedad Espanola de Arteriosclerosis. 33(2)
Apolipoprotein C-III (apoC-III) is a small protein that is predominantly synthesized in the liver and mainly resides at the surface of triglyceride-rich lipoproteins. Its expression is upregulated by glucose and reduced by insulin, with enhanced apoC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::223e4b01df9fefdd072f281b84879be0
https://pubmed.ncbi.nlm.nih.gov/33303217
https://pubmed.ncbi.nlm.nih.gov/33303217