Zobrazeno 1 - 10
of 27
pro vyhledávání: '"David Aguado-Llera"'
Autor:
David Aguado-Llera, Tewfik Hamidi, Rosa Doménech, David Pantoja-Uceda, Meritxell Gironella, Jorge Santoro, Adrián Velázquez-Campoy, José L Neira, Juan L Iovanna
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e78101 (2013)
The stress protein Nupr1 is a highly basic, multifunctional, intrinsically disordered protein (IDP). MSL1 is a histone acetyl transferase-associated protein, known to intervene in the dosage compensation complex (DCC). In this work, we show that both
Externí odkaz:
https://doaj.org/article/5d92fd0d15044e9892b0fd93e7dfb61c
Autor:
David Aguado-Llera, Ana Isabel Martínez-Gómez, Jesús Prieto, Marco Marenchino, José Angel Traverso, Javier Gómez, Ana Chueca, José L Neira
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e17068 (2011)
Thioredoxins (TRXs) are ubiquitous proteins involved in redox processes. About forty genes encode TRX or TRX-related proteins in plants, grouped in different families according to their subcellular localization. For instance, the h-type TRXs are loca
Externí odkaz:
https://doaj.org/article/16f45d4bf57b471d8be65ff11b6f14ba
Autor:
Eduardo Arilla-Ferreiro, David Aguado-Llera, Vicente Barrios, Cristina Fernández-Mendívil, Sandra Canelles, Jesús Argente, Laura M. Frago, Manuela G. López
Publikováno v:
Neuropharmacology. 151
Glycine-proline-glutamate (GPE) is a cleaved tripeptide of IGF-I that can be processed to cycloprolylglycine (cPG) in the brain. IGF-I protects the hippocampal somatostatinergic system from β-amyloid (Aβ) insult and although neither IGF-I-derived p
Autor:
Jesús Argente, David Aguado-Llera, Sandra Canelles, Laura M. Frago, Julie A. Chowen, Vicente Barrios, Eduardo Arilla
Publikováno v:
Neuroscience. 374
Somatostatin (SRIF), a neuropeptide highly distributed in the hippocampus and involved in learning and memory, is markedly reduced in the brain of Alzheimer’s disease patients. The effects of insulin-like growth factor-I (IGF-I) against β amyloid
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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E2 ubiquitin conjugases are ∼ 20 kDa enzymes involved in ubiquitination processes in eukaryotes. The E2s are responsible for the transference of ubiquitin (Ub) to E3 enzymes, which finally transfer Ub to diverse target proteins, labelling them for
Autor:
Vicente Barrios, Alberto M. Hernández-Pinto, L. Puebla-Jiménez, David Aguado-Llera, Eduardo Arilla-Ferreiro
Publikováno v:
Neurochemistry International. 58:22-34
Here, we assessed the effects of acute experimental autoimmune encephalomyelitis (EAE) on the rat hippocampal somatostatinergic system and whether administration of an ethanolamine phosphate salt could prevent the appearance of the clinical signs and
Autor:
Luis Alfonso Martínez-Cruz, Javier Gómez, Inmaculada Gómez-García, Iker Oyenarte, Paz Sevilla, David Aguado-Llera, José Antonio Encinar, José L. Neira, Francisco García-Blanco
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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Nucleotide-binding cystathionine -synthase (CBS) domains function as regulatory motifs in several proteins distributed through all kingdoms of life. This function has been proposed based on their affinity for adenosyl- derivatives, although the exact
Publikováno v:
FEBS Letters. 584:4485-4489
The cystathionine beta-synthase (CBS) domains function as regulatory motifs in several proteins. Elucidating how CBS domains exactly work is relevant because several genetic human diseases have been associated with mutations in those motifs. Here, we
Autor:
Francisco Santoyo-Gonzalez, José L. Neira, Francisco Javier Lopez-Jaramillo, Ana Chueca, Antonio Jesús Serrato, David Aguado-Llera, Mariam Sahrawy, Mariano Ortega-Muñoz, José A. Traverso
Publikováno v:
Journal of Plant Physiology. 167:423-429
The largest group of plant thioredoxins (TRXs) consists of the so-called h-type; their great number raises questions about their specific or redundant roles in plant cells. Pisum sativum thioredoxin h1 (PsTRXh1) and Pisum sativum thioredoxin h2 (PsTR
Autor:
Jesús Argente, David Aguado-Llera, Laura M. Frago, L. Puebla-Jiménez, Julie A. Chowen, Eduardo Arilla-Ferreiro, Vicente Barrios
Publikováno v:
Neurobiology of Aging. 28:1396-1409
Estradiol prevents amyloid-beta peptide (Abeta)-induced cell death through estrogen receptors (ERs) and modulates somatostatin (SRIF) responsiveness in the rat brain. As intracerebroventricular (ICV) Abeta25-35 administration reduces SRIFergic tone i