Zobrazeno 1 - 10 of 17 pro vyhledávání: '"David Adámek"'
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Oligomeric Architecture of Mouse Activating Nkrp1 Receptors on Living Cells
Autor: Daniel Rozbeský, Zdeněk Kukačka, David Adámek, Ljubina Adámková, Petr Novák, Marek Cebecauer, Zuzana Kvíčalová
Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 20, Iss 8, p 1884 (2019)
Volume 20
Issue 8
Mouse activating Nkrp1 proteins are commonly described as type II transmembrane receptors with disulfide-linked homodimeric structure. Their function and the manner in which Nkrp1 proteins of mouse strain (C57BL/6) oligomerize are still poorly unders
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33832cb8192cda71fb5353795040152a
https://pubmed.ncbi.nlm.nih.gov/30995786
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2
Solution structure of the lymphocyte receptor Nkrp1a reveals a distinct conformation of the long loop region as compared to in the crystal structure
Autor: Josef Chmelík, Petr Novák, Daniel Rozbeský, David Adámek, Eliska Pospisilova
Publikováno v: Proteins: Structure, Function, and Bioinformatics. 84:1304-1311
Mouse Nkrp1a receptor is a C-type lectin-like receptor expressed on the surface of natural killer cells that play an important role against virally infected and tumor cells. The recently solved crystal structure of Nkrp1a raises questions about a lon
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::76a8752c648b3b82022969d653368582
https://doi.org/10.1002/prot.25078
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3
Solution structure of the lymphocyte receptor Nkrp1a reveals a distinct conformation of the long loop region as compared to in the crystal structure
Autor: Daniel, Rozbeský, David, Adámek, Eliška, Pospíšilová, Petr, Novák, Josef, Chmelík
Publikováno v: Proteins. 84(9)
Mouse Nkrp1a receptor is a C-type lectin-like receptor expressed on the surface of natural killer cells that play an important role against virally infected and tumor cells. The recently solved crystal structure of Nkrp1a raises questions about a lon
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a74d4f83f856eed9787a63ddc9dc9bc3
https://pubmed.ncbi.nlm.nih.gov/27238500
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5
Enzymatic synthesis of dimeric glycomimetic ligands of NK cell activation receptors
Autor: Lenka Weignerová, Monika Krupová, Anna Drozdová, Birgit Henßen, Kristýna Slámová, Henrik H. Jensen, Karel Křenek, Marek Kuzma, Lothar Elling, Karel Bezouška, Vladimír Křen, David Adámek, Helena Pelantová, Helle Christensen, Pavla Bojarová
Publikováno v: Carbohydrate research. 346(12)
This work reveals new structural relationships in the complex process of the interaction between activation receptors of natural killer cells (rat NKR-P1, human CD69) and novel bivalent carbohydrate glycomimetics. The length, glycosylation pattern an
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4db3b36b9e14344bf4ec108310a3e2f
https://pubmed.ncbi.nlm.nih.gov/21641586
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6
Charged Hexosaminides as New Substrates for beta-N-Acetylhexosaminidase-Catalyzed Synthesis of Immunomodulatory Disaccharides
Autor: Sergio Riva, Helena Pelantová, Vladimír Křen, Natallia Kulik, Pavla Bojarová, David Adámek, Marek Kuzma, Rüdiger Ettrich, Radek Gažák, Kristýna Slámová, Karel Křenek, Karel Bezouška
Publikováno v: Advanced synthesis & catalysis
353 (2011): 2409–2420. doi:10.1002/adsc.201100371
info:cnr-pdr/source/autori:Bojarovà P., Slamovà K., Krened K., Gazak R., Kulik N., Ettrich R., Pelantovà H., Kuzma M., Riva S., Adàmek D., Bezouska K., Kren V./titolo:Charged Hexosaminides as New Substrates for beta-N-Acetylhexosaminidase-Catalyzed Synthesis of Immunomodulatory Disaccharides/doi:10.1002%2Fadsc.201100371/rivista:Advanced synthesis & catalysis (Print)/anno:2011/pagina_da:2409/pagina_a:2420/intervallo_pagine:2409–2420/volume:353
This work is a structure-activity relationship study that investigates the influence of the nature and amount of negative charge in carbohydrate substrates on the affinity of β-N-acetylhexosaminidases, and on the stimulation of natural killer cells.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f3e517f34922accf37149b6f75e2770
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7
Synthesis of Multivalent Glycoconjugates Containing the Immunoactive LELTE Peptide: Effect of Glycosylation on Cellular Activation and Natural Killing by Human Peripheral Blood Mononuclear Cells
Autor: Alan Kadek, Kren, Bossu I, Radek Gazak, Pascal Dumy, Olivier Renaudet, Krenek K, Karel Bezouška, David Adámek, Daniel Kavan, Miroslav Sulc, Vanek O
Publikováno v: Journal of the American Chemical Society
Journal of the American Chemical Society, American Chemical Society, 2010, 132 (19), pp.6800-6808. ⟨10.1021/ja101296t⟩
Pentapeptide diacidic sequence LELTE, derived from the mycobacterial heat shock protein hsp65, has been recently identified as a "danger" signal of the immune system effective via specific binding to the universal leukocyte triggering receptor CD69.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c95fde7b4224a7141288aa0e9d2447b
https://hal.archives-ouvertes.fr/hal-01658615
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8
Carboxylated calixarenes bind strongly to CD69 and protect CD69(+) killer cells from suicidal cell death induced by tumor cell surface ligands
Autor: Kateřina Hofbauerová, Alan Kadek, Petr Man, Karel Křenek, Renata Šnajdrová, Daniel Kavan, David Adámek, Pavla Bojarová, Vladimír Křen, Markéta Vančurová, Karel Bezouška, Pavel Lhoták
Publikováno v: Bioorganicmedicinal chemistry. 18(4)
We have recently identified a new class of high affinity ligands for CD69 leukocyte membrane receptor, carboxylated calixarenes. Of the three compounds investigated here, thiacalix[4]arene had the highest affinity for CD69 in direct binding assays, a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e4397c47a74cd83d04909a5071cc824
https://pubmed.ncbi.nlm.nih.gov/24955474
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9
Retraction notice to 'Carboxylated calixarenes bind strongly to CD69 and protect CD69+ killer cells from suicidal cell death induced by tumor cell surface ligands' [Bioorg. Med. Chem. 18 (4) (2010) 1434–1440]
Autor: Kateřina Hofbauerová, Karel Křenek, David Adámek, Karel Bezouška, Pavel Lhoták, Alan Kadek, Renata Šnajdrová, Daniel Kavan, Pavla Bojarová, Vladimir Kren, Markéta Vančurová, Petr Man
Publikováno v: Bioorganic & Medicinal Chemistry. 22:3227
This article has been retracted: please see Elsevier Policy onArticle Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy).This article has been retracted at the request of the Authors.The above paper describes synthesis of a series of substi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::799826066d568b4d5ed96756c78219e0
https://doi.org/10.1016/j.bmc.2014.05.010
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