Zobrazeno 1 - 5
of 5
pro vyhledávání: '"David A.J. Lecky"'
Publikováno v:
STAR Protocols, Vol 2, Iss 1, Pp 100284- (2021)
Summary: This protocol uses Nr4a1-GFP Nr4a3-Tocky mice to study T cell receptor (TCR) signaling using flow cytometry. It identifies the optimal mouse transgenic status and fluorochromes compatible with the dual reporter. This protocol has application
Externí odkaz:
https://doaj.org/article/522f6c739abd4cc2b2353f7b18c64a89
Autor:
Alastair Copland, Gillian M. Mackie, Lisa Scarfe, David A.J. Lecky, Nancy Gudgeon, Riahne McQuade, Masahiro Ono, Manja Barthel, Wolf-Dietrich Hardt, Hiroshi Ohno, Sarah Dimeloe, David Bending, Kendle M. Maslowski
SummaryBacterial cancer therapy (BCT) is a promising therapeutic for solid tumours.Salmonella entericaTyphimurium (STm) is well-studied amongst bacterial vectors due to advantages in genetic modification and metabolic adaptation. A longstanding parad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cdef840a53f9760c119927240987e121
https://doi.org/10.1101/2023.01.12.523780
https://doi.org/10.1101/2023.01.12.523780
Autor:
Adriana Flores-Langarica, Kendle M. Maslowski, Natasha Thawait, Thomas A.E. Elliot, Alastair Copland, David Bending, Emma K. Jennings, David A.J. Lecky, David C. Wraith
Publikováno v:
Immunity
Summary How T cell receptor (TCR) signal strength modulates T cell function and to what extent this is modified by immune checkpoint blockade (ICB) are key questions in immunology. Using Nr4a3-Tocky mice, we characterized early quantitative and quali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f43037d602993e7db87f2fde608beb0a
https://pubmed.ncbi.nlm.nih.gov/34534438
https://pubmed.ncbi.nlm.nih.gov/34534438
Autor:
Natasha Thawait, Emma K. Jennings, Adriana Flores-Langarica, David Bending, David A.J. Lecky, Thomas A.E. Elliot, David C. Wraith
SummaryHow T cell receptor (TCR) signal strength modulates T cell function and to what extent this is modified by immune checkpoint blockade (ICB) are key questions in immunology. Using Nr4a3-Tocky mice as a digital read-out of NFAT pathway activity,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::447dd01e9dfc4af98625d416b3530239
https://doi.org/10.1101/2021.03.02.431957
https://doi.org/10.1101/2021.03.02.431957
Publikováno v:
STAR Protocols, Vol 2, Iss 1, Pp 100284-(2021)
Summary This protocol uses Nr4a1-GFP Nr4a3-Tocky mice to study T cell receptor (TCR) signaling using flow cytometry. It identifies the optimal mouse transgenic status and fluorochromes compatible with the dual reporter. This protocol has applications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::debfe09ebc45bb835f7a6de728dc0f48
https://doi.org/10.1016/j.xpro.2020.100284
https://doi.org/10.1016/j.xpro.2020.100284