Zobrazeno 1 - 10
of 184
pro vyhledávání: '"David A. Walter"'
Autor:
David M. Walter, Amy C. Gladstein, Katherine R. Doerig, Ramakrishnan Natesan, Saravana G. Baskaran, A. Andrea Gudiel, Keren M. Adler, Jonuelle O. Acosta, Douglas C. Wallace, Irfan A. Asangani, David M. Feldser
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-11 (2023)
SETD2 inactivation leads to heightened mTORC1 signaling, oxidative metabolism and protein synthesis in KRAS-driven mouse models of lung adenocarcinoma, contributing to the understanding of how SETD2 deficiency drives early and widespread tumor growth
Externí odkaz:
https://doaj.org/article/c2c79fc965134987aff07bf0f609c365
Autor:
Christine P. Shen, Benjamin C. Freed, David P. Walter, James C. Perry, Amr F. Barakat, Ahmad Ramy A. Elashery, Kevin S. Shah, Shelby Kutty, Michael McGillion, Fu Siong Ng, Rola Khedraki, Keshav R. Nayak, John D. Rogers, Sanjeev P. Bhavnani
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 8 (2023)
Background Diagnosis of shockable rhythms leading to defibrillation remains integral to improving out‐of‐hospital cardiac arrest outcomes. New machine learning techniques have emerged to diagnose arrhythmias on ECGs. In out‐of‐hospital cardia
Externí odkaz:
https://doaj.org/article/6f0ad7d79864433ea2fd58c7bd9757da
Autor:
Alex Doan, Julia Arand, Diana Gong, Alexandros P. Drainas, Yan Ting Shue, Myung Chang Lee, Shuyuan Zhang, David M. Walter, Andrea C. Chaikovsky, David M. Feldser, Hannes Vogel, Lukas E. Dow, Jan M. Skotheim, Julien Sage
Publikováno v:
PLoS Genetics, Vol 17, Iss 12 (2021)
The retinoblastoma (RB) tumor suppressor is functionally inactivated in a wide range of human tumors where this inactivation promotes tumorigenesis in part by allowing uncontrolled proliferation. RB has been extensively studied, but its mechanisms of
Externí odkaz:
https://doaj.org/article/c1de44c222424f55b2ca3406c6f3a587
Autor:
Frédéric Beaulieu, Wayne Knee, Victoria Nowell, Marla Schwarzfeld, Zoë Lindo, Valerie M. Behan-Pelletier, Lisa Lumley, Monica R. Young, Ian Smith, Heather C. Proctor, Sergei V. Mironov, Terry D. Galloway, David E. Walter, Evert E. Lindquist
Publikováno v:
ZooKeys, Vol 819, Iss , Pp 77-168 (2019)
Summaries of taxonomic knowledge are provided for all acarine groups in Canada, accompanied by references to relevant publications, changes in classification at the family level since 1979, and notes on biology relevant to estimating their diversity.
Externí odkaz:
https://doaj.org/article/e99faf295d674b63a16d9f66d6ecf453
Autor:
Owen D, Seeman, David Evans, Walter
Publikováno v:
Annual Review of Entomology. 68:69-88
Mites are masters at attaching to larger animals, often insects, in a temporary symbiosis called phoresy that allows these tiny animals to exploit patchy resources. In this article, we examine phoresy in the Acari, including those that feed on their
Autor:
David M. Feldser, Travis J. Yates, Michelle Cicchini, Caroline Kim-Kiselak, A. Andrea Gudiel, Charuhas Deshpande, John W. Tobias, Elizabeth L. Buza, Olivia S. Venancio, David M. Walter
Supplementary Table 3: Gene ontology analysis for genes deregulated by both Arid1a and Setd2 loss.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c4fe00ed8f0169ad9244e103bd52315
https://doi.org/10.1158/0008-5472.22416824.v1
https://doi.org/10.1158/0008-5472.22416824.v1
Autor:
David M. Feldser, Travis J. Yates, Michelle Cicchini, Caroline Kim-Kiselak, A. Andrea Gudiel, Charuhas Deshpande, John W. Tobias, Elizabeth L. Buza, Olivia S. Venancio, David M. Walter
Figure legends for supplementary figures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0522efbac8f25153fd945a5558707410
https://doi.org/10.1158/0008-5472.22416839
https://doi.org/10.1158/0008-5472.22416839
Autor:
James L. Riley, Frederic D. Bushman, Mariusz A. Wasik, Amanda Watkins, Sarah Javaid, Kelly M. Zullo, David M. Walter, John W. Tobias, Hong Y. Wang, Qian Zhang, Hong Kong, Fang Wei, John K. Everett, Damian Maseda, David L. Cookmeyer, Jan M. Pawlicki
Fusion genes including NPM–ALK can promote T-cell transformation, but the signals required to drive a healthy T cell to become malignant remain undefined. In this study, we introduce NPM–ALK into primary human T cells and demonstrate induction of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20f6714951d33f88fe6b2fb26cd1da33
https://doi.org/10.1158/0008-5472.c.6513093.v1
https://doi.org/10.1158/0008-5472.c.6513093.v1
Autor:
David M. Feldser, Travis J. Yates, Michelle Cicchini, Caroline Kim-Kiselak, A. Andrea Gudiel, Charuhas Deshpande, John W. Tobias, Elizabeth L. Buza, Olivia S. Venancio, David M. Walter
Chromatin-modifying genes are frequently mutated in human lung adenocarcinoma, but the functional impact of these mutations on disease initiation and progression is not well understood. Using a CRISPR-based approach, we systematically inactivated thr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c4d8f9067a4b248f9769fb74e9a87ec
https://doi.org/10.1158/0008-5472.c.6509660.v1
https://doi.org/10.1158/0008-5472.c.6509660.v1
Autor:
David M. Feldser, Travis J. Yates, Michelle Cicchini, Caroline Kim-Kiselak, A. Andrea Gudiel, Charuhas Deshpande, John W. Tobias, Elizabeth L. Buza, Olivia S. Venancio, David M. Walter
Supplementary Table 2: Ingenuity Pathway Analysis results for Setd2 vs. GFP tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71edf1c1a536f37d85b263f5b21f1fcc
https://doi.org/10.1158/0008-5472.22416827.v1
https://doi.org/10.1158/0008-5472.22416827.v1