Zobrazeno 1 - 10
of 280
pro vyhledávání: '"David A. Sterner"'
Autor:
Brian C. Sanders, Suman Pokhrel, Audrey D. Labbe, Irimpan I. Mathews, Connor J. Cooper, Russell B. Davidson, Gwyndalyn Phillips, Kevin L. Weiss, Qiu Zhang, Hugh O’Neill, Manat Kaur, Jurgen G. Schmidt, Walter Reichard, Surekha Surendranathan, Jyothi Parvathareddy, Lexi Phillips, Christopher Rainville, David E. Sterner, Desigan Kumaran, Babak Andi, Gyorgy Babnigg, Nigel W. Moriarty, Paul D. Adams, Andrzej Joachimiak, Brett L. Hurst, Suresh Kumar, Tauseef R. Butt, Colleen B. Jonsson, Lori Ferrins, Soichi Wakatsuki, Stephanie Galanie, Martha S. Head, Jerry M. Parks
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
The development of direct-acting antivirals to combat COVID-19 remains an important goal. Here the authors design covalent inhibitors that target the papain-like protease from SARS-CoV-2. The most promising inhibitor blocks viral replication in mamma
Externí odkaz:
https://doaj.org/article/fd261a622e08487782f550c5d0f5bc31
Autor:
Liqing Wang, Suresh Kumar, Satinder Dahiya, Feng Wang, Jian Wu, Kheng Newick, Rongxiang Han, Arabinda Samanta, Ulf H. Beier, Tatiana Akimova, Tricia R. Bhatti, Benjamin Nicholson, Mathew P. Kodrasov, Saket Agarwal, David E. Sterner, Wei Gu, Joseph Weinstock, Tauseef R. Butt, Steven M. Albelda, Wayne W. Hancock
Publikováno v:
EBioMedicine, Vol 13, Iss C, Pp 99-112 (2016)
Foxp3+ T-regulatory (Treg) cells are known to suppress protective host immune responses to a wide variety of solid tumors, but their therapeutic targeting is largely restricted to their transient depletion or “secondary” modulation, e.g. using an
Externí odkaz:
https://doaj.org/article/11bbaeb8902a4226b1f3c2291eaa0058
Publikováno v:
Methods in Molecular Biology ISBN: 9781071628027
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21fd14e7bb2eaf306cf6a2e9a62291bd
https://doi.org/10.1007/978-1-0716-2803-4_16
https://doi.org/10.1007/978-1-0716-2803-4_16
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2591
SARS-CoV-2 protease Nsp3 is a therapeutic target for developing anti-SARS-CoV-2 drugs. Nsp3 is a large multi-spanning membrane protein, and its characterization in vitro has been challenging. Here we describe an in vitro assay to characterize the bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::40eb545eddb503c3daff8dca24f82f8f
https://pubmed.ncbi.nlm.nih.gov/36350554
https://pubmed.ncbi.nlm.nih.gov/36350554
Autor:
Brian C. Sanders, Suman Pokhrel, Audrey D. Labbe, Irimpan I. Mathews, Connor J. Cooper, Russell B. Davidson, Gwyndalyn Phillips, Kevin L. Weiss, Qiu Zhang, Hugh O’Neill, Manat Kaur, Jurgen G. Schmidt, Walter Reichard, Surekha Surendranathan, Jyothi Parvathareddy, Lexi Phillips, Christopher Rainville, David E. Sterner, Desigan Kumaran, Babak Andi, Gyorgy Babnigg, Nigel W. Moriarty, Paul D. Adams, Andrzej Joachimiak, Brett L. Hurst, Suresh Kumar, Tauseef R. Butt, Colleen B. Jonsson, Lori Ferrins, Soichi Wakatsuki, Stephanie Galanie, Martha S. Head, Jerry M. Parks
Publikováno v:
Nature communications, vol 14, iss 1
Direct-acting antivirals are needed to combat coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2). The papain-like protease (PLpro) domain of Nsp3 from SARS-CoV-2 is essential for viral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24bd8877103d685e79e5f39fdc0339f5
https://doi.org/10.21203/rs.3.rs-1840200/v1
https://doi.org/10.21203/rs.3.rs-1840200/v1
Autor:
Muhammad Zaman Khan Assir, Ahmadullah Baig, Saad Javed, Suresh Kumar, Asma Abro, Tauseef R. Butt, Christopher Rainville, Muhammad Umer Anwaar, Muhammad Raffey Shabbir, Muhammad Osama, Farjad Adnan, Asad Ur Rehman, David E. Sterner, Rayyan Ahmad Khan, Waseh Ahsan, Syed B. Jamal
Publikováno v:
Computers in Biology and Medicine
The ongoing pandemic of Coronavirus Disease 2019 (COVID-19) has posed a serious threat to global public health. Drug repurposing is a time-efficient approach to finding effective drugs against SARS-CoV-2 in this emergency. Here, we present a robust e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::529bab5b3250acd07310b2ba549f5777
https://doi.org/10.1016/j.compbiomed.2021.105049
https://doi.org/10.1016/j.compbiomed.2021.105049
Author response for 'TAM receptors attenuate murine NK cell responses via E3 ubiquitin ligase Cbl‐b'
Autor:
Taku Kambayashi, Suresh Kumar, Leilani M. Chirino, Michael R. Mattern, Mariko Okumura, David E. Sterner, Tauseef R. Butt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49cf0b6c7638d5db693e472230869f0a
https://doi.org/10.1002/eji.201948204/v2/response1
https://doi.org/10.1002/eji.201948204/v2/response1
Autor:
David E. Sterner, Suresh Kumar, Michael R. Mattern, Leilani M. Chirino, Mariko Okumura, Taku Kambayashi, Tauseef R. Butt
Publikováno v:
Eur J Immunol
TAM receptors (Tyro3, Axl, and Mer) are receptor tyrosine kinases (RTKs) that are expressed by multiple immune cells including NK cells. Although RTKs typically enhance cellular functions, TAM receptor ligation blocks NK-cell activation. The mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb453efea57f7adf2f0ded3db34582d9
https://pubmed.ncbi.nlm.nih.gov/31531847
https://pubmed.ncbi.nlm.nih.gov/31531847
Autor:
Steinn Sigurdsson, Fred Hearty, Kartik Srinivasan, Kyle Kaplan, Steve Osterman, Gabriel Ycas, Emily Lubar, Joe P. Ninan, Jeff Jennings, Eric Levi, Larry Ramsey, Jason T. Wright, Gudmundur Stefansson, Samuel Halverson, Andrew J. Monson, Franklyn Quinlan, Wesley Brand, Christian Schwab, Colin Nitroy, Tyler Anderson, Andrew J. Metcalf, David A. Sterner, Arpita Roy, Scott A. Diddams, Scott B. Papp, David R. Carlson, William D. Cochran, Ryan Terrien, Connor Fredrick, Daniel D. Hickstein, Chad F. Bender, Michael Endl, Shubham Kanodia, Alex Wolszczan, Scott Blakeslee, Paul Robertson, Suvrath Mahadevan
The discovery and characterization of exoplanets around nearby stars are driven by profound scientific questions about the uniqueness of Earth and our solar system, and the conditions under which life could exist elsewhere in our galaxy. Doppler spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::433d1b1a7e96ed83906c2cbb909fd4cf
Autor:
Chad F. Bender, Samuel Halverson, Arpita Roy, Andrew J. Monson, Joe P. Ninan, Suvrath Mahadevan, Gudmundur Stefansson, Emily Lubar, Lawrence W. Ramsey, David E. Sterner, Scott Blakeslee, Paul Robertson, Shubham Kanodia, Frederick R. Hearty
The Habitable-zone Planet Finder (HPF) is a highly stabilized fiber fed precision radial velocity (RV) spectrograph working in the Near Infrared (NIR): 810 - 1280 nm . In this paper we present an overview of the preparation of the optical fibers for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::477f1c48e75c9e66bf8211be61a84556
http://arxiv.org/abs/1808.00557
http://arxiv.org/abs/1808.00557