Zobrazeno 1 - 10
of 83
pro vyhledávání: '"David A. Steinhauer"'
Autor:
Lauren Byrd-Leotis, Nan Jia, Yasuyuki Matsumoto, Dongli Lu, Yoshihiro Kawaoka, David A. Steinhauer, Richard D. Cummings
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract The Madin-Darby canine kidney (MDCK) cell line is an in vitro model for influenza A virus (IAV) infection and propagation. MDCK-SIAT1 (SIAT1) and humanized MDCK (hCK) cell lines are engineered MDCK cells that express N-glycans with elevated
Externí odkaz:
https://doaj.org/article/a25331f87ce64165b15a588479df622c
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 7, p 1541 (2017)
The hemagglutinin (HA) and neuraminidase (NA) glycoproteins of influenza A virus are responsible for the surface interactions of the virion with the host. Entry of the virus is mediated by functions of the HA: binding to cellular receptors and facili
Externí odkaz:
https://doaj.org/article/ba096e52cc9a48afac0fc41937ec48c4
Autor:
Xuemin Chen, He-ying Sun, Chun Yi Lee, Christina A. Rostad, Jessica Trost, Rodrigo B. Abreu, Michael A. Carlock, Jason R. Wilson, Shane Gansebom, Ted M. Ross, David A. Steinhauer, Evan J. Anderson, Larry J. Anderson
Publikováno v:
Virology
Novel cell-based assays were developed to assess antibody-dependence cellular cytotoxicity (ADCC) antibodies against both vaccine and a representative circulation strain HA and NA proteins for the 2014-15 influenza season. The four assays using targe
Autor:
Chao Gao, Jenna L. Lobby, Nan Jia, Alexander N. Wein, Yasuyuki Matsumoto, Jacob E. Kohlmeier, Lauren Byrd-Leotis, Richard D. Cummings, David A. Steinhauer
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
Glycans within human lungs are recognized by many pathogens such as influenza A virus (IAV), yet little is known about their structures. Here we present the first analysis of the N- and O- and glycosphingolipid-glycans from total human lungs, along w
Autor:
Huihui Kong, Laura Rodriguez, Brian R. Wasik, Hanyuan Zhang, Guojun Wang, Yoshihiro Kawaoka, Kuan-Fu Chen, Pamela Freiden, Nicholas Wohlgemuth, David F. Burke, Ashley L. Fink, Sabra L. Klein, Melissa B. Uccellini, Patrick C. Wilson, Karlie Woodard, Sander Herfst, David J. Topham, Angela Danner, Zhen-Ying Liu, Daniel R. Perez, Cheryl A. Jones, John Steel, Philippe Noriel Q. Pascua, Christopher S. Anderson, Anice C. Lowen, Katherine J. Fenstermacher, Lauren Sauer, Victoria A. Meliopoulos, Jeanne Holden-Wiltse, Richard D. Cummings, Yao-Tsun Li, Gabriele Neumann, Malik Peiris, Elena A. Govorkova, Kaori Sakamoto, Michael C. W. Chan, Derek J. Smith, Benjamin L. Miller, Sanjukta Bandyopadhyay, Colin R. Parrish, Subrata Barman, John J. Treanor, Lucas M. Ferreri, Shamika Danzy, Hui Tao, Ian E. H. Voorhees, Ranawaka A.P.M. Perera, Paul G. Thomas, Scott Krauss, David A. Steinhauer, Adolfo García-Sastre, Pilar Blanco-Lobo, Gavin J. D. Smith, Stacey Schultz-Cherry, Phuong T. M. Nguyen, Luis Martinez-Sobrido, Ron A. M. Fouchier, Masato Hatta, Sean Cherry, Brandi Livingston, Marta L. DeDiego, Gongxun Zhong, Mathilde Richard, David J. Pattinson, Mitra Lewis, Bridgett Sharp, Farah El Najjar, Andrew Pekosz, Jasmina M. Luczo, Stephen M. Tompkins, Charles J. Russell, Bindumadhav M. Marathe, Richard E. Rothman, Carole Henry, Lauren Byrd-Leotis, Mark Y. Sangster, Theresa Fitzgerald, Juan Carlos Dib, Shiho Chiba, Shufang Fan, Kathryn Shaw-Saliba, Aitor Nogales, Guohua Yang, Richard J. Webby
Publikováno v:
PLoS Pathogens (print), 16(4). Public Library of Science
PLoS Pathogens
PLoS Pathogens, Vol 16, Iss 4, p e1008409 (2020)
PLoS Pathogens
PLoS Pathogens, Vol 16, Iss 4, p e1008409 (2020)
The continual emergence of novel influenza A strains from non-human hosts requires constant vigilance and the need for ongoing research to identify strains that may pose a human public health risk. Since 1999, canine H3 influenza A viruses (CIVs) hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17cacbabdb58d1c8f6de8ace50f09b62
https://pure.eur.nl/en/publications/1b3e08ab-97d9-478a-b557-32004ce55257
https://pure.eur.nl/en/publications/1b3e08ab-97d9-478a-b557-32004ce55257
Autor:
Sandra F. Cummings, Nan Jia, David A. Steinhauer, Chao Gao, Lauren Byrd-Leotis, Jessica F. Trost, Richard D. Cummings, Jamie Heimburg-Molinaro, Akul Y. Mehta
Publikováno v:
Journal of Virology
Influenza subtype H3N2 viruses have circulated in humans for over 50 years, continuing to cause annual epidemics. Such viruses have undergone antigenic drift in response to immune pressure, reducing the protective effects of preexisting immunity to p
Autor:
Bo Liang, Jessica F. Trost, Wei Wang, Lauren Byrd-Leotis, David A. Steinhauer, Evangeline Agbogu, Summer E. Galloway
Publikováno v:
Virology
Influenza A viruses enter host cells through the endocytic pathway, where acidification triggers conformational changes of the viral hemagglutinin (HA) to drive membrane fusion. During this process, the HA fusion peptide is extruded from its buried p
Autor:
Nan Jia, Richard D. Cummings, Sucharita Dutta, Thomas Braulke, Lauren Byrd-Leotis, Sandra F. Cummings, David A. Steinhauer, Jamie Heimburg-Molinaro, Sven Müller-Loennies, Chao Gao, Jessica F. Trost
Publikováno v:
Science Advances
A novel array of human lung glycans reveals influenza A virus binding to phosphorylated as well as sialylated N-glycans.
Influenza A viruses can bind sialic acid–terminating glycan receptors, and species specificity is often correlated with si
Influenza A viruses can bind sialic acid–terminating glycan receptors, and species specificity is often correlated with si
Autor:
Hailey K. Bennett, Jarod M Hanson, Jackelyn Murray, Nichole Orr-Burks, Joseph Fent, Ming Zhang, Lauren Byrd-Leotis, Ralph A. Tripp, Les P. Jones, Richard D. Cummings, Abhijeet Bakre, Terry Coffey, David A. Steinhauer, Davis E. Bobbitt, Kyle V. Todd, C. S. Kyriakis
Publikováno v:
Veterinary Microbiology. 251:108914
Tracking the genetic diversity and spread of swine influenza viruses (SIVs) in commercial swine farms is central for control and to reduce the potential emergence of SIV reassortants. We analyzed the diversity of SIVs in nasal washes or oral fluids f
Autor:
Lauren Byrd-Leotis, Guadalupe Ayora-Talavera, David A. Steinhauer, Adriana Matos-Patrón, Wendy S. Barclay
Publikováno v:
Virology. 484:15-21
We have analyzed the receptor binding profile of A(H1N1)pdm09 recombinant influenza viruses containing the amino acid substitution D222N which has been associated with a fatal case of infection. This mutation was investigated in conjunction with a se