Zobrazeno 1 - 10
of 33
pro vyhledávání: '"David A. Sorrell"'
Autor:
Dean J. Welsch, Saurabh Saha, Caroline M. Emery, Mark Namchuk, Gary DeCrescenzo, Anna Groover, Kathryn Meshaw, Ramin Samadani, Michael J. Wick, Paul Shapiro, Matthew Fitzgibbon, Gabriel Martinez-Botella, David A. Sorrell, Diane M. Boucher, Michael Hale, Jeffrey J. Roix, Alex M. Aronov, Russell R. Hoover, William Markland, Brinley F. Furey, Ursula A. Germann
Supplementary materials and methods and supplementary figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2691c8ce88b24315d90208e7f0fa7411
https://doi.org/10.1158/1535-7163.22508691.v1
https://doi.org/10.1158/1535-7163.22508691.v1
Autor:
Dean J. Welsch, Saurabh Saha, Caroline M. Emery, Mark Namchuk, Gary DeCrescenzo, Anna Groover, Kathryn Meshaw, Ramin Samadani, Michael J. Wick, Paul Shapiro, Matthew Fitzgibbon, Gabriel Martinez-Botella, David A. Sorrell, Diane M. Boucher, Michael Hale, Jeffrey J. Roix, Alex M. Aronov, Russell R. Hoover, William Markland, Brinley F. Furey, Ursula A. Germann
In SW48 colorectal cells engineered with KRAS alleles, response to paclitaxel was unaltered.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37056904b019df912ca990e86321623e
https://doi.org/10.1158/1535-7163.22508697.v1
https://doi.org/10.1158/1535-7163.22508697.v1
Autor:
Steffen Lawo, Milka B Budnik-Zawilska, Carlos le Sage, Benedict C. S. Cross, Helen N. Pemberton, Steven R Lenger, John McGonigle, Glynn R A Martin, Gaganpreet S Tiwana, David A. Sorrell, Maximilian Blanck
Publikováno v:
Crispr j
The CRISPR Journal
The CRISPR Journal
Functional genomic screening with CRISPR has provided a powerful and precise new way to interrogate the phenotypic consequences of gene manipulation in high-throughput, unbiased analyses. However, some experimental paradigms prove especially challeng
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcf05cc037b2434a79e1d27c6feed171
https://hdl.handle.net/21.11116/0000-000B-2B88-C
https://hdl.handle.net/21.11116/0000-000B-2B88-C
Autor:
Andreas F, Kolb, Christopher, Knowles, Patrikas, Pultinevicius, Jennifer A, Harbottle, Linda, Petrie, Claire, Robinson, David A, Sorrell
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1642
Site-specific recombinases are important tools for the modification of mammalian genomes. In conjunction with viral vectors, they can be utilized to mediate site-specific gene insertions in animals and in cell lines which are difficult to transfect.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d7332360e2f8408fb29423dfe2247f66
https://pubmed.ncbi.nlm.nih.gov/28815498
https://pubmed.ncbi.nlm.nih.gov/28815498
Autor:
David A. Sorrell, Linda Petrie, Andreas F. Kolb, Christopher Knowles, Claire Robinson, Jennifer A Harbottle, Patrikas Pultinevicius
Publikováno v:
Methods in Molecular Biology ISBN: 9781493971671
Site-specific recombinases are important tools for the modification of mammalian genomes. In conjunction with viral vectors, they can be utilized to mediate site-specific gene insertions in animals and in cell lines which are difficult to transfect.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2563f5aead88b094f1abeaff7ae0b819
https://doi.org/10.1007/978-1-4939-7169-5_9
https://doi.org/10.1007/978-1-4939-7169-5_9
Publikováno v:
Technical and Vocational Education and Training: Issues, Concerns and Prospects ISBN: 9783319494838
Bridging the Skills Gap
University of Nottingham Ningbo China
Bridging the Skills Gap
University of Nottingham Ningbo China
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80e01a54373373f3f3e5d889f612170b
https://doi.org/10.1007/978-3-319-49485-2
https://doi.org/10.1007/978-3-319-49485-2
Autor:
Tim M. Scales, Anett Rada-Kovacs, Helen N. Pemberton, Ceri M. Wiggins, Nicola J. McCarthy, Annette S. Little, David A. Sorrell
Publikováno v:
Cancer Research. 79:1927-1927
Cell panel screening of cancer lines grown in standard 2D conditions is a well-established component of the drug discovery toolbox. A sufficiently large cell line panel, reflecting the molecular heterogeneity within a cancer type/sub-type, is require
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aaaf79ec0fa38e3d9b7cff9668927b82
https://doi.org/10.1158/1538-7445.am2019-1927
https://doi.org/10.1158/1538-7445.am2019-1927
Autor:
Claire Neil, C. Bruce A. Whitelaw, Claire Robinson, Simon G. Lillico, Mathias Müller, Caroline Lassnig, David A. Sorrell, Ailsa J Carlisle, Andreas F. Kolb
Publikováno v:
Transgenic Research
Development of the mammary gland requires the coordinated action of proteolytic enzymes during two phases of remodelling. Firstly, new ducts and side-branches thereof need to be established during pregnancy to generate an extensive ductal tree allowi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aba053bbbaadf60614d3ec8ee4a18bd
https://doi.org/10.1007/s11248-012-9654-7
https://doi.org/10.1007/s11248-012-9654-7
Autor:
David A. Sorrell, Sophie Jane Gilbert, Deborah Jane Mason, Anne Vaughan-Thomas, Anthony Joseph Hayes, Philippa Parsons, Mark Bishop, Victor Colin Duance, Rebecca Notman
Publikováno v:
Journal of Biological Chemistry. 286:34986-34997
Type IX collagen is covalently bound to the surface of type II collagen fibrils within the cartilage extracellular matrix. The N-terminal, globular noncollagenous domain (NC4) of the α1(IX) chain protrudes away from the surface of the fibrils into t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f134b526ede276193e0831c691490b86
https://doi.org/10.1074/jbc.m111.238188
https://doi.org/10.1074/jbc.m111.238188
Autor:
David M. Glover, Frederic Scaerou, Emma Easthope, David O. Jones, David A. Sorrell, Amy Emery, Daniella Zheleva, Stacy Lawrence, Mark W. Stockdale
Publikováno v:
SLAS Discovery. 16:925-931
Aurora A kinase is a key regulator of mitosis, which is upregulated in several human cancers, making it a potential target for anticancer therapeutics. Consequently, robust medium- to high-throughput cell-based assays to measure Aurora A kinase activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1544d1b347478bdde0bac8b9e63930fd
https://doi.org/10.1177/1087057111413923
https://doi.org/10.1177/1087057111413923