Zobrazeno 1 - 10
of 17 048
pro vyhledávání: '"David A. Smith"'
Autor:
Iain A. Gillespie, Eleanor Barnes, Ian C. K. Wong, Philippa C. Matthews, Graham S. Cooke, Craig Tipple, Robert C. Elston, Yunhao Liu, David A. Smith, Tingyan Wang, Jim Davies, Kinga A. Várnai, Oliver Freeman, Kenneth K. C. Man, Wallis C. Y. Lau, Ben Glampson, Xing Meng, Eleonora Morais, Sen Liu, Luca Mercuri, Naomi Boxall, Sarah Jenner, Stuart Kendrick, Jane Dong, Dickens Theodore
Publikováno v:
Infectious Diseases and Therapy, Vol 12, Iss 11, Pp 2513-2532 (2023)
Abstract Introduction Chronic hepatitis B virus (HBV) infection is associated with significant global morbidity and mortality. Low treatment rates are observed in patients living with HBV; the reasons for this are unclear. This study sought to descri
Externí odkaz:
https://doaj.org/article/07d54f87960d448e9f684c59b8715e9c
Autor:
Eleni Nastouli, Eleanor Barnes, Graham S. Cooke, Cori Campbell, Theresa Noble, David A. Smith, Steve Harris, Kinga A Várnai, Gail Roadknight, Hizni Salih, Ben Glampson, Stephanie Little, Dimitri Papadimitriou, Paul Klenerman, Luca Mercuri, Vince Taylor, Christopher R Jones, Hang Phan, Afzal Chaudhry, Josune Olza, Florina Borca, Luis Romão, Frazer Warricker, Louise English, David Ramlakhan, Monique I. Andersson, Salim I. Khakoo, Jane Collier, Philippa C. Matthews, Kerrie Woods, William Gelson, Tingyan Wang, Oliver Freeman, Jim Davies
Publikováno v:
Wellcome Open Research, Vol 7 (2023)
Background To determine the impact of the COVID-19 pandemic on the population with chronic Hepatitis B virus (HBV) infection under hospital follow-up in the UK, we quantified the coverage and frequency of measurements of biomarkers used for routine s
Externí odkaz:
https://doaj.org/article/c0516a624eaf4e1986582e7833115042
Autor:
Youngmin Lim, Bhuwan Nepal, David A. Smith, Shuang Wu, Abhishek Srivastava, Prabandha Nakarmi, Claudia Mewes, Zijian Jiang, Adbhut Gupta, Dwight D. Viehland, Christoph Klewe, Padraic Shafer, In Jun Park, Timothy Mabe, Vivek P. Amin, Jean J. Heremans, Tim Mewes, Satoru Emori
Publikováno v:
APL Materials, Vol 11, Iss 10, Pp 101121-101121-13 (2023)
An electrically conductive metal typically transmits or absorbs a spin current. Here, we report on evidence that interfacing two metal thin films can suppress spin transmission and absorption. We examine spin pumping in spin-source/spacer/spin-sink h
Externí odkaz:
https://doaj.org/article/2e940d138b6d4af2a5056ae66489086b
Autor:
Iain A. Gillespie, Eleanor Barnes, Ian C. K. Wong, Philippa C. Matthews, Graham S. Cooke, Craig Tipple, Robert C. Elston, Yunhao Liu, David A. Smith, Tingyan Wang, Jim Davies, Kinga A. Várnai, Oliver Freeman, Kenneth K. C. Man, Wallis C. Y. Lau, Ben Glampson, Xing Meng, Eleonora Morais, Sen Liu, Luca Mercuri, Naomi Boxall, Sarah Jenner, Stuart Kendrick, Jane Dong, Dickens Theodore
Publikováno v:
Infectious Diseases and Therapy, Vol 12, Iss 11, Pp 2533-2534 (2023)
Externí odkaz:
https://doaj.org/article/0b5399613fa9482087b0a6c07546eb13
Autor:
David A. Smith, Carlota Fernandez-Antunez, Andrea Magri, Rory Bowden, Nimisha Chaturvedi, Jacques Fellay, John McLauchlan, Graham R. Foster, William L. Irving, STOP-HCV Consortium, Peter Simmonds, Vincent Pedergnana, Santseharay Ramirez, Jens Bukh, Eleanor Barnes, M. Azim Ansari
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Sofosbuvir is a common therapy in hepatitis C virus infection, which targets the NS5B polymerase. Here, Smith et al. analyze the association between whole genome HCV polymorphisms and sofosbuvir treatment failure and identify three common polymorphis
Externí odkaz:
https://doaj.org/article/fba960aa3b6a4946a4842f08d7a24e6d
Autor:
Tingyan Wang, David A. Smith, Cori Campbell, Steve Harris, Hizni Salih, Kinga A. Várnai, Kerrie Woods, Theresa Noble, Oliver Freeman, Zuzana Moysova, Thomas Marjot, Gwilym J. Webb, Jim Davies, Eleanor Barnes, Philippa C. Matthews
Publikováno v:
Hepatology Communications, Vol 5, Iss 9, Pp 1586-1604 (2021)
The association of liver biochemistry with clinical outcomes of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection is currently unclear, and the utility of longitudinally measured liver biochemistry as prognostic markers for m
Externí odkaz:
https://doaj.org/article/2afadca7b5a847cd9da8894149e8af77
Autor:
Tingyan Wang, David A. Smith, Cori Campbell, Jolynne Mokaya, Oliver Freeman, Hizni Salih, Anna L. McNaughton, Sarah Cripps, Kinga A. Várnai, Theresa Noble, Kerrie Woods, Jane Collier, Katie Jeffery, Jim Davies, Eleanor Barnes, Philippa C. Matthews
Publikováno v:
BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-14 (2021)
Abstract Background Current clinical guidelines recommend treating chronic hepatitis B virus (HBV) infection in a minority of cases, but there are relatively scarce data on evolution or progression of liver inflammation and fibrosis in cases of chron
Externí odkaz:
https://doaj.org/article/d84c383aa57b426b92d6b24788bacfce
Autor:
Oscar C. W. Chen, Alexandria Colaco, Lianne C. Davis, Fedir N. Kiskin, Nicole Y. Farhat, Anneliese O. Speak, David A. Smith, Lauren Morris, Emily Eden, Patricia Tynan, Grant C. Churchill, Antony Galione, Forbes D. Porter, Frances M. Platt
Publikováno v:
JIMD Reports, Vol 56, Iss 1, Pp 46-57 (2020)
Abstract Niemann‐Pick disease type C (NPC) is a neurodegenerative lysosomal storage disorder caused by mutations in either NPC1 (95% of cases) or NPC2. Reduced late endosome/lysosome calcium (Ca2+) levels and the accumulation of unesterified choles
Externí odkaz:
https://doaj.org/article/0e1a6412d2a14de1a7841b940a26ea33
Autor:
Louise O. Downs, Sabeehah Vawda, Phillip Armand Bester, Katrina A. Lythgoe, Tingyan Wang, Anna L. McNaughton, David A. Smith, Tongai Maponga, Oliver Freeman, Kinga A. Várnai, Jim Davies, Kerrie Woods, Christophe Fraser, Eleanor Barnes, Dominique Goedhals, Philippa C. Matthews
Publikováno v:
Wellcome Open Research, Vol 5 (2020)
Hepatitis B virus (HBV) viral load (VL) is used as a biomarker to assess risk of disease progression, and to determine eligibility for treatment. While there is a well recognised association between VL and the expression of the viral e-antigen protei
Externí odkaz:
https://doaj.org/article/0fbaaa29dc1d4b77ad9dea0466d4f111
Autor:
Saroj Vadhan-Raj, Rafat Abonour, Jonathan W. Goldman, David A. Smith, Christopher A. Slapak, Robert L. Ilaria, Ramon V. Tiu, Xuejing Wang, Sophie Callies, Joanne Cox, Jay L. Tuttle, Yiu-Keung Lau, Eric J. Roeland
Publikováno v:
Journal of Hematology & Oncology, Vol 10, Iss 1, Pp 1-12 (2017)
Abstract Background Hepcidin plays a central role in iron homeostasis and erythropoiesis. Neutralizing hepcidin with a monoclonal antibody (mAb) may prevent ferroportin internalization, restore iron efflux from cells, and allow transferrin-mediated i
Externí odkaz:
https://doaj.org/article/d0975f366e274a1ea6ec2e25ee746386