Zobrazeno 1 - 10
of 94
pro vyhledávání: '"David A. Riddle"'
Autor:
Carlos L. Arteaga, Erik S. Knudsen, Wenyi Wei, Teresa C. Dugger, David A. Riddle, Michael J. Pishvaian, Paula R. Pohlmann, Melinda E. Sanders, Paula G. Ericsson, Violeta Sánchez, Mónica Valéria Estrada, Preston D. Moore, Agnieszka K. Witkiewicz, Katherine E. Hutchinson, Kyung-Min Lee, Luigi Formisano, Joshua A. Bauer, Neil E. Bhola, Valerie M. Jansen
Acquired resistance to cyclin-dependent kinases 4 and 6 (CDK4/6) small-molecule inhibitors in breast cancer arises through mechanisms that are yet uncharacterized. In this study, we used a kinome-wide siRNA screen to identify kinases that, when downr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::878135b809b1f085cc62987f886868e5
https://doi.org/10.1158/0008-5472.c.6509882.v1
https://doi.org/10.1158/0008-5472.c.6509882.v1
Autor:
Carlos L. Arteaga, Erik S. Knudsen, Wenyi Wei, Teresa C. Dugger, David A. Riddle, Michael J. Pishvaian, Paula R. Pohlmann, Melinda E. Sanders, Paula G. Ericsson, Violeta Sánchez, Mónica Valéria Estrada, Preston D. Moore, Agnieszka K. Witkiewicz, Katherine E. Hutchinson, Kyung-Min Lee, Luigi Formisano, Joshua A. Bauer, Neil E. Bhola, Valerie M. Jansen
Supplementary Figure S1. RNAi screen to identify kinases that sensitize cells to CDK4/6 inhibition. Supplementary Figure S2. Calculation of the sensitivity index (SI) value. Supplementary Figure S3. PDK1 and CDK4/6 inhibitors are synergistic against
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad87a39fc7665994129ea46a0e522f6a
https://doi.org/10.1158/0008-5472.22417598.v1
https://doi.org/10.1158/0008-5472.22417598.v1
Autor:
Carlos L. Arteaga, Erik S. Knudsen, Wenyi Wei, Teresa C. Dugger, David A. Riddle, Michael J. Pishvaian, Paula R. Pohlmann, Melinda E. Sanders, Paula G. Ericsson, Violeta Sánchez, Mónica Valéria Estrada, Preston D. Moore, Agnieszka K. Witkiewicz, Katherine E. Hutchinson, Kyung-Min Lee, Luigi Formisano, Joshua A. Bauer, Neil E. Bhola, Valerie M. Jansen
Supplementary Materials and Methods and Figure Legends for Supplementary Figures S1-6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2af58ae1fd4d3e24d6c5e617f0e03c98
https://doi.org/10.1158/0008-5472.22417595.v1
https://doi.org/10.1158/0008-5472.22417595.v1
Publikováno v:
How the COVID-19 Pandemic Transformed the Mental Health Landscape ISBN: 9781003352235
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::778d4dd50ea1acad63655b4d64885e26
https://doi.org/10.4324/9781003352235-17
https://doi.org/10.4324/9781003352235-17
Publikováno v:
The FASEB Journal. 35
Autor:
Amanda Javorina, Mark W Lisanby, Shana Huntsberger, Tim C Chao, Richard R Chapleau, Benjamin Connors, Clarise Starr, Kenney Reynolds, Christa Premo, Monica Christian, Juan J. Llibre Rodriguez, David S Riddle, Jennifer Meyer
The first case of non-travel related SARS-COV-2 was detected late February 2020 in California, however the delay of diagnostic testing and initial stringent testing criteria made it difficult to identify those who could have acquired it through commu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9871d8185e9769500fb912c81c9932ec
https://doi.org/10.1101/2021.02.18.21251368
https://doi.org/10.1101/2021.02.18.21251368
Publikováno v:
Med Sci Educ
A case-based laboratory event integrating neuroanatomy, neuroscience, and psychiatry was implemented into a pre-clerkship psychiatry-based course for second-year medical students. Learners rotating through lab stations to work on different cases to m
Focal Delivery of Neurotrophins into the Central Nervous System Using Fluorescent Latex Microspheres
Publikováno v:
BioTechniques, Vol 23, Iss 5, Pp 928-937 (1997)
A new technique for in vivo and in vitro delivery of neurotrophins is described. The method is based upon the ability of certain fluorescent latex microspheres to adsorb large quantities of neurotrophin and then release the factor for at least three
Externí odkaz:
https://doaj.org/article/31590919ec9d4322841669ef438b5281
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52728 (2012)
Radiation therapy has proven efficacy for treating brain tumors and metastases. Higher doses and larger treatment fields increase the probability of eliminating neoplasms and preventing reoccurrence, but dose and field are limited by damage to normal
Externí odkaz:
https://doaj.org/article/bff66d27e1c04b438741192f4e34e187
Autor:
Vincent A. Miller, Carlos L. Arteaga, Rebecca J. Nagy, Richard B. Lanman, Gregory Sliwoski, Jie He, Kyungmin Lee, David A Riddle, Jonathan H. Sheehan, Sarah Croessmann, Justin M. Balko, Jens Meiler, Ingrid A. Mayer, Lewis C. Cantley
Publikováno v:
Clinical Cancer Research. 24:1426-1435
Purpose: We describe herein a novel P447_L455 deletion in the C2 domain of PIK3CA in a patient with an ER+ breast cancer with an excellent response to the PI3Kα inhibitor alpelisib. Although PIK3CA deletions are relatively rare, a significant portio