Zobrazeno 1 - 3
of 3
pro vyhledávání: '"David A. Revelli"'
Autor:
Philip J. Kuehl, Christin M. Yingling, Devon Dubose, Michael Burke, David A. Revelli, Wenshu Chen, Wendy W. Dye, Steven A. Belinsky, Mathewos Tessema
Publikováno v:
Drug Delivery, Vol 28, Iss 1, Pp 767-775 (2021)
Topotecan is potent anti-cancer drug approved for various malignancies but hematopoietic toxicities undermine its wider application and use of its most effective dose. This study aims to improve these limitations through inhalation-delivery. The phar
Externí odkaz:
https://doaj.org/article/dc02d998734d408f9f931094d9d32474
Autor:
Philip J. Kuehl, Marcie J. Grimes, Devon Dubose, Michael Burke, David A. Revelli, Andrew P. Gigliotti, Steven A. Belinsky, Mathewos Tessema
Publikováno v:
Drug Delivery, Vol 25, Iss 1, Pp 1127-1136 (2018)
Intravenous (IV) topotecan is approved for the treatment of various malignancies including lung cancer but its clinical use is greatly undermined by severe hematopoietic toxicity. We hypothesized that inhalation delivery of topotecan would increase l
Externí odkaz:
https://doaj.org/article/3849580988424c208877112a36103a87
Publikováno v:
Frontiers in Cellular and Infection Microbiology
Frontiers in Cellular and Infection Microbiology, Vol 2 (2012)
Frontiers in Cellular and Infection Microbiology, Vol 2 (2012)
Pulmonary melioidosis, a disease manifestation caused by the bacterium Burkholderia pseudomallei, has been studied using aerosols or intranasal (IN) inoculation in small animal models. Both have inherent disadvantages which may not accurately model p