Zobrazeno 1 - 10
of 122
pro vyhledávání: '"David A. Petrone"'
Publikováno v:
Acta Crystallographica Section E, Vol 67, Iss 7, Pp o1848-o1848 (2011)
In the title molecule, C25H30O4, the napthalene ring system is slightly bowed, with a dihedral angle of 4.37 (13)° between the two benzene rings.
Externí odkaz:
https://doaj.org/article/08ccebb00a9f428b99629578a6820104
Autor:
Supratim Ghosh, Avtar Changotra, David A. Petrone, Mayuko Isomura, Erick M. Carreira, Raghavan B. Sunoj
Publikováno v:
Journal of the American Chemical Society. 145:2884-2900
Autor:
Emma K. Davison, David A. Petrone, Michael Meanwell, Matthew B. Nodwell, Steven M. Silverman, Louis-Charles Campeau, Robert Britton
Publikováno v:
Nature Protocols. 17:2008-2024
Autor:
Piers St. Onge, Zheng-Wang Qu, Stefan Grimme, Douglas W. Stephan, David A. Petrone, Linkun Miao, Kevin M. Szkop
Publikováno v:
Angewandte Chemie International Edition. 60:18547-18551
Primary acyl-phosphines are scarce in the literature. Here we show that the reaction of Ph3 GePCO with the ylide Ph3 PCH2 proceeds to give the species Ph3 PCHC(O)PH(GePh3 ) 1. Deprotonation of 1 with Na[N(SiMe3 )2 ] generates the salt [Na(THF)2 ][Ph3
Publikováno v:
Journal of the American Chemical Society. 143:3323-3329
Enantioselective bond formation between sterically hindered fragments to furnish acyclic products with vicinal quaternary centers is a formidable challenge. We report a solution that involves cocatalysis between a chiral Ir-(phosphoramidite,olefin) c
Autor:
Marko Nesic, David B. Ryffel, Jonathan Maturano, Michael Shevlin, Scott R. Pollack, Donald R. Gauthier, Pablo Trigo-Mouriño, Li-Kang Zhang, Danielle M. Schultz, Jamie M. McCabe Dunn, Louis-Charles Campeau, Niki R. Patel, David A. Petrone, David Sarlah
The total synthesis of darobactin A, a recently isolated antibiotic that selectively targets Gram-negative bacteria, has been accomplished in a convergent fashion with a longest linear sequence of 16 steps from ᴅ-Garner’s aldehyde and ʟ-serine.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85995d27bf0e6c17b4961bc72d2ca3c0
https://doi.org/10.26434/chemrxiv-2022-c4mz6
https://doi.org/10.26434/chemrxiv-2022-c4mz6
Autor:
Emma K, Davison, David A, Petrone, Michael, Meanwell, Matthew B, Nodwell, Steven M, Silverman, Louis-Charles, Campeau, Robert, Britton
Publikováno v:
Nature protocols. 17(9)
Nucleoside analogs are valuable commodities in the development of antisense oligonucleotides or as stand-alone antiviral and anticancer therapies. Syntheses of nucleoside analogs are typically challenged by a reliance on chiral pool starting material
Publikováno v:
Journal of the American Chemical Society. 141:4738-4748
The inherent difficulty in eliciting facial control over carbocations has limited their utility as intermediates in asymmetric catalysis. We have now shown that a docking strategy involving the reversible coordination of a substrate to a chiral trans
Autor:
David A. Petrone, Katherine I. Burton, José F. Rodríguez, Ivan Franzoni, Mark Lautens, Ina Scheipers
Publikováno v:
Organic Letters. 20:6915-6919
The use of ammonium halide salts as metal hydride precursors in a new Pd-catalyzed cycloisomerization of 1,6-diynes, which affords unexplored silylated 2-azafluorenes, is reported. This cascade process includes the addition of a Pd-hydride species to
Publikováno v:
Accounts of chemical research. 52(9)
The catalytic, asymmetric synthesis of complex molecules has been a core focus of our research program for some time because developments in the area can have an immediate impact on the identification of novel strategies for the synthesis of value-ad