Zobrazeno 1 - 10
of 666
pro vyhledávání: '"David A. Newell"'
Autor:
Ben C. Scheele, Matthijs Hollanders, Emily P. Hoffmann, David A. Newell, David B. Lindenmayer, Michael McFadden, Deon J. Gilbert, Laura F. Grogan
Publikováno v:
Conservation Science and Practice, Vol 3, Iss 11, Pp n/a-n/a (2021)
Abstract Emerging infectious diseases are an increasingly prominent threat to biodiversity. However, traditional methods in conservation generally have limited efficacy in the face of disease threats. Ironically, although unintentional human movement
Externí odkaz:
https://doaj.org/article/a224d09c4ad84009879af63d0f8e72e9
Autor:
Laura F. Grogan, Jacques Robert, Lee Berger, Lee F. Skerratt, Benjamin C. Scheele, J. Guy Castley, David A. Newell, Hamish I. McCallum
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The fungal skin disease, chytridiomycosis (caused by Batrachochytrium dendrobatidis and B. salamandrivorans), has caused amphibian declines and extinctions globally since its emergence. Characterizing the host immune response to chytridiomycosis has
Externí odkaz:
https://doaj.org/article/3da030eaed664deb8bf72a98a4fe9eeb
Autor:
Laura F. Grogan, Josephine E. Humphries, Jacques Robert, Chantal M. Lanctôt, Catherine J. Nock, David A. Newell, Hamish I. McCallum
Publikováno v:
Journal of Fungi, Vol 6, Iss 4, p 234 (2020)
Amphibians are currently the most threatened vertebrate class, with the disease chytridiomycosis being a major contributor to their global declines. Chytridiomycosis is a frequently fatal skin disease caused by the fungal pathogens Batrachochytrium d
Externí odkaz:
https://doaj.org/article/e5d462b597f34548a5ac6262a1b64b69
Publikováno v:
Future Internet, Vol 4, Iss 2, Pp 551-562 (2012)
The advent and adoption of Web 2.0 technologies offers a powerful approach to enhancing the capture of information in natural resource ecology, notably community knowledge of species distributions. Such information has previously been collected using
Externí odkaz:
https://doaj.org/article/92eae329f12a4f2a8f653a7853bcdfec
Autor:
Frank C. Seifert, Alireza R. Panna, I-Fan Hu, Lorenz H. Keck, Leon S. Chao, Shamith U. Payagala, Dean G. Jarrett, Chieh-I Liu, Dipanjan Saha, Randolph E. Elmquist, Stephan Schlamminger, Albert F. Rigosi, David B. Newell, Darine Haddad
Publikováno v:
Communications Physics, Vol 5, Iss 1, Pp 1-6 (2022)
The SI units, some of which were initially defined using physical objects, have come to rely on more stable and reproducible forms of measurement in order to improve accuracy. Here, the authors integrate a quantum Hall resistance array and programmab
Externí odkaz:
https://doaj.org/article/940bd52bf0eb44de800647e593ac2ea5
Publikováno v:
IEEE Open Journal of Instrumentation and Measurement, Vol 1, Pp 1-10 (2022)
The torsion pendulum at the heart of the apparatus to measure the gravitational constant, $G$ at the Bureau International des Poids et Mesures (BIPM) is used to measure the gravitational torque between source and test-mass assemblies with two methods
Externí odkaz:
https://doaj.org/article/1a5ef53e23ad4bd5937fd2b8872a4b97
Autor:
Nicola J. Curtin, Graeme C.M. Smith, David R. Newell, Niall M.B. Martin, Pia Thommes, Andrew Slade, Keith Menear, Roger J. Griffin, Liam Cornell, Julia Bardos, Jody Barbeau, Michele Tavecchio, Celine Cano, Caroline J. Richardson, Helen Jenkins, Yan Zhao, Michael A. Batey, Joanne M. Munck
DNA double-strand breaks (DSB) are the most cytotoxic lesions induced by topoisomerase II poisons. Nonhomologous end joining (NHEJ) is a major pathway for DSB repair and requires DNA-dependent protein kinase (DNA-PK) activity. DNA-PK catalytic subuni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33c9f0d0e3e98828130b4f41f16e3e80
https://doi.org/10.1158/1535-7163.c.6535653.v1
https://doi.org/10.1158/1535-7163.c.6535653.v1
Autor:
Matthew V. Lorenzi, Sylvie Laquerre, Patrick Angibaud, Christopher Moy, Jayaprakash D. Karkera, Suso J. Platero, Jennifer Yang, Liang Xie, Na Cheng, David R. Newell, Neil T. Thompson, George Ward, Ron Gilissen, Christopher W. Murray, Martin Page, Gordon Saxty, Matthew Squires, David C. Rees, Eddy Freyne, Peter King, Kelly Van De Ven, Caroline Paulussen, Tinne Verhulst, Desiree De Lange, Jorge Vialard, Laurence Mevellec, Eleonora Jovcheva, Timothy P.S. Perera
A) Structure of JNJ-42541707, a structurally related compound to JNJ-42756493. B) 72h growth inhibition (IC50) of JNJ-42541707 against 236 cancer cell lines from multiple origins color coded based on FGFR1,2,4 mRNA overexpression and FGFR WT.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::014876daf0ea3141cec8e46d4cd3afe8
https://doi.org/10.1158/1535-7163.22503741
https://doi.org/10.1158/1535-7163.22503741
Autor:
Neil T. Thompson, David R. Newell, Christopher Murray, Julie Irving, John Lyons, Eddy Freyne, Edward J. Lewis, Jose Cosme, Andrew Pike, Brent L. Graham, Lindsay A. Devine, Susanne Bethell, Abarna Thiru, Ruth Feltell, Darcey Miller, Maria Carr, Sharna Rich, Michael A. Batey, Christopher Hamlett, Michael Reader, Martyn Frederickson, Alistair O'Brien, Emma Vickerstaffe, Rajdeep K. Benning, Andrew Madin, Charlotte Griffiths Jones, Douglas Ross, Lynsey Fazal, Tim Perera, Patrick Angibaud, Peter King, Anne Cleasby, Valerio Berdini, Gordan Saxty, George Ward, Matthew Squires
We describe here the identification and characterization of 2 novel inhibitors of the fibroblast growth factor receptor (FGFR) family of receptor tyrosine kinases. The compounds exhibit selective inhibition of FGFR over the closely related VEGFR2 rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::605eebdec9c9d2137ffcbba68a3b82cd
https://doi.org/10.1158/1535-7163.c.6535227
https://doi.org/10.1158/1535-7163.c.6535227
Autor:
Matthew V. Lorenzi, Sylvie Laquerre, Patrick Angibaud, Christopher Moy, Jayaprakash D. Karkera, Suso J. Platero, Jennifer Yang, Liang Xie, Na Cheng, David R. Newell, Neil T. Thompson, George Ward, Ron Gilissen, Christopher W. Murray, Martin Page, Gordon Saxty, Matthew Squires, David C. Rees, Eddy Freyne, Peter King, Kelly Van De Ven, Caroline Paulussen, Tinne Verhulst, Desiree De Lange, Jorge Vialard, Laurence Mevellec, Eleonora Jovcheva, Timothy P.S. Perera
In vitro kinase inhibition by DiscoverX KinomeScan assay. For details see (19)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::707b5abacc5ec387fe47990836d03d73
https://doi.org/10.1158/1535-7163.22503738
https://doi.org/10.1158/1535-7163.22503738