Zobrazeno 1 - 9
of 9
pro vyhledávání: '"David A. Muthard"'
Autor:
Thomas N. Salzmann, Jean S. Kahan, Frank P. DiNinno, Joann Huber, David A. Muthard, Helmut Kropp
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 5:945-948
The discovery and synthesis of the arylcarbapenem 2b possessing potent activity against highly resistant strains of methicillin resistant staphylococci are dislosed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f5a88691499395fd1cb8d0b4d959eb2
https://doi.org/10.1016/0960-894x(95)00149-n
https://doi.org/10.1016/0960-894x(95)00149-n
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 3:2187-2192
The synthesis and in vitro antibacterial activity of 2-phenylcarbapenems bearing a spacer linked heteroaromatic or heterocyclic quaternized moiety are discussed. In general, this class of antibiotics was found to possess antibacterial activity superi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5af88b85ea0829cd670b34d3cfd914c3
https://doi.org/10.1016/s0960-894x(01)80923-9
https://doi.org/10.1016/s0960-894x(01)80923-9
Autor:
Thomas N. Salzmann, Frank P. DiNinno, Helmut Kropp, Joann Huber, David A. Muthard, Jean S. Kahan
Publikováno v:
ChemInform. 26
The discovery and synthesis of the arylcarbapenem 2b possessing potent activity against highly resistant strains of methicillin resistant staphylococci are dislosed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3b925c1defd4c6a99d468b1d05c1b1b
https://doi.org/10.1002/chin.199537276
https://doi.org/10.1002/chin.199537276
Autor:
Cynthia Jaworsky, Jeffrey J. Herrmann, Mark L. Greenlee, Frank P. DiNinno, Thomas N. Salzmann, David A. Muthard
Publikováno v:
ChemInform. 31
A regioisomeric set of 2-naphthylcarbapenems featuring cationic substituents was synthesized. Optimal placement of the cationic group was found to markedly improve activity against methicillin-resistant staphylococci while maintaining a good spectrum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aae275d8823d694067606b388e109b55
https://doi.org/10.1002/chin.200007211
https://doi.org/10.1002/chin.200007211
Autor:
Thomas N. Salzmann, Jeffrey J. Herrmann, Mark L. Greenlee, David A. Muthard, Frank P. DiNinno, Cynthia Jaworsky
Publikováno v:
Bioorganicmedicinal chemistry letters. 9(19)
A regioisomeric set of 2-naphthylcarbapenems featuring cationic substituents was synthesized. Optimal placement of the cationic group was found to markedly improve activity against methicillin-resistant staphylococci while maintaining a good spectrum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf5031b0ae3de3870aa0cbb7b0d0a9b1
https://pubmed.ncbi.nlm.nih.gov/10522713
https://pubmed.ncbi.nlm.nih.gov/10522713
Publikováno v:
Tetrahedron Letters. 23:3535-3538
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f03e66554551c07bd020f581f8e166a
https://doi.org/10.1016/s0040-4039(00)87662-5
https://doi.org/10.1016/s0040-4039(00)87662-5
Autor:
Frank P. DiNinno, B.G. Christensen, Robert R. Wilkening, William J. Leanza, Ronald W. Ratcliffe, David A. Muthard, Kenneth J. Wildonger
Publikováno v:
Tetrahedron. 39:2505-2513
Allyl and p -nitrobenzyl (5R, 6S)-6-[(R)-1-(t-butyldimethylsilyloxy)ethyl]-2-thioxopenam-3-carboxylates ( 19 ) were synthesized by base mediated cyclization of the corresponding 1-carboxylmethyl-4-phenoxy (thiocarbonyl)thio-2-azetidinones ( 16 ). The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b30e7706a7f22c5ad037ccdb3cc1ff26
https://doi.org/10.1016/s0040-4020(01)92144-1
https://doi.org/10.1016/s0040-4020(01)92144-1
Publikováno v:
Journal of the American Chemical Society. 102:7365-7367
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c17bf12b7e9f985742c2284ead1965c5
https://doi.org/10.1021/ja00544a037
https://doi.org/10.1021/ja00544a037
Publikováno v:
Journal of the American Chemical Society. 101:2784-2785
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::213b2f8a3c3b757ea6ffb3e44cac7bb3
https://doi.org/10.1021/ja00504a074
https://doi.org/10.1021/ja00504a074