Zobrazeno 1 - 10
of 50
pro vyhledávání: '"David A. Lammas"'
The pathogenic yeast Cryptococcus neoformans and C. gattii commonly cause severe infections of the central nervous system in patients with impaired immunity but also increasingly in immunocompetent individuals. Cryptococcus is phagocytosed by macroph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a73b28e4367664e5d4d5e33e2e0d275
https://europepmc.org/articles/PMC5116742/
https://europepmc.org/articles/PMC5116742/
Publikováno v:
Clinics in dermatology, 34(1), 82-95. Elsevier Inc.
Advances concerning the hosts' immune response to Mycobacterium leprae infection have focused on elucidating the immune pathomechanisms involved, with the hope that predictive diagnostic and prognostic parameters (biomarkers) for field use would emer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fc3e67c10b9eb72ac94d92f4fed0151
https://pubmed.ncbi.nlm.nih.gov/26773628
https://pubmed.ncbi.nlm.nih.gov/26773628
Autor:
Manuela Mura, David A. Lammas, Louisa E. Jeffery, Martin Hewison, Lucy S. K. Walker, Omar S. Qureshi, Yong Zheng, David M. Sansom, Karim Raza, Fiona Burke
Publikováno v:
The Journal of Immunology. 183:5458-5467
The active form of vitamin D, 1,25-dihydroxyvitamin D3 (1,25(OH)2D3), has potent immunomodulatory properties that have promoted its potential use in the prevention and treatment of infectious disease and autoimmune conditions. A variety of immune cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b72af133e318188eb306b5c97b0df6c8
https://doi.org/10.4049/jimmunol.0803217
https://doi.org/10.4049/jimmunol.0803217
Autor:
David M Isherwood, J Brian S Coulter, Laurance J Abernethy, David A. Lammas, Dinakantha S. Kumararatne, Connor L Mallucci, Maria I Romano, Richard Baretto
Publikováno v:
The Lancet Infectious Diseases. 7:225-232
A 12-year-old girl with protracted tuberculous meningitis received standard chemotherapy and dexamethasone and had a progressive cerebrospinal fluid neutrophilia, raised protein and depressed glucose levels. Her temperature was raised for 5 months un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57aa10e55be1009ac1f785903af759b2
https://doi.org/10.1016/s1473-3099(07)70054-3
https://doi.org/10.1016/s1473-3099(07)70054-3
Publikováno v:
Current Biology. 16:2156-2160
Summary Phagocytic cells, such as neutrophils and macrophages, perform a critical role in protecting organisms from infection by engulfing and destroying invading microbes [1]. Although some bacteria and fungi have evolved strategies to survive withi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f74ab8401e853221fb12096e21b50c5
https://doi.org/10.1016/j.cub.2006.09.032
https://doi.org/10.1016/j.cub.2006.09.032
Autor:
Todd L. Lowary, Gurdyal S. Besra, Hashem Taha, Daniel Q. Sun, David A. Lammas, Joanne E. Croudace, Gladys C. Completo, Maju Joe
Publikováno v:
Journal of the American Chemical Society. 128:5059-5072
Mycobacteria produce a cell-surface glycoconjugate, lipoarabinomannan (LAM), which has been shown to be a potent modulator of the immune response that arises from infection by these organisms. Recently, LAM from the human pathogens Mycobacterium tube
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28474b44f4051be923e8cd502a1f1964
https://doi.org/10.1021/ja057373q
https://doi.org/10.1021/ja057373q
Autor:
Joachim Roesler, Dinakantha S. Kumararatne, David A. Lammas, Melanie J. Newport, Richard Baretto, Sergio D. Rosenzweig, Steven M. Holland, Susan E. Dorman, Capucine Picard, Michael Levin, Klaus Heyne, Jaap T. van Dissel, Jean-Laurent Casanova
Publikováno v:
The Lancet. 364:2113-2121
BACKGROUND Interferon gamma receptor 1 (IFNgammaR1) deficiency is a primary immunodeficiency with allelic dominant and recessive mutations characterised clinically by severe infections with mycobacteria. We aimed to compare the clinical features of r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6d6969957b64460126cb305580b75fd
https://doi.org/10.1016/s0140-6736(04)17552-1
https://doi.org/10.1016/s0140-6736(04)17552-1
Autor:
Adam F. Cunningham, Paul R. Wheeler, Christopher W. Wharton, Claire L. Spreadbury, David A. Lammas, Peter R. Ashton, Rachel Craddock
Publikováno v:
FEMS Microbiology Letters. 235:191-198
Many cases of tuberculosis result from reactivation of previously acquired latent infections. Models to study such persister forms often involve gradual depletion of oxygen during culture as poor aeration is a characteristic of non-progressive TB gra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90de65ffc8dd435e788e9135cb31ea58
https://doi.org/10.1111/j.1574-6968.2004.tb09586.x
https://doi.org/10.1111/j.1574-6968.2004.tb09586.x
Publikováno v:
Journal of Helminthology. 77:133-146
T helper cell (Th1 and Th2) associated responses were examined following a primary infection with the gastrointestinal nematode Heligmosomoides polygyrus in five inbred strains of mice with different resistance phenotypes. Levels of (i) mast cell pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a023df7fd6e6fd7aee1975ecd8d018f2
https://doi.org/10.1079/joh2003173
https://doi.org/10.1079/joh2003173
Autor:
Suliman Al-Jumaah, Frédéric Altare, David Nadal, Vas Novelli, Mohammad S. Ehlayel, Martin Brezina, Stéphanie Dupuis, Claire Fieschi, Laurent Abel, Jacinta Bustamante, Guzide Aksu, Necil Kutukculer, Jean Louis Virelizier, Isabel Caragol, Graham Davies, Walther H. Haas, Claire-Anne Siegrist, Joachim Freihorst, Olle Jeppsson, Emilie Catherinot, Jacob Levy, Phil Wood, Dewton de Moraes Vasconcelos, Alberto José da Silva Duarte, Renate Blütters-Sawatzki, Françoise Le Deist, Aileen M. Cleary, David A. Lammas, Jacqueline Feinberg, Jutta Bernhöft, Darko Richter, Klara Frecerova, Alain Fischer, Hartmut Koch, Jean-Laurent Casanova, Andrea M. Enright, Richard Baretto, Christiane Vermylen, David Tuerlinckx, Dinakantha S. Kumararatne, Miquel Raspall, Sami Al-Hajjar, Carlos Rodríguez-Gallego, Adrien Breiman, Samer Kayal
Publikováno v:
The Journal of Experimental Medicine
The clinical phenotype of interleukin 12 receptor β1 chain (IL-12Rβ1) deficiency and the function of human IL-12 in host defense remain largely unknown, due to the small number of patients reported. We now report 41 patients with complete IL-12Rβ1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f015769c6bcc156a9a0c93cd904c4d7
http://europepmc.org/articles/PMC2193866
http://europepmc.org/articles/PMC2193866