Zobrazeno 1 - 10 of 173 pro vyhledávání: '"David A. Lai"'
1
Development of a serum miRNA panel for detection of early stage non-small cell lung cancer
Autor: Jiaoyue Jin, Lihan Zhou, Fanrong Zhang, Chen Zhu, Xiaodan Pan, Baofu Chen, Dan Su, Lisha Ying, Kaiyan Chen, David T. Lai, Yimin Zhang, Rob M. van Dam, Herbert Yu, Kee Seng Chia, Junzhou Wu, John Kit Chung Tam, Heng-Phon Too, Chenyang Xu, Minran Huang, Ruiyang Zou, Nan Zhang, Aifen Lin, Lingbin Du, Weihui Zheng, Yingxue Wu, Lei Shi, Weimin Mao
Publikováno v: Proc Natl Acad Sci U S A
Minimally invasive testing for early detection of lung cancer to improve patient survival is a major unmet clinical need. This study aimed to develop and validate a serum multi-microRNA (multimiR) panel as a minimally invasive test for early detectio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3db0915ff0e91275ff0ff16569e132f2
https://doi.org/10.1073/pnas.2006212117
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2
Efficient Neighborhood Evaluations for the Vehicle Routing Problem with Multiple Time Windows
Autor: Wout Dullaert, David S.W. Lai, Daniele Vigo, Maaike Hoogeboom
Publikováno v: Transportation Science, 54(2), 400-416. INFORMS Inst.for Operations Res.and the Management Sciences
Hoogeboom, M, Dullaert, W, Lai, D & Vigoa, D 2020, ' Efficient neighborhood evaluations for the vehicle routing problem with multiple time windows ', Transportation Science, vol. 54, no. 2, pp. 400-416 . https://doi.org/10.1287/trsc.2019.0912
In the vehicle routing problem with multiple time windows (VRPMTW), a single time window must be selected for each customer from the multiple time windows provided. Compared with classical vehicle routing problems with only a single time window per c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2dbc2418355fa6b979ff2b6fbac111c
https://doi.org/10.1287/trsc.2019.0912
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3
Facilitators and Barriers to Using Virtual Reality and its Impact on Social Engagement in Aged Care Settings: A Scoping Review
Autor: Lillian Hung, Jim Mann, Christine Wallsworth, Mona Upreti, Winnie Kan, Alisha Temirova, Karen Lok Yi Wong, Haopu Ren, Flora To-Miles, Joey Wong, Caitlin Lee, David Kar Lai So, Sonia Hardern
Publikováno v: Gerontology and Geriatric Medicine. 9:233372142311663
Aim: This scoping review aims to identify the facilitators and barriers to the implementation of VR technology in the aged-care setting. Background: Virtual reality (VR) offers the potential to reduce social isolation and loneliness through increased
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::db1d537e8910ddb3ab47eb5ba1c2b5b1
https://doi.org/10.1177/23337214231166355
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4
An exact algorithm for a rich vehicle routing problem with private fleet and common carrier
Autor: Said Dabia, Daniele Vigo, David S.W. Lai
Publikováno v: Transportation Science, 53(4), 986-1000. INFORMS Inst.for Operations Res.and the Management Sciences
Dabia, S, Lai, D & Vigo, D 2019, ' An exact algorithm for a rich vehicle routing problem with private fleet and common carrier ', Transportation Science, vol. 53, no. 4, pp. 986-1000 . https://doi.org/10.1287/trsc.2018.0852
The vehicle routing problem with private fleet and common carrier (VRPPC) is a generalization of the classical vehicle routing problem in which the owner of a private fleet can either visit a customer with one of the owner’s vehicles or assign the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6edce269be38b7562aa508455c07d5ea
https://research.vu.nl/en/publications/a0c2ea4b-d532-4433-861e-a35fcea3874a
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5
Extracellular Signal-Regulated Kinase (ERK) Inhibitors in Oncology Clinical Trials
Autor: David K Lai, Gerald S Falchook, Haelee M Chin
Publikováno v: Journal of Immunotherapy and Precision Oncology. 2:10-16
The mitogen-activated protein kinase (MAPK) pathway consists of the series of protein kinases RAS-RAF-MEK-Extracellular signal-regulated kinase (ERK), and its function is important to cell proliferation, differentiation, motility, and survival. Certa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ae793f1dc01680d8518c8c1975f2c2de
https://doi.org/10.4103/jipo.jipo_17_18
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6
A graph-based formulation for the shift rostering problem
Autor: Wout Dullaert, Janny M. Y. Leung, David S.W. Lai, Inês Marques
Publikováno v: Lai, D, Leung, J M Y, Dullaert, W & Marques, I 2020, ' A graph-based formulation for the shift rostering problem ', European Journal of Operational Research, vol. 284, no. 1, pp. 285-300 . https://doi.org/10.1016/j.ejor.2019.12.019
European Journal of Operational Research, 284(1), 285-300. Elsevier
This paper investigates a shift rostering problem – the assignment of staff to shifts over a planning horizon such that work rules are observed. Traditional integer-programming models are not able to solve shift rostering problems effectively for l
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f01d1a5f310bc4901239fdff9c441b7
https://research.vu.nl/en/publications/484f8ff6-5640-4f4d-918a-6d4d435ee6d8
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7
Measurement-based optimization and analysis of α-IGZO/Ag/α-IGZO transparent conducting electrodes fabricated using DC magnetron sputter deposition
Autor: Kuan W.A. Chee, Fanping Meng, David C. Lai, Feng Huang
Publikováno v: Ceramics International. 44:20939-20946
Transparent conducting electrodes have been systematically developed for optoelectronic devices and applications in industry through materials exploration and manufacturing process optimization. The nanostructural, optical and electrical properties w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c8d483d7f57953833b32191aab10caa1
https://doi.org/10.1016/j.ceramint.2018.06.277
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8
Point load strength index of granitic irregular lumps: Size correction and correlation with uniaxial compressive strength
Autor: Jianhua Yin, David T.W. Lai, Guang-Si Zhao, Robina H.C. Wong, Kam Tim Chau
Publikováno v: Tunnelling and Underground Space Technology. 70:388-399
The Uniaxial Compressive Strength (UCS) of rock cores is a key parameter for design analysis of rock engineering projects such as rock tunnels and piles in rockets. Diametral and axial point load tests on cylinder cores have been used to obtain Point
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c3335703a7d38ce06bb1744426c6ff0c
https://doi.org/10.1016/j.tust.2017.09.011
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9
Real-time rescheduling and disruption management for public transit
Autor: Janny M. Y. Leung, David S.W. Lai
Publikováno v: Transportmetrica. B : Transport Dynamics, 6(1), 1-17. Taylor& Francis
Lai, D S W & Leung, J M Y 2017, ' Real-time rescheduling and disruption management for public transit ', Transportmetrica. B : Transport Dynamics, vol. 6, no. 1, pp. 1-17 . https://doi.org/10.1080/21680566.2017.1358678
This research is motivated by the operations of a public transit company in Hong Kong. We investigate how real-time information can be utilized in combination with historical data to improve routing and scheduling decisions practically. A dynamic int
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bc830a1df81b6e8afe43c027987b351
https://research.vu.nl/en/publications/5bc3f161-4be6-4c1e-8df0-4223560c80c0
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