Zobrazeno 1 - 10
of 2 402
pro vyhledávání: '"David A. James"'
Publikováno v:
Frontiers in Clinical Diabetes and Healthcare, Vol 4 (2023)
IntroductionContinuous glucose monitoring (CGM) devices capture longitudinal data on interstitial glucose levels and are increasingly used to show the dynamics of diabetes metabolism. Given the complexity of CGM data, it is crucial to extract importa
Externí odkaz:
https://doaj.org/article/0b9d0c6469524d3d96058b394533bb20
Autor:
Philip Mease, Désirée van der Heijde, Bruce Kirkham, Georg Schett, Ana-Maria Orbai, Christopher Ritchlin, Joseph F. Merola, Luminita Pricop, David A. James, Xuan Zhu, Gregory Ligozio
Publikováno v:
Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-11 (2022)
Abstract Background Psoriatic arthritis (PsA) patient data from two phase 3 secukinumab trials (FUTURE 1, 5) were analysed to quantify the prevalence and extent of pre-existing radiographic damage (RD) at baseline; investigate the association of RD w
Externí odkaz:
https://doaj.org/article/88cfee0faae741c196f42420661bb5fc
Autor:
Jones, Joel W. *, Baumanis, Maraya M. *, Perryman, Mollie *, Sykes, Kevin J. *, Villwock, Mark R. *, Cabrera-Muffly, Cristina, Dowdall, Jayme, David Garnett, James *, Kraft, Shannon *
Publikováno v:
In Journal of Voice September 2021 35(5):772-778
Autor:
Martin J. Nicklin, David C. James, Domen Zafred, Jon R. Sayers, Goura Kudesia, Sarah L. Rowland-Jones, Paul J. Collini, Thushan I. de Silva, Thomas C. Darton, Hayley Colton, Hailey Hornsby, David Hodgson, Adam Kucharski, Joanne Mckenzie, Rebecca Brown, Cameron James, Kirsty L. Bradley, Sarah Birch, Benjamin B. Lindsey, Steven Wood, Louise Marsh, Gary Dickson, Martin Bayley
Publikováno v:
Wellcome Open Research, Vol 6 (2022)
Background: We aimed to measure SARS-CoV-2 seroprevalence in a cohort of healthcare workers (HCWs) during the first UK wave of the COVID-19 pandemic, explore risk factors associated with infection, and investigate the impact of antibody titres on ass
Externí odkaz:
https://doaj.org/article/63bb6e2e54a84a8dbb5b68e28523e2fe
Autor:
Martin J. Nicklin, David C. James, Domen Zafred, Jon R. Sayers, Goura Kudesia, Sarah L. Rowland-Jones, Paul J. Collini, Thushan I. de Silva, Thomas C. Darton, Hayley Colton, Hailey Hornsby, David Hodgson, Adam Kucharski, Joanne Mckenzie, Rebecca Brown, Cameron James, Kirsty L. Bradley, Sarah Birch, Benjamin B. Lindsey, Steven Wood, Louise Marsh, Gary Dickson, Martin Bayley
Publikováno v:
Wellcome Open Research, Vol 6 (2022)
Background: We aimed to measure SARS-CoV-2 seroprevalence in a cohort of healthcare workers (HCWs) during the first UK wave of the COVID-19 pandemic, explore risk factors associated with infection, and investigate the impact of antibody titres on ass
Externí odkaz:
https://doaj.org/article/604733d0d16a4d30ad7609f3c098ad70
Autor:
Enheng Wang, Richard M. Cruse, Bharat Sharma‐Acharya, Daryl E. Herzmann, Brian K. Gelder, David E. James, Dennis C. Flanagan, Humberto Blanco‐Canqui, Robert B. Mitchell, David A. Laird
Publikováno v:
GCB Bioenergy, Vol 12, Iss 11, Pp 955-967 (2020)
Abstract A strong need exists for tools to assess the efficacy of conservation practices across large regions supporting informed policy decisions that may lead to better soil and water conservation while optimizing agricultural production options. P
Externí odkaz:
https://doaj.org/article/8a96a9ec8c384f26a0188ac5b02ca37c
Autor:
Alison L Kearney, Dougall M Norris, Milad Ghomlaghi, Martin Kin Lok Wong, Sean J Humphrey, Luke Carroll, Guang Yang, Kristen C Cooke, Pengyi Yang, Thomas A Geddes, Sungyoung Shin, Daniel J Fazakerley, Lan K Nguyen, David E James, James G Burchfield
Publikováno v:
eLife, Vol 10 (2021)
The phosphoinositide 3-kinase (PI3K)-Akt network is tightly controlled by feedback mechanisms that regulate signal flow and ensure signal fidelity. A rapid overshoot in insulin-stimulated recruitment of Akt to the plasma membrane has previously been
Externí odkaz:
https://doaj.org/article/95b5ee5592d94a12a25916f631425d1d
Autor:
David W. James, Marcos Quintela, Lisa Lucini, Noor K. Alkafri, Gareth D. Healey, Kinza Younas, Adnan Bunkheila, Lavinia Margarit, Lewis W. Francis, Deyarina Gonzalez, 1 and R. Steven Conlan
Publikováno v:
Frontiers in Endocrinology; 2024, p1-13, 13p
Autor:
Lewin Small, Amanda E. Brandon, Benjamin L. Parker, Vinita Deshpande, Azrah F. Samsudeen, Greg M. Kowalski, Jane Reznick, Donna L. Wilks, Elaine Preston, Clinton R. Bruce, David E. James, Nigel Turner, Gregory J. Cooney
Publikováno v:
Molecular Metabolism, Vol 25, Iss , Pp 107-118 (2019)
Objective: Energy metabolism and insulin action follow a diurnal rhythm. It is therefore important that investigations into dysregulation of these pathways are relevant to the physiology of this diurnal rhythm. Methods: We examined glucose uptake, ma
Externí odkaz:
https://doaj.org/article/db9fca57c93a4a79959a2db147f25fc7
Autor:
Jacqueline Stöckli, Armella Zadoorian, Kristen C. Cooke, Vinita Deshpande, Belinda Yau, Gaia Herrmann, Melkam A. Kebede, Sean J. Humphrey, David E. James
Publikováno v:
Molecular Metabolism, Vol 25, Iss , Pp 83-94 (2019)
Objective: Insulin suppresses adipose tissue lipolysis after a meal, playing a key role in metabolic homeostasis. This is mediated via the kinase Akt and its substrate phosphodiesterase 3B (PDE3B). Once phosphorylated and activated, PDE3B hydrolyses
Externí odkaz:
https://doaj.org/article/89f28921dd844bddadf5ec401d3824cf