Zobrazeno 1 - 10
of 206
pro vyhledávání: '"David A. Hopwood"'
Autor:
David A. Hopwood
Publikováno v:
mBio, Vol 4, Iss 5 (2013)
ABSTRACT The genomes of actinomycetes contain numerous gene clusters potentially able to encode the production of many antibiotics and other specialized metabolites that are not expressed during growth under typical laboratory conditions. Undoubtedly
Externí odkaz:
https://doaj.org/article/e42993bba90845b78e5313560046070e
Autor:
David A. Hopwood
This is an insiders account of 50 years of genetic studies of the soil-inhabiting microbes that produce most of the antibiotics used to treat infections, as well as anti-cancer, anti-parasitic and immunosuppressant drugs. The book begins by describin
Autor:
David A. Hopwood, Keith F. Chater
Publikováno v:
Genetics and Breeding of Industrial Microorganisms ISBN: 9781351072243
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19aed97936140007b37b138ef1f930b9
https://doi.org/10.1201/9781351072243-2
https://doi.org/10.1201/9781351072243-2
Autor:
David A. Hopwood
Publikováno v:
Heredity (Edinb)
Sixty years ago, the actinomycetes, which include members of the genus Streptomyces, with their bacterial cellular dimensions but a mycelial growth habit like fungi, were generally regarded as a possible intermediate group, and virtually nothing was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69ee0adbb432a50f975c1bd5a3bfcb5f
https://pubmed.ncbi.nlm.nih.gov/31189905
https://pubmed.ncbi.nlm.nih.gov/31189905
Autor:
M. Barış Uzel, Catherine P. Foster, Reilly Jensen, Kathleen Nicoll, Kristen Butler, Jason R. Kennedy, Alexia Smith, Philip J. Graham, Bradley J. Parker, Elizabeth Healey, David E. Hopwood, Marie Hopwood
Publikováno v:
Anatolica. 35:85-152
Introduction During the summer of 2005 members of the Upper Tigris Archaeological Research Project (UTARP) undertook a sixth season of archaeological field work at the site of Kenan Tepe in the Upper Tigris River region of southeastern Turkey. This r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4796eeb6fcf86d8dc3434b6c83fc2bc
https://doi.org/10.2143/ana.35.0.2038073
https://doi.org/10.2143/ana.35.0.2038073
Autor:
Fritz Titgemeyer, Gilles P. van Wezel, Andreas W. Thomae, Suzanne Mulder, David A. Hopwood, Sharief Barends, Sébastien Rigali
Publikováno v:
EMBO reports. 9:670-675
Members of the soil‐dwelling prokaryotic genus Streptomyces produce many secondary metabolites, including antibiotics and anti‐tumour agents. Their formation is coupled with the onset of development, which is triggered by the nutrient status of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60f2eac0a64bd8a3566a2c3c08413265
https://doi.org/10.1038/embor.2008.83
https://doi.org/10.1038/embor.2008.83
Autor:
David A Hopwood
Publikováno v:
Journal of industrial microbiologybiotechnology. 43(2-3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a24363ec3a4f8901ebbd7207227df2d
https://pubmed.ncbi.nlm.nih.gov/26186906
https://pubmed.ncbi.nlm.nih.gov/26186906
Autor:
Eva Ilkoy, Istvan Kurucz, Gabor Ambrus, Attila Andor, Ferenc Jeanplong, Antonia Jekkel, Attila Kónya, David A. Hopwood
Publikováno v:
Applied and Environmental Microbiology. 72:6554-6559
Since 1980, synthesis of most steroid drugs (androgens, anabolic steroids, estrogens, and corticosteroids) has been based on microbial transformation of sitosterol (14). The important starting materials for these industrial syntheses, 4-androstene-3,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d31e2904074c85c17af3f1a9f5e9b7f8
https://doi.org/10.1128/aem.00941-06
https://doi.org/10.1128/aem.00941-06
Autor:
Kedar G. Patel, Ralph Reid, Sunil S. Chandran, Daniel V. Santi, Hugo G. Menzella, Sarah J. Reisinger, David A. Hopwood, John R. Carney
Publikováno v:
Nature Biotechnology. 23:1171-1176
Type I polyketide synthase (PKS) genes consist of modules approximately 3-6 kb long, which encode the structures of 2-carbon units in polyketide products. Alteration or replacement of individual PKS modules can lead to the biosynthesis of 'unnatural'
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::667753fe15a2afd52c0463886e0abaea
https://doi.org/10.1038/nbt1128
https://doi.org/10.1038/nbt1128
Autor:
Kevin I. Booker‐Milburn, Rebecca Gillan, Meriel Kimberley, Takaaki Taguchi, Koji Ichinose, G. Richard Stephenson, Yutaka Ebizuka, David A. Hopwood
Publikováno v:
Angewandte Chemie. 117:1145-1149
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3c911d97ba0e349bde2d49b620876fa
https://doi.org/10.1002/ange.200462076
https://doi.org/10.1002/ange.200462076