Zobrazeno 1 - 10
of 11
pro vyhledávání: '"David A. Hoagey"'
Publikováno v:
Human Brain Mapping
Cortical atrophy and degraded axonal health have been shown to coincide during normal aging; however, few studies have examined these measures together. To lend insight into both the regional specificity and the relative timecourse of structural degr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf0c899930e31eccdb83605f1afd955b
https://doi.org/10.1002/hbm.24774
https://doi.org/10.1002/hbm.24774
Autor:
Patricio M. Viera Perez, Karen M. Rodrigue, Christina E. Webb, Chen Gonen, Kristen M. Kennedy, David A. Hoagey
Healthy aging is accompanied by degraded white matter connectivity, which has been suggested to contribute to cognitive dysfunction observed in aging, especially in relation to fluid measures of cognition. Prior research linking white matter microstr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00d1b58233335cf21a812ed8bd37d70d
https://doi.org/10.1101/2020.11.04.368423
https://doi.org/10.1101/2020.11.04.368423
Publikováno v:
Cortex
Even within healthy aging, vascular risk factors can detrimentally influence cognition, with executive functions (EF) particularly vulnerable. Fronto-parietal white matter (WM) connectivity in part, supports EF and may be particularly sensitive to va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec5e22c16a3311aa3965e38c90b12b0c
https://doi.org/10.1101/2020.05.14.096677
https://doi.org/10.1101/2020.05.14.096677
Autor:
David J. Madden, Maria A. Boylan, David A. Hoagey, Catherine W. Tallman, Micah A. Johnson, Sally B. Cocjin, Jesse A. Honig, Lauren E. Packard, Rachel E. Siciliano, Ying Hui Chou, Guy G. Potter, Zachary A. Monge, Michele T. Diaz, Nan-kuei Chen, Emily L. Parks
Publikováno v:
Neurobiology of Aging. 54:199-213
Age-related decline in fluid cognition can be characterized as a disconnection among specific brain structures, leading to a decline in functional efficiency. The potential sources of disconnection, however, are unclear. We investigated imaging measu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbe3e189817b68edb7b69664b79f1cf0
https://doi.org/10.1016/j.neurobiolaging.2017.01.027
https://doi.org/10.1016/j.neurobiolaging.2017.01.027
Autor:
Nan-kuei Chen, Guy G. Potter, Sally B. Cocjin, Emily L. Parks, David J. Madden, Michele T. Diaz, Maria A. Boylan, Ying Hui Chou, Catherine W. Tallman, Rachel E. Siciliano, Zachary A. Monge, Micah A. Johnson, David A. Hoagey, Lauren E. Packard
Publikováno v:
Human Brain Mapping. 38:2128-2149
We conducted functional magnetic resonance imaging (fMRI) with a visual search paradigm to test the hypothesis that aging is associated with increased frontoparietal involvement in both target detection and bottom-up attentional guidance (featural sa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1b51f826f0cd0e0ccce47566ecabc6c
https://doi.org/10.1002/hbm.23509
https://doi.org/10.1002/hbm.23509
Publikováno v:
Neurobiol Aging
Despite the importance of cortico-striatal circuits to cognition, investigation of age effects on the structural circuitry connecting these regions is limited. The current study examined age effects on frontostriatal white matter connectivity, and id
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::123e5d4fbc4e7ea26cabc02ba1378f8f
https://pubmed.ncbi.nlm.nih.gov/32623262
https://pubmed.ncbi.nlm.nih.gov/32623262
Publikováno v:
NeuroImage. 185
Non-heme iron homeostasis interacts with inflammation bidirectionally, and both contribute to age-related decline in brain structure and function via oxidative stress. Thus, individuals with genetic predisposition for inflammation may be at greater r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20103637b627024405070b2183b41e8e
https://pubmed.ncbi.nlm.nih.gov/30395929
https://pubmed.ncbi.nlm.nih.gov/30395929
Beta-amyloid (Aβ) positive individuals hyper-activate brain regions compared to those not at-risk; however, hyperactivation is then thought to diminish as Alzheimer's disease symptomatology begins, evidencing eventual hypoactivation. It remains uncl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::111886c7f4de837270025aa83c54f944
https://europepmc.org/articles/PMC5747976/
https://europepmc.org/articles/PMC5747976/
Publikováno v:
Journal of Alzheimer's disease : JAD. 60(2)
Financial capacity (FC) is a cognitively complex activity of daily living that declines in mild cognitive impairment (MCI) and Alzheimer's disease (AD), limiting an individual's ability to manage one's finances and function independently. The neural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54628a551ce4e5ace3d258d056c021b3
https://pubmed.ncbi.nlm.nih.gov/28826185
https://pubmed.ncbi.nlm.nih.gov/28826185
Publikováno v:
Alzheimer's & Dementia. 13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::589d37fe696671b11c5508e6cdbb0a5e
https://doi.org/10.1016/j.jalz.2017.06.2391
https://doi.org/10.1016/j.jalz.2017.06.2391