Zobrazeno 1 - 10
of 1 325
pro vyhledávání: '"David A. Hart,"'
Publikováno v:
European Medical Journal, Vol 4, Iss 1, Pp 63-70 (2019)
Obesity is known to affect a high percentage of both adults and children in developed countries. Individuals with obesity are at risk of developing a number of comorbidities, as well as metabolic syndrome, which can create a low-grade systemic inflam
Externí odkaz:
https://doaj.org/article/f2a3078d331d495ca3278a9206a95197
Autor:
Prism S. Schneider, MD, PhD, FRCSC, Herman Johal, MD, MSc, FRCSC, A. Dean Befus, PhD, Paul T. Salo, MD, FRCSC, David A. Hart, PhD, Kevin A. Hildebrand, MD, FRCSC
Publikováno v:
JBJS Open Access, Vol 6, Iss 1 (2021)
Background:. Posttraumatic joint contracture is a debilitating complication following an acute fracture or intra-articular injury that can lead to loss of motion and an inability to complete activities of daily living. In prior studies using an estab
Externí odkaz:
https://doaj.org/article/b882bd4c03084b89beda63bb7ba9452c
Autor:
Nada Abughazaleh, Hannah Smith, Ruth-Anne Seerattan, David A. Hart, Raylene A. Reimer, Walter Herzog
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Oligofructose prebiotic fiber supplementation has been reported to mitigate the effects of a high fat/high sucrose diet and reduce knee joint degeneration in male rats. However, few studies investigated the development of osteoarthritis and
Externí odkaz:
https://doaj.org/article/8df1bccc9c1a40f38d92631dbc461afc
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 6, Iss 4, Pp 100521- (2024)
Objective: To develop a novel scoring system to characterize osteoarthritis-related degeneration distinct from spontaneous subchondral bone lesions observed in the tibia and femur of male Sprague Dawley rats. Method: Knee joints from male rats follow
Externí odkaz:
https://doaj.org/article/17f74ff2d3ee44b9b55f37e4d30d13e6
Autor:
Ania Kania-Richmond, Lauren A. Beaupre, Geneviève Jessiman-Perreault, Danika Tribo, Jason Martyn, David A. Hart, Jill Robert, Mel Slomp, C. Allyson Jones
Publikováno v:
Journal of Patient-Reported Outcomes, Vol 8, Iss 1, Pp 1-14 (2024)
Abstract Background The Good Life with osteoArthritis: Denmark (GLA:D™), an evidence-based education and exercise program designed for conservative management of knee and hip osteoarthritis (OA), has been shown to benefit participants by reducing p
Externí odkaz:
https://doaj.org/article/591e7462feff43668af0fd1f754a8bc2
Publikováno v:
Regenerative Therapy, Vol 26, Iss , Pp 124-131 (2024)
Treatments for articular cartilage injuries are still challenging, due in part to its avascular and aneural surroundings. Since the first report of autologous chondrocyte implantation, cell-based therapies have been extensively studied with a variety
Externí odkaz:
https://doaj.org/article/d4caba76b41c48ea94fdd00b1c9d56b7
Autor:
Manmeet S. Dhiman, Taylor J. Bader, Dragana Ponjevic, Paul T. Salo, David A. Hart, Ganesh Swamy, John R. Matyas, Neil A. Duncan
Publikováno v:
JOR Spine, Vol 7, Iss 3, Pp n/a-n/a (2024)
Abstract Introduction Degenerative disc disease (DDD) is accompanied by structural changes in the intervertebral discs (IVD). Extra‐cellular matrix degradation of the annulus fibrosus (AF) has been linked with degeneration of the IVD. Collagen is a
Externí odkaz:
https://doaj.org/article/436a730e48364e9ca1ce1b9893c9a13f
Autor:
David A. Hart
Publikováno v:
Biophysica, Vol 4, Iss 1, Pp 1-21 (2024)
Life on Earth evolved to accommodate the biochemical and biophysical boundary conditions of the planet millions of years ago. The former includes nutrients, water, and the ability to synthesize other needed chemicals. The latter includes the 1 g grav
Externí odkaz:
https://doaj.org/article/e9b2863aed594f938dfc5b58088d325e
Autor:
Shinichi Nakagawa, Wataru Ando, Kazunori Shimomura, David A. Hart, Hiroto Hanai, George Jacob, Ryota Chijimatsu, Seido Yarimitu, Hiromichi Fujie, Seiji Okada, Noriyuki Tsumaki, Norimasa Nakamura
Publikováno v:
npj Regenerative Medicine, Vol 8, Iss 1, Pp 1-14 (2023)
Abstract Both mesenchymal stromal cells (MSC) and induced pluripotent stem cells (iPSC) offer the potential for repair of damaged connective tissues. The use of hybrid implants containing both human MSC and iPSC was investigated to assess their combi
Externí odkaz:
https://doaj.org/article/b066bc449240489ea14dcdf8fa4f1c68
Autor:
David A. Hart
Publikováno v:
Biomolecules, Vol 14, Iss 8, p 905 (2024)
Lithium is one of the lightest elements on Earth and it has been in the environment since the formation of the galaxy. While a common element, it has not been found to be an essential element in biological processes, ranging from single cell organism
Externí odkaz:
https://doaj.org/article/cb6fffccba014f1cad730bcf3cc872c9