Zobrazeno 1 - 10
of 77
pro vyhledávání: '"David A. Gillett"'
Publikováno v:
Ecological Indicators, Vol 160, Iss , Pp 111791- (2024)
Statistical stressor-response models are a common approach to derive biologically relevant water quality criteria for the management of waterbody health. These types of models are typically derived at state-wide or ecoregional scales and consequently
Externí odkaz:
https://doaj.org/article/7966a727b71c435292796167a5f2f517
Publikováno v:
Australasian Journal of Plastic Surgery, Vol 6, Iss 1 (2023)
**Background**: Cleft lip repair is technically challenging surgery that requires an appreciation of the complex anatomy of the lip and nose. Effective transference of skill has been demonstrated through the use of simulations. We established a cleft
Externí odkaz:
https://doaj.org/article/cdc37beeccec481c8d02c0a89381157f
Publikováno v:
Ecological Indicators, Vol 143, Iss , Pp 109404- (2022)
Estuaries, lagoons, and embayments are key components of the coastal ecosystem and they are pervasively exposed to a variety of stressors – the most common of which is eutrophication. In shallow water coastal systems, eutrophication typically manif
Externí odkaz:
https://doaj.org/article/5e273d8ff26c43e8be35876c75f5db29
Publikováno v:
Frontiers in Marine Science, Vol 8 (2021)
Infauna are an ecologically important component of marine benthic ecosystems and are the most common faunal assemblage used to assess habitat quality. Compared to the shallower waters of the continental shelf, less is known about the benthic fauna fr
Externí odkaz:
https://doaj.org/article/1c4a14b2a3b74f229a6229b27e88ad76
Autor:
Marcus W. Beck, Casey O’Hara, Julia S. Stewart Lowndes, Raphael D. Mazor, Susanna Theroux, David J. Gillett, Belize Lane, Gregory Gearheart
Publikováno v:
PeerJ, Vol 8, p e9539 (2020)
Open science principles that seek to improve science can effectively bridge the gap between researchers and environmental managers. However, widespread adoption has yet to gain traction for the development and application of bioassessment products. A
Externí odkaz:
https://doaj.org/article/f65fb189d4374634a511b4ca62b90f68
Cellular and Structural Basis of Synthesis of the Unique Intermediate Dehydro-F420-0 in Mycobacteria
Autor:
Rhys Grinter, Blair Ney, Rajini Brammananth, Christopher K. Barlow, Paul R. F. Cordero, David L. Gillett, Thierry Izoré, Max J. Cryle, Liam K. Harold, Gregory M. Cook, George Taiaroa, Deborah A. Williamson, Andrew C. Warden, John G. Oakeshott, Matthew C. Taylor, Paul K. Crellin, Colin J. Jackson, Ralf B. Schittenhelm, Ross L. Coppel, Chris Greening
Publikováno v:
mSystems, Vol 5, Iss 3 (2020)
ABSTRACT F420 is a low-potential redox cofactor used by diverse bacteria and archaea. In mycobacteria, this cofactor has multiple roles, including adaptation to redox stress, cell wall biosynthesis, and activation of the clinical antitubercular prodr
Externí odkaz:
https://doaj.org/article/b31841d86def486ba529324116760dbf
Autor:
Jessica L. Bridgford, Stanley C. Xie, Simon A. Cobbold, Charisse Flerida A. Pasaje, Susann Herrmann, Tuo Yang, David L. Gillett, Lawrence R. Dick, Stuart A. Ralph, Con Dogovski, Natalie J. Spillman, Leann Tilley
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Artemisinin (ART) is a widely used antimalarial drug, but its mechanism of action is poorly understood. Here, Bridgford et al. show that ART kills parasites by a two-pronged mechanism, causing protein damage and compromising proteasome function, and
Externí odkaz:
https://doaj.org/article/65e9ecff6a5e4bf9bde0b3289d249518
Autor:
Stanley C. Xie, Riley D. Metcalfe, Elyse Dunn, Craig J. Morton, Shih-Chung Huang, Tanya Puhalovich, Yawei Du, Sergio Wittlin, Shuai Nie, Madeline R. Luth, Liting Ma, Mi-Sook Kim, Charisse Flerida A. Pasaje, Krittikorn Kumpornsin, Carlo Giannangelo, Fiona J. Houghton, Alisje Churchyard, Mufuliat T. Famodimu, Daniel C. Barry, David L. Gillett, Sumanta Dey, Clara C. Kosasih, William Newman, Jacquin C. Niles, Marcus C. S. Lee, Jake Baum, Sabine Ottilie, Elizabeth A. Winzeler, Darren J. Creek, Nicholas Williamson, Michael W. Parker, Stephen Brand, Steven P. Langston, Lawrence R. Dick, Michael D.W. Griffin, Alexandra E. Gould, Leann Tilley
Publikováno v:
Science. 376:1074-1079
Aminoacyl transfer RNA (tRNA) synthetases (aaRSs) are attractive drug targets, and we present class I and II aaRSs as previously unrecognized targets for adenosine 5′-monophosphate–mimicking nucleoside sulfamates. The target enzyme catalyzes the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33885bcc50dbddf18b27ef08501fecec
https://doi.org/10.1126/science.abn0611
https://doi.org/10.1126/science.abn0611
Autor:
Tuo Yang, Lee M. Yeoh, Madel V. Tutor, Matthew W. Dixon, Paul J. McMillan, Stanley C. Xie, Jessica L. Bridgford, David L. Gillett, Michael F. Duffy, Stuart A. Ralph, Malcolm J. McConville, Leann Tilley, Simon A. Cobbold
Publikováno v:
Cell Reports, Vol 29, Iss 9, Pp 2917-2928.e5 (2019)
Summary: Increased tolerance of Plasmodium falciparum to front-line artemisinin antimalarials (ARTs) is associated with mutations in Kelch13 (K13), although the precise role of K13 remains unclear. Here, we show that K13 mutations result in decreased
Externí odkaz:
https://doaj.org/article/8f39fae61eff431d8f068b8099d6e17e
Autor:
Ariel Levi Simons, Noah Aulerich, Harold Carlson, Inessa Chandra, Jordan Chancellor, Georgina Gemayel, David James Gillett, Dylan Levene, Jonathon Lin, Georgia Nichol, Hetal Patel, Serena Zhu
Publikováno v:
Journal of Coastal Research. 39
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d3cf817bf5f76bf8fb2d6502f5c50b4
https://doi.org/10.2112/jcoastres-d-22-00051.1
https://doi.org/10.2112/jcoastres-d-22-00051.1